메뉴 건너뛰기




Volumn 290, Issue 3, 2006, Pages

Vascular Na+/Ca2+ exchanger: Implications for the pathogenesis and therapy of salt-dependent hypertension

Author keywords

Hypertension; Na+ K+ ATPase; Salt intake; Vascular smooth muscle

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 2 [4 (2,5 DIFLUOROBENZYLOXY)PHENOXY] 5 ETHOXYANILINE; HUMORAL ANTIBODY; OUABAIN; PROTEIN INHIBITOR; SN 6; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG; YM 244769; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIHYPERTENSIVE AGENT;

EID: 33645405103     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00592.2005     Document Type: Review
Times cited : (28)

References (100)
  • 3
    • 0025990187 scopus 로고
    • Pathogenesis of essential hypertension. A link between dietary salt and high blood pressure
    • Blaustein MP and Hamlyn JM. Pathogenesis of essential hypertension. A link between dietary salt and high blood pressure. Hypertension 18: III184-III195, 1991.
    • (1991) Hypertension , vol.18
    • Blaustein, M.P.1    Hamlyn, J.M.2
  • 4
    • 0032801648 scopus 로고    scopus 로고
    • Sodium/calcium exchange: Its physiological implications
    • Blaustein MP and Lederer WJ. Sodium/calcium exchange: its physiological implications. Physiol Rev 79: 763-854, 1999.
    • (1999) Physiol Rev , vol.79 , pp. 763-854
    • Blaustein, M.P.1    Lederer, W.J.2
  • 7
    • 0021941839 scopus 로고
    • Na-Ca exchange in vascular smooth muscle
    • Brading AF and Lategan TW. Na-Ca exchange in vascular smooth muscle. J Hypertens 3: 109-116, 1985.
    • (1985) J Hypertens , vol.3 , pp. 109-116
    • Brading, A.F.1    Lategan, T.W.2
  • 8
    • 4143126539 scopus 로고    scopus 로고
    • Calcium-dependent regulation of calcium efflux by the cardiac sodium/calcium exchanger
    • Chernysh O, Condrescu M, and Reeves JP. Calcium-dependent regulation of calcium efflux by the cardiac sodium/calcium exchanger. Am J Physiol Cell Physiol 287: C797-C806, 2004.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Chernysh, O.1    Condrescu, M.2    Reeves, J.P.3
  • 9
    • 0002563645 scopus 로고
    • Hemodynamic and hypotensive effects of long-term therapy with chlorothiazide
    • Conway J and Lauwers P. Hemodynamic and hypotensive effects of long-term therapy with chlorothiazide. Circulation 21: 21-27, 1960.
    • (1960) Circulation , vol.21 , pp. 21-27
    • Conway, J.1    Lauwers, P.2
  • 11
    • 0015951071 scopus 로고
    • Genetic influence of the kidneys on blood pressure. Evidence from chronic renal homografts in rats with opposite predispositions to hypertension
    • Dahl LK, Heine M, and Thompson K. Genetic influence of the kidneys on blood pressure. Evidence from chronic renal homografts in rats with opposite predispositions to hypertension. Circ Res 40: 94-101, 1974.
    • (1974) Circ Res , vol.40 , pp. 94-101
    • Dahl, L.K.1    Heine, M.2    Thompson, K.3
  • 13
    • 0018356530 scopus 로고
    • Sodium and calcium interactions in vascular smooth muscle cells of the rabbit ear artery
    • Droogmans G and Casteels R. Sodium and calcium interactions in vascular smooth muscle cells of the rabbit ear artery. J Gen Physiol 74: 57-70, 1979.
