In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen

Clinical and Experimental Allergy

Volumn 36, Issue 4, 2006, Pages 531-542

  Wicklein, D ^a   Stocker M ^b   Klockenbring, T ^c   Huhn, M ^c   Wodrich, M ^a   Haas, H ^a   Becker, W M ^a   Barth, S ^c   Petersen, A ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

Author keywords

Allergen; Allergen toxin; Basophils; Hybridoma cells

Indexed keywords

ALLERGEN PH1 P 5B; ANTIGEN; BIOCHEMICAL MARKER; CD203C ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOTOXIN; INTERLEUKIN 4; POLLEN ANTIGEN; PROTEIN P5 ETA'; PSEUDOMONAS EXOTOXIN; UNCLASSIFIED DRUG;

ALLERGY; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BASOPHIL; CELL FATE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG TARGETING; EFFECTOR CELL; HUMAN; HUMAN CELL; HYBRIDOMA CELL CULTURE; IMMUNOTOXICITY; IN VITRO STUDY; INTERNALIZATION; MAST CELL; MOUSE; NONHUMAN; PHLEUM PRATENSE; PRIORITY JOURNAL; UPREGULATION;

ADP RIBOSE TRANSFERASES; ALLERGENS; ANIMALS; B-LYMPHOCYTES; BACTERIAL TOXINS; BASOPHILS; CELL LINE; CYTOTOXICITY TESTS, IMMUNOLOGIC; EXOTOXINS; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOTOXINS; LEUKOCYTES, MONONUCLEAR; MICE; MODELS, ANIMAL; PLANT PROTEINS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RESPIRATORY HYPERSENSITIVITY; RIBONUCLEASES; VIRULENCE FACTORS;

EID: 33645290788     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02461.x     Document Type: Article

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