Permanent renal parenchymal defects after febrile UTI are closely associated with vesicoureteric reflux

Pediatric Nephrology

Volumn 21, Issue 4, 2006, Pages 521-526

  Polito, Cesare ^a,b   Rambaldi, Pier Francesco ^a   Signoriello, Giuseppe ^a   Mansi, Luigi ^a   La Manna, Angela ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Clinica Pediatrica   (Italy)

Author keywords

DMSA scintigraphy; Isotopic cystography; Renal defects; Urinary infection; Vesicoureteric reflux

Indexed keywords

SUCCIMER TC 99M;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; CYSTOGRAPHY; DISEASE ASSOCIATION; FEMALE; FEVER; HUMAN; INFANT; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY PARENCHYMA; KIDNEY SCINTISCANNING; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIOACTIVITY; URINARY TRACT INFECTION; VESICOURETERAL REFLUX;

FEMALE; FEVER; HUMANS; INFANT; KIDNEY DISEASES; MALE; PROSPECTIVE STUDIES; URINARY TRACT INFECTIONS; VESICO-URETERAL REFLUX;

EID: 33645371536     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-006-0036-3     Document Type: Article

References (32)

1. Lin DS, Huang SH, Lin CC, Tung YC, Huang TT, Chiu NC, Koa HA, Hung HY, Hsu CH, Hsieh WS, Yang DI, Huang FY (2000) Urinary tract infection in febrile infants younger than eight weeks of age. Pediatrics 105:E20
2. Jacobson SH, Hansson S, Jakobsson B (1999) Vesicoureteric reflux: occurrence and long-term risks. Acta Paediatr Suppl 43:22-30
3. Patzer L, Seeman T, Luck C, Wuhl E, Janda J, Misselwitz J (2003) Day-and night-time blood pressure elevation in children with higher grades of renal scarring. J Pediatr 142:117-122
4. McGladdery SJ, Aparicio S, Verrier-Jones K, Roberts R, Sacks SH (1992) Outcome of pregnancy in an Oxford-Cardiff cohort of women with previous bacteriuria. Q J Med 83:533-539
5. Goldraich NP, Ramos AL, Goldraich IH (1989) Urography versus DMSA scan in children with vesicoureteric reflux. Pediatr Nephrol 3:1-5
6. Jakobsson B, Svensson L (1997) Transient pyelonephritic changes on 99mTechnetium-dimercaptosuccinic acid scan for at least 5 months after infection. Acta Paediatr 86:803-807
7. Gordon I, Barkovics M, Pindoria S, Cole TJ, Woolf AS (2003) Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: A systematic review and meta-analysis. J Am Soc Nephrol 14:739-744
8. Paltiel HJ, Rupic RC, Kiruluta HG (1992) Enhanced detection of vesicoureteral reflux in infants and children with use of cyclic voiding cystourethrography. Radiology 184:753-755
9. Polito C, Moggio G, La Manna A, Cioce F, Cappabianca S, Di Toro R (2000) Cyclic voiding cystourethrography in the diagnosis of occult vesicoureteric reflux in infants and children. Pediatr Nephrol 14:39-41
10. Polito C, Rambaldi PF, La Manna A, Mansi PL, Di Toro R (2000) Enhanced detection of vesicoureteric reflux with isotopic cystography. Pediatr Nephrol 14:827-830
11. Nasrallah PF, Nara S, Crawford J (1982) Clinical applications of nuclear cystography. J Urol 128:550-553
12. Fretzaias A, Karpathios T, Dimitriou P, Nicolaidou P, Matsaniotis N (1984) Grading of vesicoureteral reflux by radionuclide cystography. Pediatr Radiol 14:148-150
13. Kogan SJ, Sigler L, Levitt SB, Reda EF, Weiss R, Greifer I (1986) Elusive vesicoureteral reflux in children with normal contrast cystograms. J Urol 136:325-328
14. Saraga M, Stanicic A, Markovic V (1996) The role of direct radionuclide cystography in evaluation of vesicoureteral reflux. Scand J Urol Nephrol 30:367-371
