Long-term prognosis of nonalcoholic fatty liver disease: Is pharmacological therapy actually necessary?

Journal of Gastroenterology and Hepatology (Australia)

Volumn 21, Issue 1 PART1, 2006, Pages 169-173

  Cinar, Kubilay ^a   Coban, Sahin ^a   Idilman, Ramazan ^a   Tuzun, Ali ^a   Sarioglu, Mustafa ^a   Bektas, Mehmet ^a   Erden, Esra ^a   Bozkaya, Hakan ^a   Ozden, Ali ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Liver; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Treatment

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; CLINICAL ARTICLE; DIABETES MELLITUS; DIET; DYSLIPIDEMIA; EXERCISE; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; JOGGING; LIVER FUNCTION TEST; LONG TERM CARE; MALE; NONALCOHOLIC FATTY LIVER; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROTHROMBIN TIME; STATISTICAL SIGNIFICANCE; THROMBOCYTE COUNT; WALKING;

EID: 33645241430     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2005.04221.x     Document Type: Article

References (21)

1. Alba LM Lindor K Non-alcoholic fatty liver disease AlimentPharmacolTher 2003 17 977 86
2. Yaunossi ZM Non-alcoholic fatty liver disease CurrGastroenterolRep 1999 1 57 62
3. Browning JD Szczepaniak LS Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity Hepatology 2004 40 1387 95
4. Teli MR James OFW Burt JA Bennet MK Day CP The natural history of non-alcoholic fatty liver: a follow-up study Hepatology 1995 22 1714 19
5. Matteoni CA Younossi ZM Gramlich T Boparai N Liu YC McCullough AJ Non-alcoholic fatty liver disease. A spectrum of clinical and pathological severity Gastroenterology 1999 116 1413 19
6. Angulo P Keach JC Batts KP et al. Independent predictors of liver fibrosis in patients with non-alcoholic steatohepatitis Hepatology 1999 30 1356 62
7. Kral JG Schaffner F Pierson RN Wang J Body fat topography as an independent predictor of fatty liver Metabolism 1993 42 548 51
8. Adams LA Sanderson S Lindor KD Angulo P The histological course of non-alcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies JHepatol 2005 42 132 8
9. Laurin J Lindor K Crippin J et al. Ursodeoxycholic acid or clofibrate in the treatment of non-alcoholic steatohepatitis: a pilot study Hepatology 1996 23 1464 7
10. Marchesini G Brizi M Bianchi G et al. Metformin in non-alcoholic steatohepatitis Lancet 2001 358 893 4
11. Basaranoglu M Acbay O Sonsuz A A controlled trial of gemfibrozil in the treatment of patients with non-alcoholic steatohepatitis JHepatol 1999 31 384
12. Caldwell SH Hespenheiden EE Redick JA et al. A pilot study of thiazolidinedione, troglitazone, in non-alcoholic steatohepatitis AmJGastroenterol 2001 96 519 25
13. Brunt EM Janney CG Di Bisceglie AM Neuschwander-Tetri BA Bacon BR Non-alcoholic steatohepatitis: a proposal for grading and staging the histological lesions AmJGastroenterol 1999 94 2467 74
14. Saadeh S Younossi ZM Remer EM et al. The utility of radiological imaging in nonalcoholic fatty liver disease Gastroenterology 2002 123 745 50
15. Ueno T Sugawara H Sujaku K et al. Therapeutic effects of restricted diet and exercise in obese patients with fatty liver JHepatol 1997 27 103 7
16. Kukkonen K Rauramaa R Siitonen O Hanninen O Physical training of obese middle-aged persons AnnClinRes 1982 34 80 5
17. World Health Organization. Obesity: Preventing and Managing the Global Epidemic Report of a WHO consultation on obesity. Geneva World Health Organization 1998
18. National Institute of Health, National Heart Lung and Blood Institute. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults - the evidence report ObesRes 1998 6 51S 209S
19. Dam-Larsen S Franzmann M Andersen IB et al. Long-term prognosis of fatty liver: risk of chronic liver disease and death Gut 2004 53 750 5
20. Cortez-Pinto H Baptista A Camilo ME De Moura MC Non-alcoholic steatohepatitis: a long-term follow-up study DigDisSci 2003 48 1909 13
21. Sheth SC Gordon FD Chopra S Non-alcoholic steatohepatitis AnnInternMed 1997 126 137 45