No significant association of the 5′ end of neuregulin 1 and schizophrenia in a large Danish sample

Schizophrenia Research

Volumn 83, Issue 1, 2006, Pages 1-5

  Ingason, Andrés ^a   Søeby, Karen ^a   Timm, Sally ^b   Wang, August G ^c   Jakobsen, Klaus D ^d   Fink Jensen, Anders ^e   Hemmingsen, Ralf ^f,g   Berg Rasmussen, Henrik ^a   Werge, Thomas ^a  

^a Mental Health Services CPH   (Denmark)

^b FREDERIKSBERG HOSPITAL   (Denmark)

^c AMAGER HOSPITAL   (Denmark)

^d HVIDOVRE HOSPITAL   (Denmark)

^e Rigshospitalet   (Denmark)

^f BISPEBJERG HOSPITAL   (Denmark)

^g UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Ethnicity; Glutamate; Haplotype; Human; Neurodevelopment; Plasticity

Indexed keywords

NEU DIFFERENTIATION FACTOR;

ARTICLE; CAUCASIAN; CHINESE; CONTROLLED STUDY; DENMARK; DISEASE ASSOCIATION; GENE STRUCTURE; GENETIC ANALYSIS; HAPLOTYPE; HUMAN; ICELAND; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA;

CASE-CONTROL STUDIES; DENMARK; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA;

EID: 33645405342     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2005.12.850     Document Type: Article

References (27)

1. E.S. Anton, M.A. Marchionni, K.F. Lee, and P. Rakic Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex Development 124 18 1997 3501 3510
2. G. Corfas, K. Roy, and J.D. Buxbaum Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia Nat. Neurosci. 7 6 2004 575 580
3. J. Duan, M. Martinez, A.R. Sanders, C. Hou, A.J. Krasner, and D.B. Schwartz Neuregulin 1 (NRG1) and schizophrenia: analysis of a US family sample and the evidence in the balance Psychol. Med. 35 11 2005 1599 1610
4. R.A. Garcia, K. Vasudevan, and A. Buonanno The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses Proc. Natl. Acad Sci. U. S. A. 97 7 2000 3596 3601
5. M. Gardner, A. Gonzalez-Neira, O. Lao, F. Calafell, J. Bertranpetit, and D. Comas Extreme population differences across neuregulin 1 gene, with implications for association studies Mol. Psychiatry 11 1 2005 66 75
6. S. Gretarsdottir, G. Thorleifsson, S.T. Reynisdottir, A. Manolescu, S. Jonsdottir, and T. Jonsdottir The gene encoding phosphodiesterase 4D confers risk of ischemic stroke Nat. Genet. 35 2 2003 131 138
7. D. Hall, J.A. Gogos, and M. Karayiorgou The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations Genes Brain Behav. 3 4 2004 240 248
8. R. Hashimoto, R.E. Straub, C.S. Weickert, T.M. Hyde, J.E. Kleinman, and D.R. Weinberger Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia Mol. Psychiatry 9 3 2004 299 307
9. N. Iwata, T. Suzuki, M. Ikeda, T. Kitajima, Y. Yamanouchi, and T. Inada No association with the neuregulin 1 haplotype to Japanese schizophrenia Mol. Psychiatry 9 2 2004 126 127
10. K.F. Jakobsen, J.N., T. Hansen, L.B. Jansson, J. Parnas, and T. Werge Reliability of clinical ICD-10 schizophrenia diagnoses Nord. J. Psychiatry 59 3 2005 209 212
11. T. Li, H. Stefansson, E. Gudfinnsson, G. Cai, X. Liu, and R.M. Murray Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic/Scottish risk haplotype Mol. Psychiatry 9 7 2004 698 704
12. J. Marchini, P. Donnelly, and L.R. Cardon Genome-wide strategies for detecting multiple loci that influence complex diseases Nat. Genet. 37 4 2005 413 417
13. M. Okada, and G. Corfas Neuregulin 1 downregulates postsynaptic GABAA receptors at the hippocampal inhibitory synapse Hippocampus 14 3 2004 337 344
14. M. Ozaki, M. Sasner, R. Yano, H.S. Lu, and A. Buonanno Neuregulin-beta induces expression of an NMDA-receptor subunit Nature 390 6661 1997 691 694
15. Petryshen, T.L., Middleton, F.A., Kirby, A., Aldinger, K.A., Purcell, S., Tahl, A.R., et al., 2005. Support for involvement of neuregulin 1 in schizophrenia pathophysiology. Mol Psychiatry 10 (4): 366-374, 328.
16. H.I. Rieff, L.T. Raetzman, D.W. Sapp, H.H. Yeh, R.E. Siegel, and G. Corfas Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells J. Neurosci. 19 24 1999 10757 10766
17. C. Rio, H.I. Rieff, P. Qi, T.S. Khurana, and G. Corfas Neuregulin and erbB receptors play a critical role in neuronal migration Neuron 19 1 1997 39 50
18. H. Stefansson, E. Sigurdsson, V. Steinthorsdottir, S. Bjornsdottir, T. Sigmundsson, and S. Ghosh Neuregulin 1 and susceptibility to schizophrenia Am. J. Hum. Genet. 71 4 2002 877 892
19. H. Stefansson, J. Sarginson, A. Kong, P. Yates, V. Steinthorsdottir, and E. Gudfinnsson Association of neuregulin 1 with schizophrenia confirmed in a Scottish population Am. J. Hum. Genet. 72 1 2003 83 87
20. H. Stefansson, V. Steinthorsdottir, T.E. Thorgeirsson, J.R. Gulcher, and K. Stefansson Neuregulin 1 and schizophrenia Ann. Med. 36 1 2004 62 71
21. V. Steinthorsdottir, H. Stefansson, S. Ghosh, B. Birgisdottir, S. Bjornsdottir, and A.C. Fasquel Multiple novel transcription initiation sites for NRG1 Gene 342 1 2004 97 105
22. J.X. Tang, W.Y. Chen, G. He, J. Zhou, N.F. Gu, and G.Y. Feng Polymorphisms within 5′ end of the neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population Mol. Psychiatry 9 1 2004 11 12
23. D.L. Thiselton, B.T. Webb, B.M. Neale, R.C. Ribble, F.A. O'Neill, and D. Walsh No evidence for linkage or association of neuregulin-1 (NRG1) with disease in the Irish study of high-density schizophrenia families (ISHDSF) Mol. Psychiatry 9 8 2004 777 783 (image 729)
24. S. Tosato, P. Dazzan, and D. Collier Association between the neuregulin 1 gene and schizophrenia: a systematic review Schizophr. Bull. 31 3 2005 613 617
25. N.M. Williams, A. Preece, G. Spurlock, N. Norton, H.J. Williams, and S. Zammit Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia Mol. Psychiatry 8 5 2003 485 487
26. J.Z. Yang, T.M. Si, Y. Ruan, Y.S. Ling, Y.H. Han, and X.L. Wang Association study of neuregulin 1 gene with schizophrenia Mol. Psychiatry 8 7 2003 706 709
27. X. Zhao, Y. Shi, J. Tang, R. Tang, L. Yu, and N. Gu A case control and family based association study of the neuregulin 1 gene and schizophrenia J. Med. Genet. 41 1 2004 31 34