Alloimmune neonatal neutropenia: Can we afford the consequences of a missed diagnosis?

Journal of Paediatrics and Child Health

Volumn 42, Issue 1-2, 2006, Pages 59-61

  Williams, Bronwyn A ^a,c   Fung, Y L ^b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b AUSTRALIAN RED CROSS BLOOD SERVICE   (Australia)

^c Haematology Department   (Australia)

Author keywords

Alloimmune; Incidence; Neonate; Neutropenia

Indexed keywords

GRANULOCYTE ANTIBODY;

ALLOIMMUNE NEWBORN NEUTROPENIA; ALLOIMMUNITY; ARTICLE; DIAGNOSTIC ERROR; FOLLOW UP; HUMAN; INCIDENCE; INFECTION; MAJOR CLINICAL STUDY; NEUTROPENIA; NEWBORN; NEWBORN DISEASE; NEWBORN SCREENING; PRIORITY JOURNAL; SERODIAGNOSIS; UMBILICAL CORD BLOOD;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; DIAGNOSIS, DIFFERENTIAL; HUMANS; INFANT, NEWBORN; NEONATAL SCREENING; NEUTROPENIA; PROSPECTIVE STUDIES; QUEENSLAND;

EID: 33645303505     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/j.1440-1754.2006.00774.x     Document Type: Article

References (18)

1. Bux J Jung KD Kauth T Mueller-Eckhardt C. Serological and clinical aspects of granulocyte antibodies leading to alloimmune neonatal neutropenia. Transfus. Med. 1992 2 2 143 9.
2. Skacel PO Stacey TE Tidmarsh EF Contreras M. Maternal alloimmunization to HLA platelet and granulocyte-specific antigens during pregnancy: Its influence on cord blood granulocyte and platelet counts. Br. J. Haematol. 1989 71 119 23.
3. Clay M Kline W McCullough J. The frequency of granulocyte-specific antibodies in postpartum sera and a family study of the 6B antigen. Transfusion 1984 24 3 252 5.
4. Lalezari P. Alloimmune Neonatal Neutropenia. Amsterdam Elsevier 1984.
5. Lee GR Bithell TC Foerster J. Wintrobe's Clinical Haematology 9th edn. Lippincott Williams and Wilkins Pennsylvania USA 1993.
6. Lalezari P Radel E. Neutrophil-specific antigens: Immunology and clinical significance. Semin. Hematol. 1974 11 3 281 90.
7. Bux J. Challenges in the determination of clinically significant granulocyte antibodies and antigens. Transfus. Med. Rev. 1996 10 3 222 32.
8. Lucas G Rogers S De Haas M Porcelijn L Bux J. Report on the Fourth International Granulocyte Immunology Workshop: Progress toward quality assessment. Transfusion 2002 42 4 462 8.
9. Bux J Chapman J. Report on the Second International Granulocyte Serology Workshop. Transfusion 1997 37 977 83.
10. Askari S Miller J Chrysler G McCullough J. Impact of donor- and collection-related variables on product quality in ex utero cord blood banking. Transfusion 2005 45 2 189 94.
11. Wong A Yuen PM Li K Yu AL Tsoi WC. Cord blood collection before and after placental delivery: Levels of nucleated cells, haematopoietic progenitor cells, leukocyte subpopulations and macroscopic clots. Bone Marrow Transplant. 2001 27 2 133 8.
12. Zupanska B Uhrynowska M Guz K et al. The risk of antibody formation against HNA1a and HNA1b granulocyte antigens during pregnancy and its relation to neonatal neutropenia. Transfus. Med. 2001 11 377 82.
13. ISBT Working Party. Nomenclature of granulocyte alloantigens. Vox Sang. 1999 77 251.
14. von dem Borne AEGKr De Haas M Simcek S Porcelijn L van der Schoot CE. Platelet and neutrophil alloantigens in clinical medicine. Vox Sang. 1996 70 Suppl. 3 41 3.
15. Rodwell RL Gray PH Minchinton RM. Granulocyte colony stimulating factor treatment for alloimmune neonatal neutropenia. Arch. Dis. Child. 1996 75 1 57 8.
16. Fung YL Pitcher LA Willett JE et al. Alloimmune neonatal neutropenia linked to anti-HNA-4a. Transfus. Med. 2003 13 1 49 52.
17. Williamson LM Hackett G Rennie J et al. The natural history of fetomaternal alloimmunization to the platelet-specific antigen HPA-1a (PlA1, Zwa) as determined by antenatal screening. Blood 1998 92 7 2280 87.
18. Bussel J Kaplan C McFarland J. Recommendations for the evaluation and treatment of neonatal autoimmune and alloimmune thrombocytopenia. The Working Party on Neonatal Immune Thrombocytopenia of the Neonatal Hemostasis Subcommittee of the Scientific and Standardization Committee of the ISTH. Thromb. Haemost. 1991 65 5 631 4.