Characterization of supersaturated lidocaine/polyacrylate pressure sensitive adhesive systems: Thermal analysis and FT-IR

Journal of Pharmaceutical Sciences

Volumn 95, Issue 3, 2006, Pages 701-713

  Cui, Yong ^a   Frank, Sylvan G ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

DSC; Duro TakR; FT IR; Intermolecular interaction; Lidocaine; Pressure sensitive adhesive; Supersaturation; Thermal analysis; Transdermal drug delivery

Indexed keywords

ADHESIVE AGENT; DT 2287; DURO TAK; LIDOCAINE; POLYACRYLIC ACID; POLYMER; UNCLASSIFIED DRUG;

ADHESION; ARTICLE; CONFORMATION; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG MIXTURE; ENTROPY; GLASS TRANSITION TEMPERATURE; INFRARED SPECTROSCOPY; MISCIBILITY; MOLECULAR INTERACTION; PRESSURE; THERMODYNAMICS;

EID: 33645344621     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20445     Document Type: Review

References (36)

1. Moser K, Kriwet K, Kalia YN, Guy RH. 2001. Enhanced skin permeation of a lipophilic drug using supersaturated formulations. J Control Rel 73:245-253.
2. Hadgraft J. 1999. Passive enhancement strategies in topical and transdermal drug delivery. Int J Pharm 184:1-6.
3. Cui Y, Frank SG. Enhancement of in vitro drug release from supersaturated lidocaine/pressure sensitive adhesive patches: Effect of barrier membranes and hydration (in preparation).
4. Cui Y, Frank SG. 2005. Isothermal crystallization kinetics of lidocaine in supersaturated lidocaine/polyacrylate pressure sensitive adhesive systems: nucleation. J Pharm Sci 94:2039-2048.
5. Cui Y, Frank SG. Avrami kinetics of isothermal crystallization of lidocaine in supersaturated lidocaine/polyacrylate pressure sensitive adhesive systems. J Pharm Sci (submitted).
6. Feldstein MM, Kuptsov SA, Shandryuk GA. 2000. Coherence of thermal transition on poly(N-vinyl pyrrolidone)-poly(ethylene glycol) compatible blends 2. The temperature of maximum cold crystallization rate versus glass transition. Polymer 41:5339-5348.
7. Rostami S. 1990. Crystallization behavior of semicrystalline miscible blends. Polymer 31:899-904.
8. MacKnight WJ, Karasz FE, Fried JR. 1978. In: Paul DR, Newman S, editors. Polymer blends, 1. New York: Academic Press, chap. 5.
9. Cruz CA, Barlow JW, Paul DR. 1980. J Appl Polym Sci 25:1559-1571.
10. Flory PJ. 1953. Principles of polymer chemistry. Ithaca, NY: Cornell University.
11. Fox TG. 1956. Influence of diluent and copolymer composition on the glass transition temperature of polymer system. Bull Am Phys Soc 1:123.
12. Gordon M, Taylor JS. 1952. Ideal copolymers and the second-order transition of synthetic rubbers. I. Non-crystalline copolymers. J Appl Chem 2:493-500.
13. Kwei TK. 1984. The effect of hydrogen bonding on the glass transition temperatures of polymer mixtures. J Polym Sci Polym Lett 22:307-313.
14. Couchman PR. 1978. Compositional variation of glass transition temperature. 1. Application of the thermodynamic theory to compatible polymer blends. Macromolecules 11:1156-1161.
15. Feldstein M.M. 2001. Peculiarities of glass transition temperature relation to the composition of poly(N-vinyl pyrrolidone) blends with short chain poly(ethylene glycol). Polymer 42:7719-7726.
16. Breckner M.J, Schneider H.A, Cantow H.J. 1988. Approach to the composition dependence of glass transition temperature of compatible polymer blends. 2. The effect of local chain orientation. Macromol Chem 189:2085-2097.
17. Couchman P.R, Karasz F.E. 1978. A classical thermodynamic discussion of the effect of composition on glass transition temperatures. Macromolecules 11:117-119.
18. Schneider H.A. 1997. Conformational entropy contributions to the glass temperature of blends of miscible polymers. J Res Natl Inst Stand Technol 102:229-248.
19. Lu X, Weiss R.A. 1992. Relationship between the glass transition temperature and the interaction parameter of miscible binary polymer blends. Macromolecules 25:3242-3246.
20. Slark A.T. 1999. Application of the Kwei equation to the glass transition of dye solute-polymer blends. Polymer 40:1935-1941.
21. Painter P.C, Graf J.F, Coleman M.M. 1991. Effect of hydrogen bonding on the enthalpy of mixing and the composition dependence of glass transition temperature in polymer blends. Macromolecules 24:5630-5638.
22. Schneider H.A. 1989. Glass transition behavior of compatible polymer blends. Polymer 30:771-779.
23. Schneider H.A, Di Marzio E.A. 1992. The glass temperature of polymer blends: Comparison of both the free volume and the entropy predictions with data. Polymer 33:3453-3461.
24. Breckner M.J, Schneider H.A, Cantow H.J. 1988. Approach to the composition dependence of glass transition temperature of compatible polymer blends. Polymer 29:78-85.
25. Villics T, Schneider H.A, Manoviciu V, Manoviciu I. 1997. A new approach to PVC-plasticizer interaction by using a Tg concentration power equation. Polymer 38:1865-1870.
26. Schneider H.A. 1999. The meaning of the glass temperature of random copolymers and miscible polymer blends. J Therm Anal Cal 56:983-989.
27. Schneider H.A. 1989. Glass transition behavior of compatible polymer blends. Polymer XX:771-779.
28. Braun G, Kovacs A.J. 1965. In: Prins J.A, editor. Physics of non-crystalline solids. Amsterdam: North-Holland.
29. Neogi P. 1996. Diffusion in polymers. New York: Marcel Dekker.
30. Feldstein M.M, Shandryuk G.A. 1999. Quantitative relation of glass transition temperature to polymer-plasticizer binding degree. Proceed Int'l Symp Control Rel Bioact Mater 26:381-382.
31. Matsumoto T, Zografi G. 1999. Physical properties of solid molecular dispersions of indomethacin with poly(vinylprrolidone) and Poly(vinylpyrrolidone-co-vinyl-acetate) in relation to indomethacin crystallization. Pharm Res 16:1722-1728.
32. Taylor L.S, Zografi G. 1997. Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions. Pharm Res 14:1691-1698.
33. Slark A.T, Hadgett P.M. 1998. Specific interactions between dye solutes and polymers: The effect of dye solute structure and concentration. Polymer 39:2055-2060.
34. Morimoto Y, Kokubo T, Sugibayashi K. 1992. Diffusion of drugs in acrylic-type pressure-sensitive adhesive matrix. II. Influence of interaction. J Control Rel 18:113-122.
35. Hanson A.W, Banner D.W. 1974. 2-diethylamino-2′,6′- acetoxylidide (Lidocaine). Acta Cryst B30:2486-2487.
36. Private communication with Mrs. Susan Lydzinski of National Starch and Chemical Co