Inhibitory effect of α-tocopherol on benzo(a)pyrene-induced CYPA1 activity in rat liver

Bulletin of Experimental Biology and Medicine

Volumn 140, Issue 5, 2005, Pages 517-520

  Sidorova, Yu A ^a   Grishanova, A Yu ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOPHYSICS   (Russian Federation)

Author keywords

tocopherol; Benzo(a)pyrene; CYP1A; Glutathione S transferase; NADPH cytochrome P450 reductase

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BENZO[A]PYRENE; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; ETHOXYRESORUFIN; FREE RADICAL; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER CYTOSOL; LIVER MICROSOME; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN PROCESSING; RAT; XENOBIOTIC METABOLISM;

ALPHA-TOCOPHEROL; ANIMALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE TRANSFERASE; LIVER; MALE; MICROSOMES, LIVER; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR; XENOBIOTICS;

ANIMALIA;

EID: 33645747555     PISSN: 00074888     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10517-006-0012-8     Document Type: Article

References (15)

1. L. I. Andreeva, Lab. Delo, 11, 41-43 (1988).
2. Yu. A. Sidorova, E. V. Ivanova, A. Yu. Grishanova, and V. V. Lyakhovich, Byull. Eksp. Biol. Med., 136, No. 7, 45-48 (2003).
3. T. V. Beischlag, S. Wang, D. W. Rose, et al., Mol. Cell. Biol., 22, No. 12, 4319-4333 (2002).
4. R. Birgelius-Flohe and M. G. Traber, FASEB J., 13, 1145-1155 (1999).
5. M. D. Burke, S. Thompson, R. T. Mayer, et al., Biochem. Pharmacol., 34, 3337-3346 (1985).
6. M. S. Denison and S. R. D. Nagy, Ann. Rev. Pharmacol. Toxicol., 43, 309-334 (2003).
7. L. Ernster and K. Nordenbrandt, Meth. Enzymol., 10, 574-580 (1967).
8. W. H. Habig, M. J. Pabst, and W. B. Jakoby, J. Biol. Chem., 249, No. 22, 7130-7139 (1974).
9. E. V. Hestermann and M. Brown, Mol. Cell. Biol., 23, No. 21, 7920-7925 (2003).
10. O. U. Lowry, N. I. Rosebrough, A. L. Farr, and R. I. Randall, J. Biol. Chem., 153, 265-275 (1951).
11. Q. Ma, Curr. Drug Met., 2, 149-164 (2001).
12. M. Murray, Biochem. Pharmacol., 42, No. 11, 2107-2114 (1991).
13. A. H. Phillips and R. G. Langdon, J. Biol. Chem., 237, 2652-2660 (1962).
14. D. K. Ro, J. Ehlting, and C. J. Douglas, Plant Physiol., 130, No. 4, 1837-1851 (2002).
15. L. Yu. Zacharova, L. F. Gulyaeva, V. V. Lyakhovich, et al., Toxicol. Sci., 73, 108-113 (2003).