Glycolipid receptor depletion as an approach to specific antimicrobial therapy

FEMS Microbiology Letters

Volumn 258, Issue 1, 2006, Pages 1-8

  Svensson, Majlis ^a   Platt, Frances M ^b   Svanborg, Catharina ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Antimicrobial therapy; Glycosyltransferase inhibitors; Receptor depletion; Urinary tract infection

Indexed keywords

ALPHA DEXTRO MANNOPYRANOSIDE; ANTIINFECTIVE AGENT; BACTERIAL VACCINE; CARBOHYDRATE; GANGLIOSIDE GM1; GLUCOSYLCERAMIDASE; GLYCOSPHINGOLIPID SYNTHESIS INHIBITOR; MIGLUSTAT; PYRANOSIDE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTIMICROBIAL THERAPY; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIURIA; CARBOHYDRATE SYNTHESIS; DISEASE PREDISPOSITION; DRUG EFFECT; DRUG INHIBITION; DRUG RECEPTOR BINDING; DRUG TARGETING; EXPERIMENTAL INFECTION; FABRY DISEASE; FIMBRIA; GAUCHER DISEASE; GENETIC DISORDER; GLYCOSYLATION; HUMAN; INFECTION PREVENTION; INNATE IMMUNITY; LIPIDOSIS; LIVER HYPERTROPHY; MUCOSAL IMMUNITY; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; SHORT SURVEY; SPECIES COMPARISON; SPLENOMEGALY; TAY SACHS DISEASE; URINARY TRACT INFECTION; UROPATHOGENIC ESCHERICHIA COLI; VIBRIO CHOLERAE;

1-DEOXYNOJIRIMYCIN; ANIMALS; BACTERIAL ADHESION; ESCHERICHIA COLI INFECTIONS; GLYCOSPHINGOLIPIDS; HUMANS; IMMUNITY, NATURAL; LYSOSOMAL STORAGE DISEASES; RECEPTORS, CELL SURFACE; URINARY TRACT INFECTIONS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; VIBRIO CHOLERAE;

EID: 33645464234     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2006.00175.x     Document Type: Short Survey

References (61)