    • (1979) J Gen Physiol , vol.74 , pp. 57-70
    • Droogmans, G.1    Casteels, R.2
  • 15
    • 0029873197 scopus 로고    scopus 로고
    • Intersalt revisited: Further analyses of 24-hour sodium excretion and blood pressure within and across populations
    • Intersalt Cooperative Research Group
    • Elliott P, Stamler J, Nichols R, Dyer AR, Stamler R, Kesteloot H, and Marmot M. Intersalt revisited: further analyses of 24-hour sodium excretion and blood pressure within and across populations. Intersalt Cooperative Research Group. Br Med J 312: 1249-1253, 1996.
    • (1996) Br Med J , vol.312 , pp. 1249-1253
    • Elliott, P.1    Stamler, J.2    Nichols, R.3    Dyer, A.R.4    Stamler, R.5    Kesteloot, H.6    Marmot, M.7
  • 16
    • 0034642345 scopus 로고    scopus 로고
    • Endogenous Na,K pump ligands are differentially regulated during acute NaCl loading of Dahl rats
    • Fedorova OV, Lakatta EG, and Bagrov AY. Endogenous Na,K pump ligands are differentially regulated during acute NaCl loading of Dahl rats. Circulation 102: 3009-3014, 2000.
    • (2000) Circulation , vol.102 , pp. 3009-3014
    • Fedorova, O.V.1    Lakatta, E.G.2    Bagrov, A.Y.3
  • 19
  • 20
    • 0033797089 scopus 로고    scopus 로고
    • Putative roles of ouabainlike compound in hypertension: Revisited
    • Goto A and Yamada K. Putative roles of ouabainlike compound in hypertension: revisited. Hypertens Res 23: S7-S13, 2000.
    • (2000) Hypertens Res , vol.23
    • Goto, A.1    Yamada, K.2
  • 21
    • 0025817650 scopus 로고
    • Blood pressure control: Special role of the kidneys and body fluid
    • Guyton AC. Blood pressure control: special role of the kidneys and body fluid. Science 252: 1813-1816, 1991.
    • (1991) Science , vol.252 , pp. 1813-1816
    • Guyton, A.C.1
  • 22
    • 0023682659 scopus 로고
    • Ionic control of vascular smooth muscle cells
    • Haddy FJ. Ionic control of vascular smooth muscle cells. Kidney Int 346: S2-S8, 1988.
    • (1988) Kidney Int , vol.346
    • Haddy, F.J.1
  • 23
    • 0029133518 scopus 로고
    • Role of dietary salt in hypertension
    • Haddy FJ and Pamnani MB. Role of dietary salt in hypertension. J Am Coll Nutr 14: 428-438, 1995.
    • (1995) J Am Coll Nutr , vol.14 , pp. 428-438
    • Haddy, F.J.1    Pamnani, M.B.2
  • 25
    • 0029880847 scopus 로고    scopus 로고
    • Endogenous ouabain, sodium balance and blood pressure: A review and a hypothesis
    • Hamlyn JM, Hamilton BP, and Manunta P. Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis. J Hypertens 14: 151-167, 1996.
    • (1996) J Hypertens , vol.14 , pp. 151-167
    • Hamlyn, J.M.1    Hamilton, B.P.2    Manunta, P.3
  • 31
    • 3042579803 scopus 로고    scopus 로고
    • 2+ exchange by SN-6 [2-[4-(4-nitrobenzyloxy)benzyl] thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative
    • 2+ exchange by SN-6 [2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4- carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative. Mol Pharmacol 66: 45-55, 2004.
    • (2004) Mol Pharmacol , vol.66 , pp. 45-55
    • Iwamoto, T.1    Inoue, Y.2    Ito Sakaue, T.K.3    Kita, S.4    Katsuragi, T.5
  • 37
    • 0031816393 scopus 로고    scopus 로고
    • 2+ exchanger isoforms by divalent cations and isothiourea derivative
    • 2+ exchanger isoforms by divalent cations and isothiourea derivative. Am J Physiol Cell Physiol 275: C423-C430, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.275
    • Iwamoto, T.1    Shigekawa, M.2
  • 43
    • 0031442209 scopus 로고    scopus 로고
    • + pump alpha subunit isoforms in plasmalemma. Physiological implications
    • + pump alpha subunit isoforms in plasmalemma. Physiological implications. Ann NY Acad Sci 834: 524-536, 1997.
