ELISA-based assay for the detection of α- and γ-amanitins in urines;Syndrome phalloïdien: Quelle est la place du dosage des α- et γ-amanitines par ELISA (Bühlmann)? Résultats préliminaires

Acta Clinica Belgica

Volumn 61, Issue SUPPL. 1, 2006, Pages 11-17

  Parant, François ^a   Peltier, L ^a,b   Lardet, G ^a   Pulce, C ^b   Descotes, J ^b   Moulsma, M ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b Centre Antipoison   (France)

Author keywords

Amanitin; Amatoxin poisoning; ELISA

Indexed keywords

ALPHA AMANITIN; AMANITIN; PHALLOIDIN;

AMANITA PHALLOIDES; ANAMNESIS; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DEATH; DIAGNOSTIC KIT; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACTION; FECES LEVEL; FEMALE; FOOD CONTAMINATION; GASTROENTERITIS; HEPATIC COMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INGESTION; LIVER FAILURE; MALE; MUSHROOM; MUSHROOM POISONING; RADIOIMMUNOASSAY; SAFETY; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE; SYMPTOMATOLOGY; URINE LEVEL; CASE REPORT; SYNDROME; URINE;

AMANITINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MUSHROOM POISONING; PHALLOIDINE; SYNDROME;

EID: 33645759253     PISSN: 00015512     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. De Haro L, Prost N, Perringue C, Arditti J, David JM, Drouet G, Thomas M, Valli M. Intoxication par champignons: expérience du Centre Anti-Poison de Marseille en 1994 et 1998. Bull Épidémiol Hebd. 1999; 30: 1-8.
2. Barriot P, Masson B, Fournier S. Intoxications par les champignons. Rev Prat. 2000; 50: 396-400.
3. Berger KJ, Guss DA. Mycotoxins revisited: Part I. J Emerg Med. 2005; 28: 53-62.
4. Enjalbert F, Rapior S, Nouguier-Soule J, Guillon S, Amouroux N, Cabot C. Treatment of amatoxin poisoning: 20-year retrospective analysis. J Toxicol Clin Toxicol. 2002; 40: 715-57.
5. Ganzert M, Felgenhauer N, Zilker T. Indication of liver transplantation following amatoxin intoxication. J Hepatol. 2005; 42: 202-9.
6. Karlson-Stiber C, Persson H. Cytotoxic fungi - an overview. Toxicon. 2003; 42: 339-49.
7. Jaeger A, Jehl F, Flesch F, Sauder P, Kopferschmitt J. Kinetics of amatoxins in human poisoning: therapeutic implication. J Toxicol Clin Toxicol. 1993; 31: 63-80.
8. Homann J, Rawer P, Bleyl H, Matthes KJ, Heinrich D. Early detection of amatoxins in human mushroom poisoning. Arch Toxicol. 1986; 59: 190-1.
9. Butera R, Locatelli C, Coccini T, Manzo L. Diagnostic accuracy of urinary amanitin in suspected mushroom poisoning: a pilot study. J Toxicol Clin Toxicol. 2004; 42: 901-12.
10. Vetter J. Toxins of Amanita phalloides. Toxicon. 1998; 36: 13-24.
11. Wieland Th. Peptides of Poisonous Amanita Mushrooms (1st ed). Rich A. ed, Heidelberg, Springer Verlag: 1986: 256 pp.
12. Stijve T, Seeger T. Determination of alpha-, beta-, and gamma-amanitin by high performance thin-layer chromatography in Amanita phalloides (Vaill. ex Fr.). Z Naturforsch [C]. 1979; 34: 1133-8.
13. Vesconi S, Langer M, Iapichino C, Costantino D, Busi C, Fiume L. Therapy of cytotoxic mushroom intoxication. Crit Care Med. 1985; 13: 402-6.
14. Homann J, Rawer P, Bleyl H, Matthes KJ, Heinrich D. Early detection of amatoxins in human mushroom poisoning. Arch Toxicol. 1986; 59: 190-1.
15. Laboratoire Bühlmann. Amanitin-ELISA. Manuel d'instruction. Bühlmann Laboratories AG, Schönenbuch (Suisse), 2003.
16. Maurer HH, Schmitt CJ, Weber AA, Kraemer T. Validated electrospray liquid chromatographic-mass spectrometric assay for the determination of the mushroom toxins alpha- and beta-amanitin in urine after immunoaffinity extraction. J Chromatogr B Biomed Sci Appl. 2000; 748: 125-35.
17. Dorizzi R, Michelot D, Tagliaro F, Ghielmi S. Methods for chromatographic determination of amanitins and related toxins in biological samples. J Chromatogr. 1992; 580: 279-91.
18. Defendenti C, Bonacina E, Mauroni M, Gelosa L. Validation of a high performance liquid chromatographic method for alpha amanitin determination in urine. Forensic Sci Int. 1998; 92: 59-68.
19. 125I-tracer-based system. Clin Chem. 1986; 32: 1751-5.
20. Koppel C. Clinical symptomatology and management of mushroom poisoning. Toxicon. 1993; 31: 1513-40.
21. Staack R, Maurer HH. 2001. New Bühlmann ELISA for determination of Amanitins in urine - are there false positive results due to interferences with urine matrix, drugs or their metabolites? Toxichem Krimteck. 2001; 68: 68-71.
22. Bonnet MS, Basson PW. The toxicology of Amanita phalloides. Homeopathy. 2002; 9: 249-54.