1. Abe A Gregory S Lee L Killen PD Brady RO Kulkarni A Shayman JA 2000 Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation J Clin Invest 105 1563 1571
2. Agace W Hedges S Svanborg C 1992 IL-8 production by urinary tract epithelial cell lines Recent Advances in Mucosal Immunology McGhee J Mestecky J Tlaskalova H Sterzl J eds) Plenum Press New York
3. Agace WW Hedges SR Ceska M Svanborg C 1993 Interleukin-8 and the neutrophil response to mucosal gram-negative infection J Clin Invest 92 780 785
4. Aronson M Medalia O Schori L Mirelman D Sharon N Ofek I 1979 Prevention of colonisation of the urinary tract of mice with Escherichia coli by blocking of bacterial adherence with methyl α- d -manno-pyranoside J Infect Dis 139 329
5. Bergsten G Samuelsson M Wullt B Leijonhufvud I Fischer H Svanborg C 2004 PapG-dependent adherence breaks mucosal inertia and triggers the innate host response J Infect Dis 189 1734 1742
6. Bock K Breimer M Brignole A et al 1985 Specificity of binding of a strain of uropathogenic Escherichia coli to Gala1-4Galb-containing glycosphingolipids J Biol Chem 260 8545 8551
7. Cox T Lachmann R Hollak C et al 2000 Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis Lancet 355 1481 1485
8. Duguid JP Gillies RR 1957 Fimbriae and adhesive properties in dysenteric bacilli J Pathol Bacteriol 74 397 411
9. Elstein D Hollak C Aerts JM et al 2004 Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease J Inherit Metab Dis 27 757 766
10. Evans DG Evans DJJ Sack DA Clegg S 1984 Enterotoxigenic Escherichia coli pathogenic for man biological and immunological aspects of fimbrial colonization factor antigen Attachment of organisms to the gut mucosa Vol. I Boedeker EC ed), pp. 63 77 CRC Press Boca Raton, FL
11. Fischer H Yamamoto M Akira S Beutler B Svanborg C 2005 Mechanism of pathogen specific TLR4 activation and adaptor protein selection Eur J Immunol 36 267 277
12. Frendeus B Wachtler C Hedlund M Fischer H Samuelsson P Svensson M Svanborg C 2001 Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation Mol Microbiol 40 37 51
13. Freter R 1969 Studies on the mechanism of action of intestinal antibody in experimental cholera Texas Rep Biol Med 27 299 316
14. Godaly G Frendéus B Prodfoot A Svensson M Klemm P Svanborg C 1998 Role of fimbriae-mediated adherence for neutrophil migration across Escherichia coli-infected epithelial cell layers Mol Microb 30 725 735
15. Hagberg L Engberg I Freter R Lam J Olling S Svanborg-Edén C 1983 Ascending, unobstructed urinary tract infection in mice caused by pyelonephritogenic Escherichia coli of human origin Infect Immun 40 273 283
16. Hang L Haraoka M Agace WW Leffler H Burdick M Strieter R Svanborg C 1999 Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract J Immunol 162 3037 3044
17. Haraoka M Hang L Frendeus B Godaly G Burdick M Strieter R Svanborg C 1999 Neutrophil recruitment and resistance to urinary tract infection J Infect Dis 180 1220 1229
18. Hedges S de Man P Linder H van Kooten C Svanborg-Edén C 1990 Interleukin-6 is secreted by epithelial cells in response to Gram-negative bacterial challenge Advances in Mucosal Immunology. International Conference of Mucosal Immunity Macdonald T ed), pp. 144 148 Kluwer London
19. Hedges S Bjarndottir M Agace W Hang L Svanborg C 1996 Immunoregulatory cytokines modify Escherichia coli induced uroepithelial cell IL-6 and IL-8 responses Cytokine 8 686 697
20. van Heyningen WE King CA 1976 The role of gangliosides in the action of cholera toxin Adv Exp Med Biol 71 205 214
21. Holgersson J Breimer ME Samuelsson BE 1992 Basic biochemistry of cell surface carbohydrates and aspects of the tissue distribution of histo-blood group ABH and related glycosphingolipids APMIS 100 18 27
22. Inokuchi J Radin NS 1987 Preparation of the active isomer of 1-phenyl-2-decanoylomino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase J Lipid Res 28 565 571
23. Inokuchi J Mason I Radin NS 1987 Antitumor activity via inhibitor of glycosphingolipid biosynthesis Cancer Lett 38 23 30
24. Inokuchi J Momosaki K Shimeno H Nagamatsu A Radin NS 1989 Effects of d -threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells J Cell Physiol 141 573 583
25. Jeyakumar M Butters TD Cortina-Borja M Hunnam V Proia RL Perry VH Dwek RA Platt FM 1999 Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin Proc Natl Acad Sci USA 96 6388 6393
26. Källenius G Möllby R Winberg J Lundblad S Svensson S Cedergren B 1980 The Pk antigen as a receptor for the hemaglutination of pyelonephritogenic Escherichia coli FEMS Microbiol Lett 7 297 302
27. Korhonen TK Parkkinen J Hacker J Finne J Pere A Rhen M Holthofer H 1986 Binding of Escherichia coli S fimbriae to human kidney epithelium Infect Immun 54 322 327
28. Leffler H Svanborg-Edén C 1980 Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary tract epithelial cells and agglutinating human erythrocytes FEMS Microbiol Lett 8 127 134
29. Lindberg F Lund B Normark S 1984 Genes of pyelonephritogenic Escherichia coli required for digalactoside specific agglutination of human cells EMBO J 3 1167 1173
