Effects of latanoprost and GLC756, a novel dopamine D2 agonist and D1 antagonist, on cultured normal human dermal fibroblasts

European Journal of Ophthalmology

Volumn 16, Issue 1, 2006, Pages 67-72

  Laengle, U W ^a   Markstein, R ^b   Pralet, D ^a   Greiner, B ^a   Roman, D ^a,b  

^a Department of Toxicology/Pathology ^*  (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

D1 antagonist; D2 agonist; In vitro model; Latanoprost; Normal human dermal fibroblasts; Topical glaucoma medication

Indexed keywords

ANTIGLAUCOMA AGENT; BROXURIDINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 2 RECEPTOR STIMULATING AGENT; FLUOROURACIL; GLC 756; LATANOPROST; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECT; FIBROBLAST CULTURE; FILTERING OPERATION; GLAUCOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SCAR FORMATION;

EID: 33645550873     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067210601600112     Document Type: Article

References (36)

1. Ziai N, Dolan JW, Kacere RD, Brubaker RF. The effects on aqueous dynamics of PhXA41, a new prostaglandin F2 alpha analogue, after topical application in normal and ocular hypertensive human eyes. Arch Ophthalmol 1993; 111: 1351-8.
2. Alm A, Stjernschantz J. Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning. A comparison with timolol. Scandinavian Latanoprost Study Group. Ophthalmology 1995; 102: 1743-52.
3. 2 agonist, SDZ GLC 756, lowers intraocular pressure in healthy human volunteers and in patients with glaucoma. Ophthalmology 1995; 102: 1291-7.
4. Prünte C, Flammer J, Markstein R, Rudin M. Quantification of optic nerve blood flow using MR-imaging. Invest Ophthalmol Vis Sci 1995; 36: 247-51.
5. Chiou GC, Chen YJ. Effects of dopamine agonist, bromocriptine, and some dopamine antagonists on ocular blood flow. J Ocul Pharmacol 1992; 8: 285-94.
6. 2 receptors. J Neural Transm 1996; 103: 17-30.
7. Prünte C, Nuttli I, Markstein R. Topical SDZ GLC-756, a novel dopamine D-1 antagonist and D-2 agonist, lowers intraocular pressure in conscious rabbits. Jpn J Ophthalmol 1996; 40: 167-73.
8. Sherwood MB, Grierson I, Millar L, Hitchings RA. Long-term morphologic effects of antiglaucoma drugs on the conjunctiva and Tenon's capsule in glaucomatous patients. Ophthalmology 1989; 96: 327-35.
9. Maumenee AE. External filtering operations for glaucoma: the mechanism of function and failure. Trans Am Ophthalmol Soc 1960; 58: 319-28.
10. Flaxel JT, Swan KC. Limbal wound healing after cataract extraction. Arch Ophthalmol 1969; 81: 653-9.
11. Miller MH, Grierson I, Unger WI, Hitchings RA. Wound healing in an animal model of glaucoma fistulizing surgery in the rabbit. Ophthalmic Surg 1989; 20: 350-7.
12. Addicks EM, Quigley HA, Greene WR, Robin AL. Histologic characteristics of filtering blebs in glaucomatous eyes. Arch Ophthalmol 1983; 101: 795-8.
13. Broadway DC, Grierson I, O'Brien C, Hitchings RA. Adverse effects of topical antiglaucoma medication. II. The outcome of filtration surgery. Arch Ophthalmol 1994; 112: 1446-53.
14. Lavin MJ, Wormald RP, Migdal CS, Hitchings RA. The influence of prior therapy on the success of trabeculectomy. Arch Ophthalmol 1990; 108: 1543-8.
15. Young TL, Higginbotham EJ, Zou XL, Farber MD. Effects of topical glaucoma drugs on fistulized rabbit conjunctiva. Ophthalmology 1990; 97: 1423-7.
16. Lark KK, Pasha AS, Yan X, Edward DP. The effect of latanoprost and brimonidine on rabbit subconjunctival fibroblasts. J Glaucoma 1999; 8: 72-6.
