CV-11974, angiotensin II type I receptor antagonist, protects against ischemia-reperfusion injury of the small intestine in rats

European Journal of Pharmacology

Volumn 535, Issue 1-3, 2006, Pages 283-290

  Takagi, Tomohisa ^a   Yoshida, Norimasa ^a   Isozaki, Yutaka ^a   Shimozawa, Makoto ^a   Katada, Kazuhiro ^a   Manabe, Hiroki ^a   Hanada, Osamu ^a   Kokura, Satoshi ^a   Ichikawa, Hiroshi ^a   Naito, Yuji ^a   Okanoue, Takeshi ^a   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Angiotensin II type I receptor antagonist; Intestinal injury; Ischemia; Reperfusion

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BIOCHEMICAL MARKER; CANDESARTAN; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; HEMOGLOBIN; MESSENGER RNA; MYELOPEROXIDASE; THIOBARBITURIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOXIA; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INTESTINE INJURY; INTESTINE MUCOSA; ISCHEMIA; LIPID PEROXIDATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; STOMACH MUCOSA; SUPERIOR MESENTERIC ARTERY;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; CELL ADHESION; CELL LINE; CHEMOKINES, CXC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION; HEMOGLOBINS; HUMANS; INTESTINAL DISEASES; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; NEUTROPHILS; PEROXIDASE; PROTEINS; RATS; RATS, WISTAR; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 33645452137     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.02.005     Document Type: Article

References (47)

