Analysis of kanamycin A in human plasma and in oral dosage form by derivatization with 1-naphthnyl isothiocyanate and high-performance liquid chromatography

Journal of Separation Science

Volumn 29, Issue 5, 2006, Pages 607-612

  Chen, Su Hwei ^a,b   Liang, Yi Chian ^b   Chou, Yu Wei ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Commercial kanamycin formulations; HPLC; Kanamycin A; Naphthyl isothiocyanate derivatization; Plasma

Indexed keywords

ACETONITRILE; ANTIBIOTICS; CHEMICAL REACTIONS; DRUG DOSAGE; MIXTURES; PLASMAS; PRECIPITATION (CHEMICAL); PROTEINS;

CHEMICAL DERIVATIZATION; COMMERCIAL KANAMYCIN FORMULATIONS; KANAMYCIN A; NAPHTHYL ISOTHIOCYANATE DERIVATIZATION; REACTION MIXTURE;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1 NAPHTHYL ISOTHIOCYANATE; ACETONITRILE; KANAMYCIN A; METHANOL; METHYLAMINE; PYRIDINE; WATER;

ACCURACY; ARTICLE; BLOOD SAMPLING; CHEMICAL REACTION; CONTROLLED STUDY; DERIVATIZATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE REGIMEN; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; SIGNAL NOISE RATIO;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; ISOTHIOCYANATES; KANAMYCIN; MOLECULAR STRUCTURE; NAPHTHALENES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33645733470     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200500450     Document Type: Article

References (18)

1. Hardman, J. G., Limbird, L. E., Gilman, A. G. (Eds.), Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th Edn., McGraw-Hill, New York 2001, p. 1234.
2. Claes, P. J., Dubost, M., Vanderhaeghe, H., Florey, K. (Eds.), Analytical Profiles of Drug Substances, Vol. 6, Academic Press, New York 1979, p. 259.
3. Katzung, B. G. (Ed.), Basic & Clinical Pharmacology, 9th Edn., McGraw-Hill, New York 2004, pp. 767-770.
4. Olin, B. R. (Ed.), Drug Facts and Comparisons, 50th Edn., Facts and Comparisons, St. Louis 1996, p. 2157.
5. Watanabe, H., Satake, A., Kido, Y., Tsuji, A., Analyst 1999, 124, 1611-1615.
6. Loomans, E. E. M. G., Wiltenburge, J. V., Koets, M., Amerongen, A. V., J. Agric. Food Chem. 2003, 51, 587-593.
7. Gupta, V. D., Stewart, K. R., Gunter, J. M., J. Pharm. Sci. 1983, 72, 1470-1471.
8. Ryan, J. A., J. Pharm. Sci. 1984, 73, 1301-1302.
9. Preu, M., Guyot, D., Petz, M., J. Chromatogr. A 1998, 818, 95-108.
10. Elrod, J. L., White, L. B., Spanton, S. G., Stroz, D. G., Cugier, P. J., Luka, A., Anal. Chem. 1984, 56, 1786-1790.
11. Kim, B. H., Kim, Y. K., Ok, J. H., J. Chromatogr. B 2001, 752, 173-177.
12. Caturla, M. C., Cusido, E., Westerlund, D., J. Chromatogr. 1992, 593, 69-72.
13. Morovjan, G., Csokan, P. P., Nemeth-Konda, L., Chromatographia 1998, 48, 32-36.
14. Gambardella, P., Punziano, R., Gionti, M., Guadalupi, C., Mancini, G., J. Chromatogr. 1985, 348, 229-240.
15. U.S. Pharmacopoeia 27, NF 22 Revision, United States Pharmacopeial Convention, Inc., Rockville, MD, 2004, pp. 1052-1053.
16. Kaale, E., Schepdael, A. V., Roets, E., Hoogmarten, J., J. Chromatogr. A 2001, 924, 451-458.
17. Kaale, E., Schepdael, A. V., Roets, E., Hoogmartens, J., Electrophoresis 2003, 24, 1119-1125.
18. Yeh, H. H., Lin, S. J., Ko, J. Y., Chou, C. A., Chen, S. H., Electrophoresis 2005, 26, 947-953.