    • (1997) Ann NY Acad Sci , vol.834 , pp. 524-536
    • Juhaszova, M.1    Blaustein, M.P.2
  • 44
    • 0003215511 scopus 로고
    • Development and use of inhibitors to study sodium-calcium exchange
    • edited by Allen TJ, Noble D, and Reuter H. Oxford, UK: Oxford Science Publications
    • Kaczorowsky GJ, Garcia ML, King VF, and Slaughter RS. Development and use of inhibitors to study sodium-calcium exchange. In: Sodium-Calcium Exchange, edited by Allen TJ, Noble D, and Reuter H. Oxford, UK: Oxford Science Publications, 1989, p. 66-101.
    • (1989) Sodium-Calcium Exchange , pp. 66-101
    • Kaczorowsky, G.J.1    Garcia, M.L.2    King, V.F.3    Slaughter, R.S.4
  • 48
    • 0033596973 scopus 로고    scopus 로고
    • Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings
    • Krushkal J, Ferrell R, Mockrin SC, Turner ST, Sing CF, and Boerwinkle E. Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation 99: 1407-1410, 1999.
    • (1999) Circulation , vol.99 , pp. 1407-1410
    • Krushkal, J.1    Ferrell, R.2    Mockrin, S.C.3    Turner, S.T.4    Sing, C.F.5    Boerwinkle, E.6
  • 49
    • 11844251148 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: Effects on heart failure
    • Kuramochi T, Kakefuda A, Yamada H, Ogiyama T, Taguchi T, and Sakamoto S. Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure. Bioorg Med Chem 13: 725-734, 2005.
    • (2005) Bioorg Med Chem , vol.13 , pp. 725-734
    • Kuramochi, T.1    Kakefuda, A.2    Yamada, H.3    Ogiyama, T.4    Taguchi, T.5    Sakamoto, S.6
  • 52
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton RP, Gharavi AG, and Geller DS. Molecular mechanisms of human hypertension. Cell 104: 545-556, 2001.
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 55
    • 0028271160 scopus 로고
    • Ouabain-induced hypertension in the rat: Relationships among plasma and tissue ouabain and blood pressure
    • Manunta P, Rogowski AC, Hamilton BP, and Hamlyn JM. Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure. J Hypertens 12: 549-560, 1994.
    • (1994) J Hypertens , vol.12 , pp. 549-560
    • Manunta, P.1    Rogowski, A.C.2    Hamilton, B.P.3    Hamlyn, J.M.4
  • 57
    • 0022896307 scopus 로고
    • Sodium-calcium exchange exists across the cell membrane of intact vascular smooth muscle cells
    • Matlib MA, Whitmer KR, MacCarthy EP, and Ooi BS. Sodium-calcium exchange exists across the cell membrane of intact vascular smooth muscle cells. J Hypertens 4: S222-S223, 1986.
    • (1986) J Hypertens , vol.4
    • Matlib, M.A.1    Whitmer, K.R.2    MacCarthy, E.P.3    Ooi, B.S.4
  • 61
    • 15544364940 scopus 로고    scopus 로고
    • Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases
    • Meneton P, Jeunemaitre X, De Wardener HE, and MacGregor GA. Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol Rev 85: 679-715, 2005.
    • (2005) Physiol Rev , vol.85 , pp. 679-715
    • Meneton, P.1    Jeunemaitre, X.2    De Wardener, H.E.3    MacGregor, G.A.4
  • 63
    • 0025248725 scopus 로고
    • Effects of interstrain renal transplantation on NaCl-induced hypertension in Dahl rats
    • Morgan DA, DiBona GF, and Mark AL. Effects of interstrain renal transplantation on NaCl-induced hypertension in Dahl rats. Hypertension 15: 436-442, 1990.
