Polycystic ovarian disease: The adrenal connection

Pediatric Endocrinology Reviews

Volumn 3, Issue SUPPL. 1, 2006, Pages 205-207

  Maroulis, George B ^a   Triantafillidis, Ioannis K ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

Adrenal androgen excess; Adrenal. Adrenal androgens; Dexamethasone suppression; Hirsutism. Hyperandrosenism; Polycystic Ovarian Disease; Polycystic ovaries

Indexed keywords

ANDROSTANOLONE; ANDROSTENEDIONE; CORTICAL ANDROGEN STIMULATING HORMONE; DEXAMETHASONE; HORMONE; PRASTERONE; PRASTERONE SULFATE; PROLACTIN; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; UNCLASSIFIED DRUG;

ADRENAL CORTEX; ADRENAL FUNCTION; ADRENAL TUMOR; ANDROGEN RELEASE; ANDROGEN SYNTHESIS; CONFERENCE PAPER; ENZYME DEFECT; FEMALE; HUMAN; HYPERANDROGENISM; HYPERPROLACTINEMIA; OBESITY; OVARY INSUFFICIENCY; OVARY POLYCYSTIC DISEASE; STRESS;

ADRENAL GLANDS; ANDROSTENEDIONE; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; DEXAMETHASONE; DIHYDROTESTOSTERONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYPERANDROGENISM; POLYCYSTIC OVARY SYNDROME; TESTOSTERONE;

EID: 33645414109     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (18)

1. Carmina E, Rosato F, Janni A. Increase DHEAs levels in PCO syndrome: evidence for existence of two subgroups of patients. J Endocrinology Invest 1986;9:5-9
2. Moltz L, Swartz U, Sorensen R, Pickartz H, Hammerstein J. Ovarian and adrenal vein steroids in patients with nonneoplastic hyperandrogenism: selective catheterization findings. Fertil Steril 1984;42:69-75
3. Cunningham SK, Loughlin T, Bertagna X, Girard F, McKenna TJ. Plasma pro-opiomelanocortin fragments and adrenal steroids following administration of metyrapone to normal and hirsute women. J Endocrinol Invest 1988;11:247-253
4. Parker LN, Odell WD. Control of adrenal androgen secretion. Endocr Rev 1980;1:392-410
5. Lobo RA, Granger LR, Paul WL, Goebelsmman U, Mishell DR Jr. Psychological stress and increases in urinary norepinephrine metabolites, platelet, serotonin, and adrenal androgens in women with polycystic ovary syndrome. Am J Obstet Gynecol 1983;145:496-503
6. Lobo RA, Kletzky OA, Kaptein EM, Goebelsmman U. Prolactin modulation of dehydroepiandrosterone sulfate secretion. Am J Obstet Gynecol 1980;138:632-636
7. Moran C, Reyna R, Boots L, Azziz R. Adrenocortical hyperresponsiveness to corticotropine in polycystic ovary syndrome patients with adrenal androgen excess. Fertil Steril 2004;81:126-131
8. Carmina E, Gonzales F, Vidali A, Stancyzk FZ, Ferin M, Lobo RA. The contribution of oestrogen and growth factors to increased adrenal androgen secretion in polycystic ovary syndrome. Hum Reprod 1999;14(2):307-311
9. Lobo RA, Goebelsmman U. Evidence for reduce 3β-o1-hydroxysteroid dehydrogenase activity in some hirsute women thought to have polycystic ovary syndrome. J Clin Endocrinol Metab 1981;53:304-400
10. Maroulis GB, Manlimos F, Garza R, Abraham GE. Serum cortisol and deoxycortisol levels in hirsute premenopausal women. Obstet Gynecol 1976;48:388-391
11. Azziz R, Zaur HA. 21-Hydroxylase deficiency in female hyperandrogenemia: screening and diagnosis. J Clin Endocrinol Metab 1989;69:577-584
12. Komidr S, Kurtz BR, Stevens MD, Karas JG, Biddle JB, Stivens GR. Relative sensitivity and responsivity of serum cortisol and adrenal androgens to α-adrenocorticotropin (1-24) in normal and obese, nonhirsute, eumenorrheic women. J Clin Endocrinol Metab 1986;63:860-864
13. Ruuianinen K, Erkkola R, Gronroos NA, Kaihola HL. Androgen parameters in hirsute women: correlations with body mass index and age. Fertil Steril 1988;50:255-259
14. Silfen ME, Denburg MR, Manibo AM, Lobo AR, Jaffe R, Ferrine M, Levine LS, Oberfield SE. Endocrine, metabolic and sonographic characteristics of PCOS: comparison between nonobese and obese adolescents. J Clin Endocrinol Metab 2003;88:4682-4688
15. Maroulis GB, Abraham GE. Concentrations of androgens in the adrenal zones. In: Adrenal Androgens Edited by A. Genazzani, J.H.H. Thijssen, P. Sliteri. Raven Press, 1980;49-53
16. Gonzales F, Chang L, Horab T, Stanczyk FZ, Crickard K, Lobo RA. Adrenal dynamic responses to physiologic and pharmacologic ACTH stimulation before and after ovarian steroid secretion suppression in PCOS. Fertil Steril 1999;71:439-444
17. Azziz R, Ehramann DA, Legro RS, Fereshetian AG, O'Keefe M, Ghazzi MN. Troglitazone decreases adrenal androgens levels in women with polycystic ovary syndrome. Fertil Steril 2003;79:932-937
18. Abraham GE, Maroulis GB, Boyers SP, Buster JE, Magyar CW. Dexamethasone suppression test in the management of androgenized patients. Obstet Gynecol 1981;57:158-165