1. H. Ando, J. Zhou, M. Macova, H. Imboden, and J.M. Saavedra Angiotensin II AT1 receptor blockade reverses pathological hypertrophy and inflammation in brain microvessels of spontaneously hypertensive rats Stroke 35 2004 1726 1731
2. J. Araya, T. Tsuruma, K. Hirata, A. Yagihashi, and N. Watanabe TCV-116, an angiotensin II type 1 receptor antagonist, reduces hepatic ischemia-reperfusion injury in rats Transplantation 73 2002 529 534
3. C. Bregonzio, I. Armando, H. Ando, M. Jezova, G. Baiardi, and J.M. Saavedra Angiotensin II AT1 receptor blockade prevents gastric ulcers during cold-restraint stress Ann. N. Y. Acad. Sci. 1018 2004 351 355
4. M. Burnier, and H.R. Brunner Angiotensin II receptor antagonists Lancet 355 2000 637 645
5. V. da Cunha, D.M. Tham, B. Martin-McNulty, G. Deng, J.J. Ho, D.W. Wilson, J.C. Rutledge, R. Vergona, M.E. Sullivan, and Y.X. Wang Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation Atherosclerosis 178 2005 9 17
6. P. Dandona, V. Kumar, A. Aljada, H. Ghanim, T. T. Syed, D. Hofmayer, P. Mohanty, D. Tripathy, and R. Garg Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action J. Clin. Endocrinol. Metab. 88 2003 4496 4501
7. V.J. Dzau, G.H. Gibbons, and R.E. Pratt Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia Hypertension 18 1991 II100 II105
8. R. El Bekay, M. Alvarez, J. Monteseirin, G. Alba, P. Chacon, A. Vega, J. Martin-Nieto, J. Jimenez, E. Pintado, F.J. Bedoya, and F. Sobrino Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of mitogen-activated protein kinase, calcineurin, and the transcription factor NF-kappaB Blood 102 2003 662 671
9. T. Engelhorn, S. Goerike, A. Doerfler, C. Okorn, M. Forsting, G. Heusch, and R. Schulz The angiotensin II type 1-receptor blocker candesartan increases cerebral blood flow, reduces infarct size, and improves neurologic outcome after transient cerebral ischemia in rats J. Cereb. Blood Flow Metab. 24 2004 467 474
10. R. Estelles, J. Lopez-Martin, L. Milian, J.E. O'Connor, M. Martinez-Losa, M. Cerda-Nicolas, E.M. Anam, M.D. Ivorra, A.C. Issekutz, J. Cortijo, E.J. Morcillo, M.A. Blazquez, and M.J. Sanz Effect of two phenanthrene alkaloids on angiotensin II-induced leukocyte-endothelial cell interactions in vivo Br. J. Pharmacol. 140 2003 1057 1067
11. J.M. Good, P. Nihoyannopoulos, M.A. Ghatei, D. Crossman, S.R. Bloom, P. Clark, C.M. Oakley, and J.G. Cleland Elevated plasma endothelin concentrations in heart failure; an effect of angiotensin II Eur. Heart J. 15 1994 1634 1640
12. D.N. Granger Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury Am. J. Physiol. 255 1988 H1269 H1275
13. D.N. Granger, G. Rutili, and J.M. McCord Superoxide radicals in feline intestinal ischemia Gastroenterology 81 1981 22 29
14. M.B. Grisham, L.A. Hernandez, and D.N. Granger Xanthine oxidase and neutrophil infiltration in intestinal ischemia Am. J. Physiol. 251 1986 G567 G574
15. W. Groth, A. Blume, P. Gohlke, T. Unger, and J. Culman Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats J. Hypertens. 21 2003 2175 2182
16. L.A. Hernandez, M.B. Grisham, B. Twohig, K.E. Arfors, J.M. Harlan, and D.N. Granger Role of neutrophils in ischemia-reperfusion-induced microvascular injury Am. J. Physiol. 253 1987 H699 H703
17. T. Ito, Y. Nishimura, and J. Saavedra Pre-treatment with candesartan protects from cerebral ischaemia J. Renin-Angiotensin-Aldosterone Syst. 2 2001 174 179
18. M. Itoh, and P.H. Guth Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat Gastroenterology 88 1985 1162 1167
19. S. Kokura, N. Yoshida, E. Imamoto, M. Ueda, T. Ishikawa, K. Uchiyama, M. Kuchide, Y. Naito, T. Okanoue, and T. Yoshikawa Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines Cancer Lett. 211 2004 79 87
20. S.E. Kong, L.R. Blennerhassett, K.A. Heel, R.D. McCauley, and J.C. Hall Ischaemia-reperfusion injury to the intestine Aust. N.Z. J. Surg. 68 1998 554 561
21. M.A. Konstam Role of angiotensin converting enzyme inhibitors in preventing left ventricular remodelling following myocardial infarction Eur. Heart J. 16 Suppl 1995 42 48
22. I. Kusaka, G. Kusaka, C. Zhou, M. Ishikawa, A. Nanda, D.N. Granger, J.H. Zhang, and J. Tang Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury Am. J. Physiol, Heart Circ. Physiol. 286 2004 H2442 H2451
23. M.B. Lawrence, L.V. McIntire, and S.G. Eskin Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion Blood 70 1987 1284 1290
24. O.H. Lowry, N.J. Rosenbrough, A.L. Farr, and R.J. Randall Protein measurement with the folin phenol reagent J. Biol. Chem. 193 1951 265 275
