Development of cyclic γ-MSH analogues with selective hHMC3R agonist and hMC3R/hMC5R antagonist activities

Journal of Medicinal Chemistry

Volumn 49, Issue 6, 2006, Pages 1946-1952

  Mayorov, Alexander V ^a   Cai, Minying ^a   Chandler, Kevin B ^a   Petrov, Ravil R ^a   Van Scoy, April R ^a   Yu, Zerui ^a   Tanaka, Dustin K ^a   Trivedi, Dev ^a   Hruby, Victor J ^a  

^a University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN DERIVATIVE; MELANOCORTIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR;

ARTICLE; DRUG DESIGN; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; PHARMACOPHORE; SOLID PHASE SYNTHESIS; STEREOCHEMISTRY;

ADENYLATE CYCLASE; BINDING, COMPETITIVE; CELL LINE; DRUG DESIGN; GAMMA-MSH; HUMANS; HYDROPHOBICITY; LACTAMS; MODELS, MOLECULAR; PEPTIDES, CYCLIC; RADIOLIGAND ASSAY; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTORS, CORTICOTROPIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645458748     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0510326     Document Type: Article

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