Myosin light chain kinase A is activated by cGMP-dependent and cGMP-independent pathways

FEBS Letters

Volumn 580, Issue 8, 2006, Pages 2059-2064

  Goldberg, Jonathan M ^a   Wolpin, Eric S ^a   Bosgraaf, Leonard ^b   Clarkson, Bryan K ^a   Van Haastert, Peter J M ^b   Smith, Janet L ^a  

^a BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

cGMP; Chemotaxis; Dictyostelium; Myosin; Phosphorylation; Regulatory light chain

Indexed keywords

CONCANAVALIN A; CYCLIC GMP; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE A; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVATION; GENE DISRUPTION; IN VIVO STUDY; LIGHT CHAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; CARRIER PROTEINS; CHEMOTAXIS; CONCANAVALIN A; CYCLIC GMP; CYTOKINESIS; DICTYOSTELIUM; ENZYME ACTIVATION; GENE DELETION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

DICTYOSTELIUM;

EID: 33645235492     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.008     Document Type: Article

References (28)

1. M. Affolter, and C.J. Weijer Signaling to cytoskeletal dynamics during chemotaxis Dev. Cell 9 2005 19 34
2. D. Wessels, D.R. Soll, D. Knecht, W.F. Loomis, A. De Lozanne, and J. Spudich Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain Dev. Biol. 128 1988 164 177
3. S. Yumura, and Y. Fukui Reversible cyclic AMP-dependent change in distribution of myosin thick filaments in Dictyostelium Nature 314 1985 194 196
4. S.L. Moores, J.H. Sabry, and J.A. Spudich Myosin dynamics in live Dictyostelium cells Proc. Natl. Acad. Sci. USA 93 1996 443 446
5. P.A. Clow, and J.G. McNally In vivo observations of myosin II dynamics support a role in rear retraction Mol. Biol. Cell 10 1999 1309 1323
6. C.H. Berlot, J.A. Spudich, and P.N. Devreotes Chemoattractant-elicited increases in myosin phosphorylation in Dictyostelium Cell 43 1985 307 314
7. C.H. Berlot, P.N. Devreotes, and J.A. Spudich Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity J. Biol. Chem. 262 1987 3918 3926
8. L.M. Griffith, S.M. Downs, and J.A. Spudich Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function J. Cell Biol. 104 1987 1309 1323
9. H. Zhang, D. Wessels, P. Fey, K. Daniels, R.L. Chisholm, and D.R. Soll Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity during Dictyostelium chemotaxis J. Cell. Sci. 115 2002 1733 1747
10. J.M. Mato, P.J.M. Van Haastert, F.A. Krens, E.H. Rhijnsburger, F.C.P.M. Dobbe, and T.M. Konijn Cyclic AMP and folic acid mediated cyclic GMP accumulation in Dictyostelium discoideum FEBS Lett. 79 1977 331 336
11. B. Wurster, K. Schubiger, U. Wick, and G. Gerisch Cyclic GMP in Dictyostelium discoideum FEBS Lett. 76 1977 141 144
12. J.M. Goldberg, L. Bosgraaf, P.J.M. Van Haastert, and J.L. Smith Identification of four candidate cGMP targets in Dictyostelium Proc. Natl. Acad. Sci. USA 99 2002 6749 6754
13. L. Bosgraaf, H. Russcher, J.L. Smith, D. Wessels, D.R. Soll, and P.J.M. Van Haastert A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium EMBO J. 21 2002 4560 4570
14. L. Bosgraaf, A. Waijer, R. Engel, A.J. Visser, D. Wessels, D. Soll, and P.J.M. van Haastert RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium J. Cell. Sci. 118 2005 1899 1910
15. J.L. Smith, L.A. Silveira, and J.A. Spudich Myosin light chain kinase (MLCK) gene disruption in Dictyostelium: a role for MLCK-A in cytokinesis and evidence for multiple MLCKs Proc. Natl. Acad. Sci. USA 93 1996 12321 12326
16. L.A. Silveira, J.L. Smith, J.L. Tan, and J.A. Spudich MLCK-A, an unconventional myosin light chain kinase from Dictyostelium, is activated by a cGMP-dependent pathway Proc. Natl. Acad. Sci. USA 95 1998 13000 13005
17. J.L. Smith, L.A. Silveira, and J.A. Spudich Activation of Dictyostelium myosin light chain kinase A by phosphorylation of Thr166 EMBO J. 15 1996 6075 6083
18. J.L. Tan, and J.A. Spudich Dictyostelium myosin light chain kinase: purification and characterization J. Biol. Chem. 265 1990 13818 13824
19. K.M. Pang, M.A. Lynes, and D.A. Knecht Variables controlling the expression level of exogenous genes in Dictyostelium Plasmid 41 1999 187 197
20. W. Nellen, S. Datta, C. Reymond, A. Sivertsen, S. Mann, T. Crowley, and R.A. Firtel Molecular biology in Dictyostelium: tools and applications Meth. Cell. Biol. 28 1987 67 100
21. J. Roelofs, and P.J.M. Van Haastert Characterization of two unusual guanylyl cyclases from Dictyostelium J. Biol. Chem. 277 2002 9167 9174
22. J. Roelofs, M. Meima, P. Schaap, and P.J.M. Van Haastert The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase EMBO J. 20 2001 4341 4348
23. J. Roelofs, H. Snippe, R.G. Kleineidam, and P.J.M. Van Haastert Guanylate cyclase in Dictyostelium discoideum with the topology of mammalian adenylate cyclase Biochem. J. 354 2001 697 706
24. A. De Lozanne, and J.A. Spudich Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination Science 236 1987 1086 1091
25. D. Knecht, and W.F. Loomis Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum Science 236 1987 1081 1086
26. F. Matsumura, G. Totsukawa, Y. Yamakita, and S. Yamashiro Role of myosin light chain phosphorylation in the regulation of cytokinesis Cell. Struct. Funct. 26 2001 639 644
27. B.D. Ostrow, P. Chen, and R.L. Chisholm Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells J. Cell. Biol. 127 1994 1945 1955
28. M. Sussman Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions J.A. Spudich Dictyostelium discoideum: Molecular Approaches to Cell Biology vol. 28 1987 Academic Press Inc. Orlando 9 30