Pulsatile flow and mass transport over an array of cylinders: Gas transfer in a cardiac-driven artificial lung

Journal of Biomechanical Engineering

Volumn 128, Issue 1, 2006, Pages 85-96

  Chain, Kit Yan ^a   Fujioka, Hideki ^a   Bartlett, Robert H ^b   Hirschl, Ronald B ^b   Grotberg, James B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Artificial lung; Cylinder array; Gas transfer; Pulsatile flow

Indexed keywords

ARTIFICIAL ORGANS; BIOLOGICAL ORGANS; MASS TRANSFER; NUMERICAL METHODS; PULSATILE FLOW; REYNOLDS NUMBER;

ARTIFICIAL LUNGS; CYLINDER ARRAY; VOID FRACTIONS;

BIOMEDICAL ENGINEERING;

ARTICLE; ARTIFICIAL LUNG; BLOOD FLOW; CYLINDER ARRAY; DEVICE; FIBER; FLOW KINETICS; FLOW RESISTANCE; GAS DIFFUSION; GEOMETRY; HEART RIGHT VENTRICLE; LIQUID; MASS TRANSPORT; MATHEMATICAL ANALYSIS; MICROFIBER; NEWTONIAN PASSIVE FLUID; OSCILLATION; PHYSICAL PHENOMENA; PRESSURE GRADIENT; PULSATILE FLOW; REYNOLDS NUMBER; STEADY FLOW; SYSTEMS BIOLOGY;

ARTIFICIAL ORGANS; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD FLOW VELOCITY; COMPUTER SIMULATION; EQUIPMENT FAILURE ANALYSIS; GASES; HEART; HUMANS; LUNG; MODELS, CARDIOVASCULAR; PULMONARY CIRCULATION; PULMONARY GAS EXCHANGE; PULSATILE FLOW; RESPIRATORY TRANSPORT;

EID: 33645711207     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2133761     Document Type: Article

References (28)

