1,4-Benzodiazepines as inhibitors of respiratory syncytial virus

Journal of Medicinal Chemistry

Volumn 49, Issue 7, 2006, Pages 2311-2319

  Carter, Malcolm C ^a   Alber, Dagmar G ^a   Baxter, Robert C ^a   Bithell, Sian K ^a   Budworth, Jo ^a   Chubb, Ann ^a   Cockerill, G Stuart ^a   Dowdell, Verity C L ^a   Henderson, Elisa A ^a   Keegan, Sally J ^a   Kelsey, Richard D ^a   Lockyer, Michael J ^a   Stables, Jeremy N ^a   Wilson, Lara J ^a   Powell, Kenneth L ^a  

^a Arrow Therapeutics   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 FLUOROPHENYL) 3 (2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 3 YL)UREA; 2 METHOXY 4 NITRO N (2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 3 YL) BENZAMIDE; 2,3 BIS(2 METHOXY 4 NITRO 5 SULFOPHENYL) 2H TETRAZOLIUM 5 CARBOXANILIDE; 5 FLUORO 2 METHOXY N (2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 3 YL)BENZAMIDE; A 33903; A 58175; A 58568; A 58569; A 62066; ANILIDE; ANTIVIRUS AGENT; BENZAMIDE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; N (2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 3 YL)ACETAMIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEP 2 CELL; HUMAN; HUMAN CELL; IC 50; LIQUID CHROMATOGRAPHY; LOWER RESPIRATORY TRACT INFECTION; MULTIPLE SCLEROSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; REACTION ANALYSIS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; STRUCTURE ANALYSIS; VIRUS INFECTION;

ANIMALS; ANTIVIRAL AGENTS; BENZODIAZEPINES; CELL LINE, TUMOR; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; PLAQUE ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY SYNCYTIAL VIRUSES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645681649     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm051185t     Document Type: Article

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