25. H. Masuko, M.B. Jin, H. Horiuchi, T. Suzuki, M. Taniguchi, T. Shimamura, M. Fukai, S. Magata, K. Ogata, H. Ishikawa, M. Fujita, K. Nagashima, H. Furukawa, and S. Todo Protective effect of agiotensin II type I receptor antagonist, CV-11974, on ischemia and reperfusion injury of the liver Transplantation 71 2001 1034 1039
26. Y.N. Nabah, T. Mateo, R. Estelles, M. Mata, J. Zagorski, H. Sarau, J. Cortijo, E.J. Morcillo, P.J. Jose, and M.J. Sanz Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines Circulation 110 2004 3581 3586
27. L.G. Navar, P.K. Carmines, W.C. Huang, and K.D. Mitchell The tubular effects of angiotensin II Kidney Int., Suppl. 20 1987 S81 S88
28. U.A. Nilsson, M.H. Schoenberg, A. Aneman, B. Poch, S. Magadum, H.G. Beger, and O. Lundgren Free radicals and pathogenesis during ischemia and reperfusion of the cat small intestine Gastroenterology 106 1994 629 636
29. H. Ohkawa, N. Ohnishi, and K. Yagi Assay for lipid peroxides for animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1986 351 358
30. G. Paragh, J. Szabo, E. Kovacs, T. Keresztes, I. Karpati, Z. Balogh, D. Pall, and G. Foris Altered signal pathway in angiotensin II-stimulated neutrophils of patients with hypercholesterolaemia Cell Signal 14 2002 787 792
31. P.O. Park, U. Haglund, G.B. Bulkley, and K. Falt The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion Surgery 107 1990 574 580
32. D.A. Parks, and D.N. Granger Contributions of ischemia and reperfusion to mucosal lesion formation Am. J. Physiol. 250 1986 G749 G753
33. D.A. Parks, G.B. Bulkley, D.N. Granger, S.R. Hamilton, and J.M. McCord Ischemic injury in the cat small intestine: role of superoxide radicals Gastroenterology 82 1982 9 15
34. K. Przyklenk, and R.A. Kloner "Cardioprotection" by ACE-inhibitors in acute myocardial ischemia and infarction Basic Res. Cardiol. 88 Suppl 1 1993 139 154
35. S. Raiden, K. Nahmod, V. Nahmod, G. Semeniuk, Y. Pereira, C. Alvarez, M. Giordano, and J.R. Geffner Nonpeptide antagonists of AT1 receptor for angiotensin II delay the onset of acute respiratory distress syndrome J. Pharmacol. Exp. Ther. 303 2002 45 51
36. A.A. Riaz, Y. Wang, R. Schramm, T. Sato, M.D. Menger, B. Jeppsson, and H. Thorlacius Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon FASEB J. 18 2004 881 883
37. Y. Shibouta, Y. Inada, M. Ojima, T. Wada, M. Noda, T. Sanada, K. Kubo, Y. Kohara, T. Naka, and K. Nishikawa Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2′-(1H- tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl] -1H-benzimidazole-7-carboxylate (TCV-116) J. Pharmacol. Exp. Ther. 266 1993 114 120
38. A. Sigurdsson, P. Held, and K. Swedberg Short- and long-term neurohormonal activation following acute myocardial infarction Am. Heart J. 126 1993 1068 1076
39. D.G. Souza, R. Bertini, A.T. Vieira, F.Q. Cunha, S. Poole, M. Allegretti, F. Colotta, and M.M. Teixeira Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury Br. J. Pharmacol. 143 2004 132 142
40. E. Stenman, and L. Edvinsson Cerebral ischemia enhances vascular angiotensin AT1 receptor-mediated contraction in rats Stroke 35 2004 970 974
41. V. Timmermans, P.W. Peake, J.A. Charlesworth, G.J. Macdonald, and M.A. Pawlak Angiotensin II receptor regulation in anti-glomerular basement membrane nephritis Kidney Int. 38 1990 518 524
42. N. Tomatsuri, N. Yoshida, T. Takagi, K. Katada, Y. Isozaki, E. Imamoto, K. Uchiyama, S. Kokura, H. Ichikawa, Y. Naito, T. Okanoue, and T. Yoshikawa Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats Int. J. Mol. Med. 13 2004 105 109
43. N. Yoshida, D.N. Granger, D.C. Anderson, R. Rothlein, C. Lane, and P.R. Kvietys Anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells Am. J. Physiol. 262 1992 H1891 H1898
44. T. Yoshikawa, S. Ueda, Y. Naito, S. Takahashi, H. Oyamada, Y. Morita, T. Yoneta, and M. Kondo Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats Free Radic. Res. Commun. 7 1989 285 291
45. B.J. Zimmerman, and D.N. Granger Mechanisms of reperfusion injury Am. J. Med. Sci. 307 1994 284 292
46. K. Watanabe, K. Konishi, M. Fujioka, S. Kinoshita, and H. Nakagawa The neutrophil chemoattractant produced by the rat kidney epithelioid cell line NRK 52E is a protein related to the KC/gro protein J. Biol. Chem. 264 1989 19559 19563
47. K. Watanabe, M. Suematsu, M. Iida, K. Takaishi, Y. Iizuka, H. Suzuki, M. Suzuki, M. Tsuchiya, and S. Tsurufuji Effect of rat CINC/gro, a member of the interleukin-8 family, on leukocytes in microcirculation of the rat mesentery Exp. Mol. Pathol. 56 1992 60 69