1. Fazzalari, F. L., Bartlett, R. H. et al., 1994, "An Intrapleural Lung Prothesis-Rationale, Design, and Testing," Artif. Organs, 18(11), pp. 801-805.
2. Lynch, W. R., Montoya, J. P. et al., 2000, "Hemodynamic Effect of a Low-Resistance Artificial Lung in Series With the Native Lungs of Sheep," Ann. Thorac. Surg., 69(2), pp. 351-356.
3. Zwischenberger, J. B., and Alpard, S. K., 2002, "Artificial Lungs: A New Inspiration," Perfusion, 17(4), pp. 253-268.
4. Ichinose, K., Okamoto, T. et al., 2004, "Comparison of a New Heparin-Coated Dense Membrane Lung With Nonheparin-Coated Dense Membrane Lung for Prolonged Extracorporeal Lung Assist in Goats," Artif. Organs, 28(11), pp. 993-1001.
5. Haft, J. W., Griffith, B. P. et al., 2002, "Results of an Artificial-Lung Survey to Lung Transplant Program Directors," J. Heart Lung Transplant, 21(4), pp. 467-472.
6. Vaslef, S. N., Mockros, L. F. et al., 1994, "Use of a Mathematical Model to Predict Oxygen Transfer Rates in Hollow Fiber Membrane Oxygenators," ASAIO J., 40, pp. 990-996.
7. Vaslef S. N., Mockros, L. F., et al., 1994, "Computer-Assisted Design of an Implantable, Intrathoracic Artificial Lung," Artif. Organs, 18(11), pp. 813-817.
8. Hewitt, T. J., Hauler, B. G. et al., 1998, "A Mathematical Model of Gas Exchange in an Intravenous Membrane Oxygenator," Ann. Biomed. Eng., 26(1), pp. 166-178.
9. Dieriekx, P. W., De Somer, F. et al., 2000, "Hydrodynamic Characteristics of Artificial Lungs," ASAIO J., 46(5), pp. 532-535.
10. Kanamori, T., Niwa, M. et al., 2000, "Estimate of Gas Transfer Rates of Intravascular Membrane Oxygenator"" ASAIO J., 46(5), pp612-619.
11. Dieriekx, P. W., De Wachter, D. S. et al., 2001, "Mass Transfer Characteristics of Artificial Lungs," ASAIO J., 47(6), pp. 628-633.
12. Weissman, M. H., and Mockros, L. F. 1968, "Oxygen and Carbon Dioxide Transfer in Membrane Oxygenators," Med. Biol. Eng., 7, pp. 169-184.
13. Smeby, L., and Grimsrud, L., 1974, "Theoretical Investigation of Mass Transfer in Membrane Oxygenators," Med. Biol. Eng., 12(5), pp. 698-706.
14. Dorson, W. J., Larsen, K. G. et al., 1971, "Oxygen Transfer to Blood: Data and Theory," Trails. Am. Soc. Artif. Intern. Organs, 17, pp. 309-316.
15. Baker, D. A., Holte, J. E. et al., 1991, "Computationally Two-Dimensional Finite-Difference Model for Hollow-Fiber Blood-Gas Exchange Device," Med. Biol. Eng. Comput., 29. pp. 482-488.
16. Wang, N. H. L., and Keller, N. H., 1979, "Solute Transport Induced by Erythrocyte Motions in Shear-Flow," Trans. Am. Soc. Artif. Intern. Organs, 25, pp. 14-18.
17. Wang, N. H. L., and Keller, N. H., 1985, "Augmented Transport of Extracellular Solutes in Concentrated Erythrocyte Suspensions in Couette-Flow," J. Colloid Interface Sci., 103(1), pp. 210-225.
18. Dierickx, P. W. T., De Wachter, D. et al., 2000, "Blood Flow Around Hollow Fibers," Int. J. Artif. Organs, 23(9), pp. 610-617.
19. Dierickx, P. W., De Wachter, D. S. et al., 2001, "Two-Dimensional Finite Element Model for Oxygen Transfer in Cross-Flow Hollow Fiber Membrane Artificial Lungs," Int. J. Artif. Organs, 24(9), pp. 628-635.
20. Mockros, L. F., and Gaylor, J. D. S., 1975, "Artificial Lung Design-Tubular Membrane Units," Med. Biol. Eng., 13(2), pp. 171-181.
21. Gage, K. L., Gartner, M. J. et al., 2002, "Predicting Membrane Oxygenator Pressure Drop Using Computational Fluid Dynamics," Artif. Organs, 26(7), pp. 600-607.
22. Boschetti, F. Cook, K. E. et al., 2003, "Blood Flow Pulsatility Effects Upon Oxygen Transfer in Artificial Lungs," ASAIO J., 49(6), pp. 678-686.
23. Pennati, G., Fiore, G. B. et al., 1998, "Mass Transfer Efficiency of a Commercial Hollow Fiber Oxygenator During Six-Hour in vitro Perfusion With Steady and Pulsatile Blood Flow," Int. J. Artif. Organs, 21(2), pp. 97-106.
24. Haft, J. W., Bull, J. L. et al., 2003, "Design of an Artificial Lung Compliance Chamber for Pulmonary Replacement," ASAIO J., 49(1), pp. 35-40.
25. Thompson, J. F., Soni, B. K. et al., 1999, Handbook of Grid Generation, CRC Press, Boca Raton.
26. Patankar, S. V., 1980, Numerical Heal Transfer and Fluid Flow, Hemisphere Pub. Corp., McGraw-Hill, New York, Washington.
27. Edwards, D. A., Shapiro, M. et al., 1990, "The Influence of Reynolds Number Upon the Apparent Permeability of Spatially Periodic Arrays of Cylinders," Phys. Fluids A, 2(1), pp. 45-55.
28. Ghaddar, C. K., 1995, "On the Permeability of Unidirectional Fibrous Media: A Parallel Computational Approach," Phys. Fluids, 7(11), pp. 2563-2585.