Local anesthetic-induced protection against lipopolysaccharide-induced injury in endothelial cells: The role of mitochondrial adenosine triphosphate-sensitive potassium channels

Anesthesia and Analgesia

Volumn 102, Issue 4, 2006, Pages 1108-1113

  De Klaver, Manuela J M ^b   Weingart, Gregory S ^b   Obrig, Tom G ^b   Rich, George F ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; BUPIVACAINE; DIAZOXIDE; FLAVOPROTEIN; LIDOCAINE; LIPOPOLYSACCHARIDE; LOCAL ANESTHETIC AGENT; PROCAINE; ROPIVACAINE; TETRACAINE;

ANESTHESIA MECHANISM; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LOCAL ANESTHESIA; MITOCHONDRION; PRIORITY JOURNAL;

EID: 33645531793     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000200310.39031.1f     Document Type: Article

References (24)

1. Rodgers A, Walker N, Schug S, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ 2000;321:1493.
2. Kamiyama T, Tanonaka K, Harada H, et al. Mexiletine and lidocaine reduce post-ischemic functional and biochemical dysfunction of perfused hearts. Eur J Pharmacol 1995;272:151-8.
3. Lee R, Nitta T, Schmid RA, et al. Retrograde infusion of lidocaine or L-arginine before reperfusion reduces myocardial infarct size. Ann Thorac Surg 1998;65:1353-9.
4. Peck SL, Johnston RB, Horwitz LD. Reduced neutrophil superoxide anion release after prolonged infusion of lidocaine. J Pharmacol Exp Ther 1985;235:418-22.
5. Sinclair R, Eriksson AS, Gretzer C, et al. Inhibitory effects of amide local anaesthetics on stimulus induced human leukocyte metabolic activation, LTB4 release and IL-1 secretion in vitro. Acta Anaesthesiol Scand 1993;37:159-65.
6. Sultan I, Sunamori M, Suzuki A. Heart preservation: analysis of cardioprotective infusate characteristics: membrane stabilization, calcium antagonism, and protease inhibition on myocardial viability: a biochemical, ultrastructural, functional study. J Heart Lung Transplant 1992;11:607-18.
7. +) overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection. Circ Res 2001;89:891-8.
8. Kohro S, Hogan QH, Nakae Y, et al. Anesthetic effects on mitochondrial ATP-sensitive K channel. Anesthesiology 2001;95:1435-40.
9. Nakae Y, Kohro S, Hogan QH, Bosnjak ZJ. Intracellular mechanism of mitochondrial adenosine triphosphate-sensitive potassium channel activation with isoflurane. Anesth Analg 2003;97:1025-32.
10. De Klaver M, Buckingham M-G, Rich G. Lidocaine attentuates cytokine-induced injury in endothelial and vascular smooth muscle cells. Anesth Analg 2003;97:465-70.
11. Strichartz GR, Sanchez V, Arthur GR, et al. Fundamental properties of local anesthetics. II. Measured octanol:buffer partition coefficients and pKa values of clinically used drugs. Anesth Analg 1990;71:158-70.
12. Rabinovitch M, DeStefano MJ. Cell shape changes induced by cationic anesthetics. J Exp Med 1976;143:290-304.
13. Rabinovitch M, DeStefano M. Cell to substrate adhesion and spreading: inhibition by cationic anesthetics. J Cell Physiol 1975;85:189-93.
14. Hahnenkamp K, Herroeder S, Hollmann MW. Regional anaesthesia, local anaesthetics and the surgical stress response. Best Pract Res Clin Anaesthesiol 2004;18:509-27.
15. Hollmann MW, Wieczorek KS, Berger A, Durieux ME. Local anesthetic inhibition of G protein-coupled receptor signaling by interference with G alpha(q) protein function. Mol Pharmacol 2001;59:294-301.
16. Goldstein IM, Lind S, Hoffstein S, Weissmann G. Influence of local anesthetics upon human polymorphonuclear leukocyte function in vitro. J Exp Med 1977;146:883-94.
17. Hollmann MW, Durieux ME. Local anesthetics and the inflammatory response: a new therapeutic indication. Anesthesiology 2000;93:858-75.
18. Tsutsumi Y, Oshita S, Kawano T. Lidocaine and mexiletine inhibit mitochondrial oxidation in rat ventricular myocytes. Anesthesiology 2001;95:766-70.
19. Kang MY, Tsuchiya M, Packer L, Manabe M. In vitro study on antioxidant potential of various drugs used in the perioperative period. Acta Anaesthesiol Scand 1998;42:4-12.
20. Mikawa K, Akamatsu H, Nishina K, et al. Inhibitory effect of local anaesthetics on reactive oxygen species production by human neutrophils. Acta Anaesthesiol Scand 1997;41:524-8.
21. Dos Santos P, Kowaltowski AJ, Laclau MN, et al. Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart. Am J Physiol Heart Circ Physiol 2002;283:H284-95.
22. 2 and NO concentrations in NO-induced cell death in a rat liver sinusoidal endothelial cell line. Biol Chem 2004;385:341-9.
23. Pino P, Vouldoukis I, Dugas N, et al. Redox-dependent apoptosis in human endothelial cells after adhesion of Plasmodium falciparum-infected erythrocytes. Ann N Y Acad Sci 2003;1010:582-6.
24. Lien YH, Lai LW, Silva AL. Pathogenesis of renal ischemia/ reperfusion injury: lessons from knockout mice. Life Sci 2003;74:543-52.