    • (1990) Hypertension , vol.15 , pp. 436-442
    • Morgan, D.A.1    DiBona, G.F.2    Mark, A.L.3
  • 64
    • 0021259699 scopus 로고
    • Intracellular sodium, membrane potential, and contractility of rat mesenteric small arteries
    • Mulvany MJ, Aalkjaer C, and Petersen TT. Intracellular sodium, membrane potential, and contractility of rat mesenteric small arteries. Circ Res 54: 740-749, 1984.
    • (1984) Circ Res , vol.54 , pp. 740-749
    • Mulvany, M.J.1    Aalkjaer, C.2    Petersen, T.T.3
  • 69
    • 0018579961 scopus 로고
    • Na-Ca exchange and tension development in guinea-pig aorta
    • Ozaki H and Urakawa N. Na-Ca exchange and tension development in guinea-pig aorta. Naunyn Schmiedebergs Arch Pharmacol 309: 171-178, 1979.
    • (1979) Naunyn Schmiedebergs Arch Pharmacol , vol.309 , pp. 171-178
    • Ozaki, H.1    Urakawa, N.2
  • 71
    • 84939690752 scopus 로고
    • Effect of sodium gradient on the rate of relaxation of rat mesenteric small arteries from potassium contractures
    • Petersen TT and Mulvaney MJ. Effect of sodium gradient on the rate of relaxation of rat mesenteric small arteries from potassium contractures. Blood Vessels 21: 279-289, 1984.
    • (1984) Blood Vessels , vol.21 , pp. 279-289
    • Petersen, T.T.1    Mulvaney, M.J.2
  • 72
    • 0033846740 scopus 로고    scopus 로고
    • 2+ exchange inhibitor KB-R7943 also blocks native and expressed neuronal nicotinic receptors
    • 2+ exchange inhibitor KB-R7943 also blocks native and expressed neuronal nicotinic receptors. Br J Pharmacol 130: 1893-1902, 2000.
    • (2000) Br J Pharmacol , vol.130 , pp. 1893-1902
    • Pintado, A.J.1    Herrero, C.J.2    Garcia, A.G.3    Montiel, C.4
  • 73
    • 0032127132 scopus 로고    scopus 로고
    • Lessons from rat models of hypertension: From Goldblatt to genetic engineering
    • Pinto YM, Paul M, and Ganten D. Lessons from rat models of hypertension: from Goldblatt to genetic engineering. Cardiovasc Res 39: 77-88, 1998.
    • (1998) Cardiovasc Res , vol.39 , pp. 77-88
    • Pinto, Y.M.1    Paul, M.2    Ganten, D.3
  • 78
    • 0024788875 scopus 로고
    • Sodium-calcium exchange: A possible target for drug development
    • Reeves JP. Sodium-calcium exchange: a possible target for drug development. Drug Dev Res 18: 295-304, 1989.
    • (1989) Drug Dev Res , vol.18 , pp. 295-304
    • Reeves, J.P.1
  • 84
    • 0036106788 scopus 로고    scopus 로고
    • Endogenous cardiac glycosides, a new class of steroid hormones
    • Schoner W. Endogenous cardiac glycosides, a new class of steroid hormones. Eur J Biochem 269: 2440-2448, 2002.
    • (2002) Eur J Biochem , vol.269 , pp. 2440-2448
    • Schoner, W.1
  • 85
    • 0042206722 scopus 로고    scopus 로고
    • Sodium/calcium exchanger (NCX1) macromolecular complex
    • Schulze DH, Muqhal M, Lederer WJ, and Ruknudin AM. Sodium/calcium exchanger (NCX1) macromolecular complex. J Biol Chem 278: 28849-28855, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 28849-28855
    • Schulze, D.H.1    Muqhal, M.2    Lederer, W.J.3    Ruknudin, A.M.4
  • 86
    • 0035843910 scopus 로고    scopus 로고
    • 2+ exchange: Molecular and pharmacological aspects
    • 2+ exchange: molecular and pharmacological aspects. Circ Res 88: 864-876, 2001.