17. Williams DE, Nguyen KD, Shapourifar-Tehrani S, Kitada S, Lee DA. Effects of timolol, betaxolol, and levobunolol on human Tenon's fibroblasts in tissue culture. Invest Ophthalmol Vis Sci 1992; 33: 2233-41.
18. Cunliffe IA, McIntyre CA, Rees RC, Rennie IG. The effect of topical cholinergic medications on human Tenon's capsule fibroblasts in tissue culture. Graefes Arch Clin Exp Ophthalmol 1995; 233: 507-12.
19. Cunliffe IA, McIntyre CA, Rees RC, Rennie IG. Pilot study on the effect of topical adrenergic medications on human Tenon's capsule fibroblasts in tissue culture. Br J Ophthalmol 1995; 79: 70-5.
20. Wu KY, Hong SJ, Wang HZ. Effects of pilocarpine and other antiglaucoma drugs on cultured human Tenon's fibroblast cells. J Ocul Pharmacol Ther 1997; 13: 13-20.
21. Wu KY, Hong SJ, Chung YM. Effects of dopamine antagonists and agonist on cultured human Tenon's fibroblast cells. Kaohsiung J Med Sci 1996; 12: 388-93.
22. Kamentsky LA, Burger DE, Gershman RJ, Kamentsky LD, Luther E. Slide-based laser scanning cytometry. Acta Cytologica 1997; 41: 123-43.
23. Ariturk N, Oge I., Baris S, Erkan D, Sullu Y, Koc F. The effects of antiglaucomatous agents on conjunctiva used for various durations. Int Ophthalmol 1997; 20: 57-62.
24. Broadway DC, Grierson I., O'Brien C, Hitchings RA. Adverse effects of topical antiglaucoma medication. I. The conjunctival cell profile. Arch Ophthalmol 1994; 112: 1437-45.
25. Kellett M, Potten CS, Rew DA. A comparison of in vivo cell proliferation measurements in the intestine of mouse and man. Epithelial Cell Biol 1992; 1: 147-55.
26. Heuer DK, Parrish RK, Gressel MG, Hodapp E, Palmberg PF, Anderson DR. 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. Ophthalmology 1984; 91: 384-94.
27. Rockwood EJ, Parrish RK, Heuer DK, et al. Glaucoma filtering surgery with 5-fluorouracil. Ophthalmology 1987; 94: 1071-8.
28. Durant S, Duval D, Homo-Delarche F. Effect of exogenous prostaglandins and nonsteroidal anti-inflammatory agents on prostaglandin secretion and proliferation of mouse embryo fibroblasts in culture. Prostaglandins Leukotrienes Essential Fatty Acids 1989; 38: 1-8.
29. De Asura LJ, Clingan D, Rudland PS. Initiation of cell proliferation in cultured mouse fibroblasts by prostaglandin F2?. Proc Natl Acad Sci USA 1975; 72: 2724-8.
30. Ko SD, Page RC, Narayanan AS. Fibroblast heterogeneity and prostaglandin regulation of subpopulations. Proc Natl Acad Sci USA 1977; 74: 3429-32.
31. Korn JH, Halushka PV, Leroy EC. Mononuclear cell modulation of connective tissue function. Suppression of fibroblast growth by stimulation of endogenous prostaglandin production. J Clin Invest 1980; 65: 543-54.
32. Ali AE, Barrett JC, Eling TE. Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. Prostaglandins 1980; 20: 667-88.
33. Durant S, Duval D, Homo-Delarche F. Mouse embryo fibroblasts in culture: characteristics of arachidonic acid metabolism during early passages. Prostaglandins Leukotrienes Essential Fatty Acids 1988; 32: 129-37.
34. Warwar RE, Bullock JD, Ballal D. Cystoid macular edema and anterior uveitis associated with latanoprost use. Experience and incidence in a retrospective review of 94 patients. Ophthalmology 1998; 105: 263-8.
35. Anand N, Sahni K, Menage MJ. Modification of trabeculectomy with single-dose intraoperative 5- fluorouracil application. Acta Ophthalmol Scand 1998; 76: 83-9.
36. Khaw PT, Doyle JW, Sherwood MB, Smith MF, McGorray S. Effects of intraoperative 5-fluorouracil or mitomycin C on glaucoma filtration surgery in the rabbit. Ophthalmology 1993; 100: 367-72.