15. Poli-Merol ML, Francois S, Pfliger F, Lefebvre F, Roussel B, Liehn JC, Daoud S (1998) Interest of direct radionuclide cystography in repeated urinary tract infection exploration in childhood. Eur J Pediatr Surg 8:339-342
16. Schwartz GJ, Brion LP, Spitzer A (1987) The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children and adolescents. Pediatr Clin North Am 34:571-590
17. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents (1996) Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: A working group report from the National High Blood Pressure Education Program. Pediatrics 98:649-658
18. Brendstrup L, Carlsen N, Nielsen SL, Dyrbye M, Eiken M, Krasilnikoff PA, Gertz TC (1983) Micturition cystourethrography using X-ray or scintigraphy in children with reflux. Acta Paediatr Scand 72:559-562
19. Dikshit MP, Acharya VN, Shikare S, Merchant S, Pardanani DS (1993) Comparison of direct radionuclide cystography with micturating cystourethrography for the diagnosis of vesicoureteric reflux and its correlation with cystoscopic appearances of the ureteric orifices. Nephrol Dial Transplant 8:600-602
20. Zechmann W, Raushmeier H, Dumfahrt H, Fill H, Joost J, Riccabona G (1983) Value and indication for isotope reflux cystography in children. Acta Medica Austriaca 10:57-60
21. Zhang G, Day DL, Loken M, Gonzalez R (1987) Grading of reflux by radionuclide cystography. Clin Nucl Med 12:106-109
22. Tamminen-Mobius T, Brunier E, Ebel KD, Lebowitz R, Olbing H, Seppanen U, Sixt R (1992) Cessation of vesicoureteral reflux for 5 years in infants and children allocated to medical treatment. The International Reflux Study in Children. J Urol 148:1662-1666
23. Anderson NG, Abbott GD, Mogridge N, Allen RB, Maling TM, Wells JE (1997) Vesicoureteric reflux in the newborn: Relationship to fetal pelvic diameter. Pediatr Nephrol 11:610-616
24. Phan V, Traubici J, Hershenfield B, Stephens D, Rosenblum ND, Geary DF (2004) Vesicoureteral reflux in infants with isolated antenatal hydronephrosis. Pediatr Nephrol 19:819-820
25. Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER (2003) Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 348:195-202
26. Goldman M, Bistritzer T, Horne T, Zoareft I, Aladjem M (2000) The etiology of renal scars in infants with pyelonephritis and vesicoureteral reflux. Pediatr Nephrol 14:385-388
27. Olbing H, Smellie JM, Jodal U, Lax H (2003) New renal scars in children with severe VUR: A 10-year study of randomised treatment. Pediatr Nephrol 18:1128-1131
28. Wennerstrom M, Hansson S, Jodal U, Stokland E (2000) Primary and acquired renal scarring in boys and girls with urinary tract infection. J Pediatr 136:30-34
29. Ardissino G, Dacco V, Testa S, Bonaudo R, Claris-Appiani A, Taioli E, Marra G, Edefonti A, Sereni F, ItalKid Project (2003) Epidemiology of chronic renal failure in children: Data from the ItalKid project. Pediatrics 111:e382-e387
30. Smellie JM, Barratt TM, Chantler C, Gordon I, Prescod NP, Ransley PG, Woolf AS (2001) Medical versus surgical treatment in children with severe bilateral vesicoureteric reflux and bilateral nephropathy: A randomized trial. Lancet 357:1329-1333
31. Mingin GC, Nguien HT, Baskin LS (2004) Abnormal dimercapto-succinic acid scans predict an increased risk of breakthrough infection in children with vesicoureteral reflux. J Urol 172:1075-1077
32. Rubenstein JN, Maizels M, Kim S, Houston JTB (2003) The PIC cystogram: A novel approach to identify "occult" vesicoureteric reflux in children with febrile urinary tract infections. J Urol 169:2339-2343