    • (2001) Circ Res , vol.88 , pp. 864-876
    • Shigekawa, M.1    Iwamoto, T.2
  • 87
    • 0031824939 scopus 로고    scopus 로고
    • 2+ exchanger knockdown by antisense oligodeoxynucleotides in arterial myocytes
    • 2+ exchanger knockdown by antisense oligodeoxynucleotides in arterial myocytes. Am J Physiol Cell Physiol 275: C251-C259, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.275
    • Slodzinski, M.K.1    Blaustein, M.P.2
  • 89
    • 0023665410 scopus 로고
    • 2+ produced by angiotensin II in cultured arterial muscle cells
    • 2+ produced by angiotensin II in cultured arterial muscle cells. J Biol Chem 262: 17455-17460, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 17455-17460
    • Smith, J.B.1    Smith, L.2
  • 91
    • 0033794864 scopus 로고    scopus 로고
    • Endogenous digitalislike factor: An update
    • Takahashi H. Endogenous digitalislike factor: an update. Hypertens Res 23: S1-S5, 2000.
    • (2000) Hypertens Res , vol.23
    • Takahashi, H.1
  • 93
    • 0036193794 scopus 로고    scopus 로고
    • Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents
    • Tanaka H, Nishimaru K, Aikawa T, Hirayama W, Tanaka Y, and Shigenobu K. Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents. Br J Pharmacol 135: 1096-1100, 2002.
    • (2002) Br J Pharmacol , vol.135 , pp. 1096-1100
    • Tanaka, H.1    Nishimaru, K.2    Aikawa, T.3    Hirayama, W.4    Tanaka, Y.5    Shigenobu, K.6
  • 94
    • 33646475077 scopus 로고
    • Salt and hypertension
    • Tobian L. Salt and hypertension. Hypertension 17 Suppl: 51-58, 1992.
    • (1992) Hypertension , vol.17 , Issue.SUPPL. , pp. 51-58
    • Tobian, L.1
  • 95
    • 0018858520 scopus 로고
    • Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders
    • Van Brummelen P, Man in't Veld AJ, and Schalekamp MA. Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders. Clin Pharmacol Ther 27: 328-336, 1980.
    • (1980) Clin Pharmacol Ther , vol.27 , pp. 328-336
    • Van Brummelen, P.1    Man In't Veld, A.J.2    Schalekamp, M.A.3
  • 98
    • 0035005037 scopus 로고    scopus 로고
    • Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes
    • Weber CR, Ginsburg KS, Philipson KD, Shannon TR, and Bers DM. Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes. J Gen Physiol 117: 119-131, 2001.
    • (2001) J Gen Physiol , vol.117 , pp. 119-131
    • Weber, C.R.1    Ginsburg, K.S.2    Philipson, K.D.3    Shannon, T.R.4    Bers, D.M.5
  • 99
    • 0029928474 scopus 로고    scopus 로고
    • Salt sensitivity of blood pressure in humans
    • Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension 27: 481-490, 1996.
    • (1996) Hypertension , vol.27 , pp. 481-490
    • Weinberger, M.H.1
  • 100
    • 0025650629 scopus 로고
    • International cooperative study on the relationship between dietary factors and blood pressure: A report from the Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study
    • Yamori Y, Nara Y, Mizushima S, Mano M, Sawamura M, Kihara M, and Horie R. International cooperative study on the relationship between dietary factors and blood pressure: a report from the Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study. J Cardiovasc Pharmacol 16: S43-S47, 1990.
    • (1990) J Cardiovasc Pharmacol , vol.16
    • Yamori, Y.1    Nara, Y.2    Mizushima, S.3    Mano, M.4    Sawamura, M.5    Kihara, M.6    Horie, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.