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Volumn 19, Issue 3, 2006, Pages 303-310

Physics of RNA and viral assembly

Author keywords

[No Author keywords available]

Indexed keywords

GENES; RNA; VIRUSES;

EID: 33645290922     PISSN: 12928941     EISSN: 1292895X     Source Type: Journal    
DOI: 10.1140/epje/i2005-10071-1     Document Type: Article
Times cited : (37)

References (32)
  • 5
    • 0004158830 scopus 로고    scopus 로고
    • edited by Wah Chiu, Roger M. Burnett, Robert L. Garcea (Oxford University Press, New York)
    • J. Johnson, R. Rueckert, in Structural Biology of Viruses, edited by Wah Chiu, Roger M. Burnett, Robert L. Garcea (Oxford University Press, New York, 1997).
    • (1997) Structural Biology of Viruses
    • Johnson, J.1    Rueckert, R.2
  • 6
    • 33645311582 scopus 로고    scopus 로고
    • note
    • Not only do small RNA viruses have nucleotide densities that are comparable to that of crystalline RNA, but there are examples where the nucleotide density even exceeds that of crystalline RNA, such as the Rhinovirus which has a packing density of 1.69 cubic angstrom per dalton.
  • 16
    • 33645279600 scopus 로고    scopus 로고
    • private communication
    • C. Knobler, private communication.
    • Knobler, C.1
  • 19
    • 33645285343 scopus 로고    scopus 로고
    • note
    • Actually, the edges of the dodecahedral cage in Figure 6 are low-curvature borders between the pyramids.
  • 24
    • 33645317934 scopus 로고    scopus 로고
    • note
    • The physical meaning of the negative slope for 〈ø〉 less than 〈ø〉* in terms of the pressure is that, for ξ less than R, the Gibbs free energy scales as the surface area of the shell. By Laplace's Law, this effective negative surface tension indeed should produce a negative pressure. However, in reality, the negative tension produced by the polymer adsorption is exactly cancelled by repulsion between the capsid proteins leading to a zero total surface tension (as in the Shulman criterion for surfactant bilayers). The actual pressure is thus zero for 〈ø〉 less than 〈ø〉*. For ξ greater than R, the Gibbs free energy no longer scales as the surface area and the capsid wall develops a true tension.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.