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Volumn 21, Issue 1, 2006, Pages 21-28

Attenuated expression of interferon-induced protein kinase PKR in a simian cell devoid of type I interferons

Author keywords

Alternative splicing; Exon 12 deletion; Interferon ; Simian PKR; Vero E6 cell

Indexed keywords

COMPLEMENTARY DNA; INTERFERON; PROTEIN KINASE R; ALPHA2A INTERFERON; MESSENGER RNA; PHOSPHOTRANSFERASE;

EID: 33645734642     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (24)
  • 1
    • 0032212772 scopus 로고    scopus 로고
    • The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia
    • Abraham, N., Jaramillo, M. L., Duncan, P. I., Methot, N., Icely, P. L., et al. (1998) The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia. Exp. Cell Res. 244, 394-404.
    • (1998) Exp. Cell Res. , vol.244 , pp. 394-404
    • Abraham, N.1    Jaramillo, M.L.2    Duncan, P.I.3    Methot, N.4    Icely, P.L.5
  • 2
    • 0037064118 scopus 로고    scopus 로고
    • Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR
    • Baltzis, D., Li, S., and Koromilas, A. E. (2002) Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR. J. Biol. Chem. 277, 38364-38372.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38364-38372
    • Baltzis, D.1    Li, S.2    Koromilas, A.E.3
  • 3
    • 0029061555 scopus 로고
    • Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation
    • Barber, G. N., Wambach, M., Thompson, S., Jagus, R., and Katze, M. G. (1995) Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation. Mol. Cell. Biol. 15, 3138-3146.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3138-3146
    • Barber, G.N.1    Wambach, M.2    Thompson, S.3    Jagus, R.4    Katze, M.G.5
  • 4
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • Clemens, M. J. and Androulla, E. (1997) The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Cytokine Res. 17, 503-524.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 503-524
    • Clemens, M.J.1    Androulla, E.2
  • 5
    • 0001122795 scopus 로고
    • Homologous deletion of the alpha- and beta 1 interferon genes in human leukemia and derived cell lines
    • Diaz, M. O., Ziemin, S., Le Beau, M. M., Pitha, P., Smith, S. D., et al. (1988) Homologous deletion of the alpha- and beta 1 interferon genes in human leukemia and derived cell lines. Proc. Natl. Acad. Sci. USA 85, 5259-5263.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5259-5263
    • Diaz, M.O.1    Ziemin, S.2    Le Beau, M.M.3    Pitha, P.4    Smith, S.D.5
  • 6
    • 0026653870 scopus 로고
    • Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase
    • Feng, G. S., Chong, K., Kumar, A., and Williams, B. R. G. (1992) Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase. Proc. Natl. Acad. Sci. USA 89, 5447-5451.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5447-5451
    • Feng, G.S.1    Chong, K.2    Kumar, A.3    Williams, B.R.G.4
  • 7
    • 0024212067 scopus 로고
    • Rapid production of full-length cDNA from rare transcripts: Amplification using a single gene specific oligonucleotide primer
    • Frohman, M. A., Dush, M. K., and Martin, G. R. (1988) Rapid production of full-length cDNA from rare transcripts: Amplification using a single gene specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85, 8998-9002.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8998-9002
    • Frohman, M.A.1    Dush, M.K.2    Martin, G.R.3
  • 8
    • 0345164384 scopus 로고    scopus 로고
    • Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase
    • Gale, M. Jr. and Katze, M. J. (1998) Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase. Pharmacol. Ther. 78, 29-46.
    • (1998) Pharmacol. Ther. , vol.78 , pp. 29-46
    • Gale Jr., M.1    Katze, M.J.2
  • 9
    • 0024797894 scopus 로고
    • Protein phosphorylation controls translation rates
    • Hershey, J. W. B. (1989) Protein phosphorylation controls translation rates. J. Biol. Chem. 264, 20823-20826.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20823-20826
    • Hershey, J.W.B.1
  • 10
    • 0025999848 scopus 로고
    • TIK, a novel serine/threonine kinase, is recognized by antibodies directed against phosphotyrosine
    • Icely, P. L., Gross, P., Bergeron, J. J. M., Devault, A., Afar, D. E. H., et al. (1991) TIK, a novel serine/threonine kinase, is recognized by antibodies directed against phosphotyrosine. J. Biol. Chem. 266, 16073-16077.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16073-16077
    • Icely, P.L.1    Gross, P.2    Bergeron, J.J.M.3    Devault, A.4    Afar, D.E.H.5
  • 11
    • 0026042013 scopus 로고
    • Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell free system
    • Katze, M. G., Wambach, M., Wong, M.-L., Garfinkel, M., Meurs, E., et al. (1991) Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell free system. Mol. Cell. Biol. 11, 5497-5505.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5497-5505
    • Katze, M.G.1    Wambach, M.2    Wong, M.-L.3    Garfinkel, M.4    Meurs, E.5
  • 12
    • 0026701570 scopus 로고
    • Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase
    • Koromilas, A. E., Roy, S., Barber, G. N., Katze, M. G., and Sonenberg, N. (1992) Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science 257, 1685-1689.
