Liquid chromatography with electrospray ionization mass spectrometry method for the assay of glucosamine sulfate in human plasma: Validation and application to a pharmacokinetic study

Biomedical Chromatography

Volumn 20, Issue 3, 2006, Pages 251-256

  Huang, Tao Min ^a   Cai, Lei ^a   Yang, Beng ^a   Zhou, Man Xiang ^b   Shen, Yun Fei ^b   Duan, Geng Li ^a  

^a FUDAN UNIVERSITY   (China)

^b Shanxi Kang Bao Biology Stock Ltd Co   (China)

Author keywords

Electrospray ionization; Glucosamine sulfate; Mass spectrometry

Indexed keywords

ACETONITRILE; ASSAYS; BIOCHEMISTRY; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; PLASMA (HUMAN); POSITIVE IONS; SULFUR COMPOUNDS;

CHROMATOGRAPHIC SEPARATIONS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; GLUCOSAMINE SULPHATE; HUMAN PLASMAS; LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION-MASS SPECTROMETRIES; MOBILE PHASIS; PHARMACOKINETIC STUDIES; PLASMA PROTEIN; SUPERNATANTS; VORTEX MIXING;

MASS SPECTROMETRY;

ACETIC ACID; ACETONITRILE; GLUCOSAMINE SULFATE; METHANOL; PHENYL ISOTHIOCYANATE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CENTRIFUGATION; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE REGIMEN; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FEASIBILITY STUDY; FLOW RATE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; PLASMA; PROTEIN BLOOD LEVEL; REPRODUCIBILITY; SEPARATION TECHNIQUE; SUPERNATANT; VALIDATION PROCESS; VOLUNTEER; VORTEX MOTION;

EID: 33645355129     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.558     Document Type: Article

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