30. Lindberg B Lund B Normark S 1986 Gene products specifying adhesion of uropathogenic Escherichia coli are minor components of pili Proc Natl Acad Sci USA 83 1891 1895
31. Lingwood CA Boyd B Nutikka A 2000 Analysis of interactions between glycosphingolipids and microbial toxins Methods Enzymol 312 459 473
32. Lomberg H Jodal U Svanborg-Edén C Leffler H Samuelsson B 1981 P1 blood group and urinary tract infection Lancet i 551 552
33. Lomberg H Cedergren B Leffler H Nilsson B Carlström A-S Svanborg-Edén C 1986 Influence of blood group on the availability of receptors for attachment of uropathogenic Escherichia coli Infect Immun 51 919 926
34. Lund B Lindberg F Marklund B Normark S 1987 The pap G protein is the α- d -galactopyranosyl-(1-4)-β- d -galactopyranose-binding adhesin of uropathogenic Escherichia coli Proc Natl Acad Sci USA 84 5898 5902
35. Marasas WF Riley RT Hendricks KA et al 2004 Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize J Nutr 134 711 716
36. Marcus D Kundu S Suguki A 1981 The P blood group system recent progress in immunochemistry and genetics Semin Hematol 18 63 71
37. Mirelman D (ed) 1986 Microbial Lectins and Agglutinins: Properties and Biological Activity John Wiley and Sons New York
38. Norred WP Wang E Yoo H Riley RT Merrill AH Jr. 1992 In vitro toxicology of fumonisins and the mechanistic implications Mycopathologia 117 73 78
39. Ofek I Mirelman D Sharon N 1977 Adherence of Escherichia coli to human mucosal cells mediated by mannose receptors Nature 265 623 625
40. Platt F Reinkensmeier G Dwek RA Butters T 1997 Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin J Biol Chem 272 19365 19372
41. Platt F Butters T 1995 Inhibitors of glycosphingolipid biosynthesis Trends Glycosci Glycotechnol 7 495 511
42. Platt F Butters TD 1998 New therapeutic prospects for the glycosphingolipid lysosomal storage diseases Biochem Pharmcol 15 421 430
43. Platt F Butters TD 2004 Inhibition of substrate synthesis; a pharmacological approach for glycosphingolipid storage disease therapy Lysosomal Disorders of Brain Walkley FMPaSU ed) Oxford University Press Oxford
44. Platt F Neises R Dwek RA Butters T 1994a N-Butyldeoxinojirimycine is a novel inhibitor of glycolipid biosynthesis J Biol Chem 269 8362 8365
45. Platt FM Neises GR Karlsson GB Dwek RA Butters TD 1994b N-butyldeoxygalactonojirimycin inhibits glycolipid biosynthesis but does not affect N-linked oligosaccharide processing J Biol Chem 269 27108 27114
46. Platt F Neises R Dwek RA et al 1997 Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin Science 276 428 431
47. Radin NS 1984 Biosynthesis of the sphingoid bases a provocation J Lipid Res 25 1536 1540
48. Radin NS Shayman JA Inokuchi J 1993 Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances Adv Lipid Res 26 183 213
49. Scharfman A Van Brussel E Houdret N Lamblin G Roussel P 1996 Interactions between glycoconjugates from human respiratory airways and Pseudomonas aeruginosa Am J Respir Crit Care Med 154 S163 S169
50. Shahin RD Engberg I Hagberg L Svanborg-Eden C 1987 Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection J Immunol 138 3475 3480
51. Shayman JA Radin NS 1991 Structure and function of renal glycosphingolipids Am J Physiol 260 F291 F302
52. Stapleton A Nudelman E Clausen H Hakomori S Stamm WE 1992 Binding of uropathogenic Escherichia coli R45 to glycolipids extracted from vaginal epithelial cells is dependent on histo-blood group secretor status J Clin Invest 90 965 972
53. Svanborg-Edén C Svennerholm AM 1978 Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells Infect Immun 22 790 797
54. Svanborg-Eden C Hansson L 1980 Glycosphingolipids of human urinary tract epithelial cells as possible receptors for adhering Escherichia coli bacteria Scand J Infect Dis Suppl 24 144 147
55. Svanborg-Edén C Hanson L Jodal U Lindberg U Sohl-Åkelund A 1976 Variable adherence to normal urinary tract epithelial cells of Escherichia coli strains associated with various forms of urinary tract infection Lancet 1 490 492
56. Svanborg-Edén C Freter R Hagberg L Hull R Hull S Leffler H Schoolnik G 1982 Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue Nature (London) 298 560 562
57. Svensson M Lindstedt R Radin N Svanborg C 1994 Epithelial glycosphingolipid expression as a determinant of bacterial adherence and cytokine production Infect Immun 62 4404 4410
58. Svensson M Frendeus B Butters T Platt F Dwek R Svanborg C 2003 Glycolipid depletion in antimicrobial therapy Mol Microbiol 47 453 461
59. Takala AK Santosham M Almeido-Hill J Wolff M Newcomer W Reid R Kayhty H Esko E Makela PH 1993 Vaccination with Haemophilus influenzae type b meningococcal protein conjugate vaccine reduces oropharyngeal carriage of Haemophilus influenzae type b among American Indian children Pediatr Infect Dis J 12 593 599
60. Williams RC Gibbons RJ 1972 Inhibition of bacterial adherence by secretory immunoglobulin A a mechanism of antigen disposal Science 177 697 699
61. Wullt B Bergsten G Connell H Rollano P Gebratsedik N Hang L Svanborg C 2001 P-fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract Cell Microbiol 3 255 264