SPE/TLC profiling of the impurities of MDMA: The influence of an agglutinant, diluents, and adulterants

Journal of Liquid Chromatography and Related Technologies

Volumn 29, Issue 9, 2006, Pages 1247-1256

  Kochana, J ^a   Parczewski, A ^b   Wilamowski, J ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b INSTITUTE OF FORENSIC RESEARCH   (Poland)

Author keywords

MDMA; Profiling of impurities; SPE TLC

Indexed keywords

DISSOLUTION; DRUG PRODUCTS; EXTRACTION; IMPURITIES; SOLUTIONS;

MDMA; PROFILING OF IMPURITIES; SPE/TLC;

LIQUID CHROMATOGRAPHY;

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACETYLSALICYLIC ACID; BUFFER; CAFFEINE; CITRIC ACID; DRUG ADDITIVE; GLUCOSE; MAGNESIUM STEARATE; PARACETAMOL;

ARTICLE; DISSOLUTION; DRUG ANALYSIS; FLUORESCENCE; QUANTITATIVE ANALYSIS; SCREENING; TABLET; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

EID: 33645700093     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070600598894     Document Type: Article

References (15)

1. European monitoring centre for drugs and drugs addition, Recreational drug use - a key EU challenge. Drugs in Focus Nov-Dec, 2002.
2. Gimeno, P.; Besacier, F.; Chaudron-Thozet, H. Optimization of extraction parameters for chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets. Foren. Sci. Int. 2003, 132, 182-194.
3. Gimeno, P.; Besacier, F.; Chaudron-Thozet, H.; Girard, J.; Lamotte, A. A contribution to the chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets. Foren. Sci. Int. 2002, 127, 1-44.
4. Makino, Y.; Kurobane, S.; Miyasaka, K.; Nagano, K. Profiling of ecstasy tablets seized in Japan. Microgram J. 2003, 1 (3-4), 169-176.
5. Song, S.M.; Marriott, P.; Kotsos, A.; Drummer, O.H.; Wynne, P. Comprehensive two-dimentional gas chromatography with time-of-flight mass spectrometry (GC x GC-TOFMS) for drug screening and confirmation. Foren. Sci. Int. 2004, 143, 87-101.
6. Rashed, A.M.; Anderson, R.A.; King, L.A. Solid-phase extraction for profiling of Ecstasy tablets. J. Foren. Sci. 2000, 45 (2), 413-417.
7. Palhol, F.; Boyer, S.; Naulet, N.; Chabrillat, M. Impurity profiling of seized MDMA tablets by capillary gas chromatography. Anal. Bioanal. Chem. 2002, 374, 274-281.
8. Bell, S.E.J.; Barrett, L.J.; Burns, D.T.; Dennis, A.C.; Speers, S.J. Tracking the distribution of "ecstasy" tablets by Raman composition profiling: A large scale feasibility study. Analyst 2003, 128 (11), 1331-1335.
9. Cheng, W.C.; Poon, N.L.; Chan, M.F. Chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong. J. Foren. Sci. 2003, 48 (6).
10. 14N isotopic ratio and statistical analysis: an efficient way of linking Ecstasy tablets. Anal. Chim. Acta 2004, 510, 1-8.
11. Kochana, J.; Wilamowski, J.; Parczewski, A. TLC profiling of 1-(3,4-methylenedioxyphenyl)-2-nitropropene an intermediate in MDMA synthesis. Influence of sample preparation methods and conditions. J. Liq. Chromatogr. & Rel. Technol. 2004, 27 (15), 2463-2470.
12. Kochana, J.; Wilamowski, J.; Parczewski, A. SPE-TLC profiling of impurities in 1-(3,4-methylenedioxyphenyl)-2-nitropropene, an intermediate in 3,4-methylenedioxymethamphetamine (MDMA) synthesis. Chromatographia 2004, 60 (7/8), 481-484.
13. 4 factorial. Foren. Sci. Int. 2003, 134, 214-218.
14. Kellner, R.; Mermet, J.-M.; Otto, M.; Valcarcel, M.; Widmer, H.M. Analytical Chemistry. A modern approach to Analytical Science; Wiley-VCH Verlag GmbH & Co. KgaA: Germany, 2004, 151-158.
15. Kochana, J.; Wilamowski, J.; Parczewski, A.; Surma, M. Synthesis of standards of the most important markers of Leuckart p-methoxymethamphetamine (PMMA). Examination of the influence of experimental conditions and a drug diluent on SPE/TLC profiling. Foren. Sci. Int. 2003, 134, 207-213.