Thymus and myasthenia gravis: Antigen processing in the human thymus and the consequences for the generation of autoreactive T cells

Acta Neurologica Scandinavica

Volumn 113, Issue SUPPL. 183, 2006, Pages 12-13

  Melms, A ^a   Luther, C ^a   Stoeckle, C ^a   Poschel S ^a   Schroth, P ^a   Varga, M ^a   Wienhold, W ^a   Tolosa, E ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Antigen processing; Cathepsin; Myasthenia gravis; Proteases; Thymus

Indexed keywords

CATHEPSIN; CATHEPSIN V; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEINASE; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; HLA ANTIGEN CLASS 2;

ANTIGEN PRESENTATION; CD4+ T LYMPHOCYTE; CONFERENCE PAPER; GENE OVEREXPRESSION; HELPER CELL; HUMAN; LYMPHOID TISSUE; LYSOSOME; MYASTHENIA GRAVIS; T LYMPHOCYTE; THYMOMA; THYMUS; ANTIGEN PRESENTING CELL; ENZYMOLOGY; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; REVIEW;

ANTIGEN-PRESENTING CELLS; CATHEPSINS; CD4-POSITIVE T-LYMPHOCYTES; CYSTEINE ENDOPEPTIDASES; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MYASTHENIA GRAVIS; THYMUS GLAND;

EID: 33645529302     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2006.00636.x     Document Type: Conference Paper

References (1)

1. T olosa E L i W W ienhold W D enzin LK S tevanovic S D riessen C S chnorrer P W eber E K urek R M elms A B römme D. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest 2003 112 517 526.