Peptide and peptide-like modulators of 20S proteasome enzymatic activity in cancer cells

International Journal of Peptide Research and Therapeutics

Volumn 12, Issue 1, 2006, Pages 49-64

  García Echeverría, Carlos ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Anticancer agents; Drug design; Enzyme inhibitors; Irreversible inhibitors; Peptidomimetics; Reversible inhibitors; Suicide inhibitors

Indexed keywords

5 METHOXY 1 INDANONE DIPEPTIDE BENZAMIDE DERIVATIVE; ACETYLLEUCYLLEUCYLMETHIONINAL; ACETYLLEUCYLLEUCYLNORLEUCINAL; ALDEHYDE DERIVATIVE; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; BORTEZOMIB; CALPASTATIN; CEP 1612; CVT 634; CVT 659; DIHYDROEPONEMYCIN; EPOXOMICIN; ETOPOSIDE; FLUOROURACIL; GEMCITABINE; KF 33955; LACTACYSTIN; LACTACYSTIN BETA LACTONE; MG 167; NATURAL PRODUCT; NPI 0052; PEPTIDE DERIVATIVE; PR 39; PROTEASOME; PROTEASOME 20S; PROTEASOME 20S INHIBITOR; PROTEASOME INHIBITOR; SALINOSPORAMIDE A; TMC 95A; TMC 95B; TMC 95C; TMC 95D; TP 110; TRYOPEPTIN A; UBIQUITIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINYL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; CANCER; CANCER MODEL; CLINICAL TRIAL; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; NONHUMAN; PERIPHERAL NEUROPATHY; PROTEIN DEGRADATION; PROTEIN FUNCTION; REVIEW; STRUCTURE ANALYSIS;

EID: 33645471039     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-005-9001-4     Document Type: Review

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