    • (1992) Science , vol.257 , pp. 1685-1689
    • Koromilas, A.E.1    Roy, S.2    Barber, G.N.3    Katze, M.G.4    Sonenberg, N.5
  • 13
    • 0028332026 scopus 로고
    • Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B
    • Kumar, A., Haque, J., Lacoste, J., Hiscott, J., and Williams, B. R. (1994) Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc. Natl. Acad. Sci. USA 91, 6288-6292.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6288-6292
    • Kumar, A.1    Haque, J.2    Lacoste, J.3    Hiscott, J.4    Williams, B.R.5
  • 14
    • 0027157746 scopus 로고
    • The interferon-induced double-stranded RNA-activated human p68 protein kinanse inhibits the replication of vaccinia virus
    • Lee, S. B. and Esteban, M. (1993) The interferon-induced double-stranded RNA-activated human p68 protein kinanse inhibits the replication of vaccinia virus. Virology 193, 1037-1041.
    • (1993) Virology , vol.193 , pp. 1037-1041
    • Lee, S.B.1    Esteban, M.2
  • 15
    • 0035957939 scopus 로고    scopus 로고
    • Dominant negative function by an alternative spliced form of the interferon-inducible protein kinase PKR
    • Li, S. and Koromilas, A. E. (2001) Dominant negative function by an alternative spliced form of the interferon-inducible protein kinase PKR. J. Biol. Chem. 276, 13881-13890.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13881-13890
    • Li, S.1    Koromilas, A.E.2
  • 16
    • 0027938042 scopus 로고
    • Cloning and characterization of a cDNA encoding rat PKR, the double-stranded RNA-dependent eukaryotic initiation factor-2 kinase
    • Mellor, H., Flowers, K. M., Kimball, S. R., and Jefferson, L. S. (1994) Cloning and characterization of a cDNA encoding rat PKR, the double-stranded RNA-dependent eukaryotic initiation factor-2 kinase. Biochim. Biophys. Acta 1219, 693-696.
    • (1994) Biochim. Biophys. Acta , vol.1219 , pp. 693-696
    • Mellor, H.1    Flowers, K.M.2    Kimball, S.R.3    Jefferson, L.S.4
  • 17
    • 0025298202 scopus 로고
    • Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
    • Meurs, E., Chang, K., Galabru, J., Thomas, N. S., Kerr, I. M., et al. (1990) Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62, 379-390.
    • (1990) Cell , vol.62 , pp. 379-390
    • Meurs, E.1    Chang, K.2    Galabru, J.3    Thomas, N.S.4    Kerr, I.M.5
  • 18
    • 0026929934 scopus 로고
    • Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth
    • Meurs, E. F., Wantanabe, Y., Kadereit, S., Barber, G. N., Katze, M. G., et al. (1992) Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66, 5805-5814.
    • (1992) J. Virol. , vol.66 , pp. 5805-5814
    • Meurs, E.F.1    Wantanabe, Y.2    Kadereit, S.3    Barber, G.N.4    Katze, M.G.5
  • 19
    • 0027396813 scopus 로고
    • Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase
    • Meurs, E. F., Galabru, J., Barber, G. N., Katze, M. G., and Hovanessian, A. G. (1993) Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. USA 90, 232-236.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 232-236
    • Meurs, E.F.1    Galabru, J.2    Barber, G.N.3    Katze, M.G.4    Hovanessian, A.G.5
  • 20
    • 0040350202 scopus 로고
    • Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase
    • Samuel, C. E. (1979) Mechanism of interferon action: phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA 76, 600-604.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 600-604
    • Samuel, C.E.1
  • 21
    • 0027418321 scopus 로고
    • The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans
    • Samuel, C. E. (1993) The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 268, 7603-7606.
    • (1993) J. Biol. Chem. , vol.268 , pp. 7603-7606
    • Samuel, C.E.1
  • 22
    • 0032811002 scopus 로고    scopus 로고
    • The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: A new face of death?
    • Tan, S. L. and Katze, M. G. (1999) The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death? J. Interferon Cytokine Res. 19, 543-554.
    • (1999) J. Interferon Cytokine Res. , vol.19 , pp. 543-554
    • Tan, S.L.1    Katze, M.G.2
  • 23
    • 0026716253 scopus 로고
    • Mechanism of interferon action: CDNA structure, expression and regulation of the interferon-induced, RNA-dependent PI/eIF-2α protein kinase from human cells
    • Thomis, D. C., Doohan, J. D., and Samuel, C. E. (1992) Mechanism of interferon action: cDNA structure, expression and regulation of the interferon-induced, RNA-dependent PI/eIF-2α protein kinase from human cells. Virology 188, 33-46.
    • (1992) Virology , vol.188 , pp. 33-46
    • Thomis, D.C.1    Doohan, J.D.2    Samuel, C.E.3
  • 24
    • 0031849783 scopus 로고    scopus 로고
    • Genomic features of human PKR: Alternative splicing and a polymorphic CGG repeat in the 5′-untranslated region
    • Xu, Z. and Williams, B. R. (1998) Genomic features of human PKR: alternative splicing and a polymorphic CGG repeat in the 5′-untranslated region. J. Interferon Cytokine Res. 18, 609-616.
    • (1998) J. Interferon Cytokine Res. , vol.18 , pp. 609-616
    • Xu, Z.1    Williams, B.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.