Origin of neovascular structure in an early stage of hepatocellular carcinoma: Study of alpha-smooth muscle actin immunohistochemistry in serial thin sections of surgically resected cancer

Journal of Gastroenterology and Hepatology (Australia)

Volumn 21, Issue 1 PART1, 2006, Pages 183-190

  Ikeda, Kenji ^a   Kobayashi, Masahiro ^a   Saitoh, Satoshi ^a   Someya, Takashi ^a   Hosaka, Tetsuya ^a   Sezaki, Hitomi ^a   Suzuki, Yoshiyuki ^a   Suzuki, Fumitaka ^a   Akuta, Norio ^a   Arase, Yasuji ^a   Kumada, Hiromitsu ^a  

^a TORANOMON HOSPITAL   (Japan)

Author keywords

Alpha smooth muscle actin; Hepatocellular carcinoma; Neovascularity; Non triadal vessel; Portal vein

Indexed keywords

ACTIN ANTIBODY; ALPHA SMOOTH MUSCLE ACTIN; CARBON DIOXIDE; PARAFFIN;

ADULT; AGED; ARTERIAL BLOOD; ARTERY; ARTICLE; BILE DUCT; CANCER STAGING; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIGITAL SUBTRACTION ANGIOGRAPHY; ECHOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER ARTERIOGRAPHY; LIVER CELL CARCINOMA; MALE; NEOVASCULARIZATION (PATHOLOGY); PORTAL VEIN; PRIORITY JOURNAL; STAINING; TUMOR DIFFERENTIATION;

EID: 33645234680     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04234.x     Document Type: Article

References (31)

1. Okuda K Obata H Jinnouchi S et al. Angiographic assessment of gross anatomy of hepatocellular carcinoma: comparison of celiac angiograms and liver pathology in 100 cases Radiology 1977 123 21 9
2. Cooper JN. Imaging and hepatocellular carcinoma GastroenterolClinNorth Am 1987 16 591 602
3. Chuang VP. Hepatic tumor angiography. A subject review Radiology 1983 148 633 9
4. Shinagawa T Ohto M Kimura K et al. Diagnosis and clinical features of small hepatocellular carcinoma with emphasis on the utility of real-time ultrasonography. A study in 51 patients Gastroenterology 1984 86 495 502
5. Sonoda T Shirabe K Takenaka K Kanematsu T Yasumori K Sugimachi K. Angiographically undetected small hepatocellular carcinoma: clinicopathological characteristics, follow-up, and treatment Hepatology 1989 10 1003 7
6. Takahashi K Saito K Tamura K et al. Hepatic neoplasms: detection with hepatoportal subtraction angiography - a new technique of DSA Radiology 1990 177 243 8
7. Ikeda K Saitoh S Koida I et al. Diagnosis and follow-up of small hepatocellular carcinoma with selective intra-arterial digital subtraction angiography Hepatology 1993 17 1003 7
8. Ikeda K Saitoh S Koida I et al. Imaging diagnosis of small hepatocellular carcinoma Hepatology 1994 20 82 7
9. Honda H Tajima T Taguchi K et al. Recent developments in imaging diagnostics for HCC: CT arteriography and CT arterioportography evaluation of vascular changes in premalignant and malignant hepatic nodules JHepatobiliary PancreatSurg 2000 7 245 51
10. Hirano K Kondo Y Teratani T et al. Hepatocellular carcinoma depicted as hypoattenuation on CT hepatic arteriography (CTA) and hyperattenuation on CT during arterial portography (CTAP) JGastroenterol 2001 36 346 9
11. Hayashi M Matsui O Ueda K Kawamori Y Gabata T Kadoya M. Progression to hypervascular hepatocellular carcinoma: correlation with intranodular blood supply evaluated with CT during intraarterial injection of contrast material Radiology 2002 225 143 9
12. Yamamoto K Shiraki K Deguchi M et al. Diagnosis of hepatocellular carcinoma using digital subtraction imaging with contrast agent, Levovist: comparison with helical CT, digital subtraction angiography, and US angiography OncolRes 2002 9 789 92
13. Koda M Mastsunaga Y Ueki M et al. Qualitative assessment of tumor vascularity in hepatocellular carcinoma by contrast-enhanced coded ultrasound: comparison with arterial phase of dynamic CT and conventional color/power Doppler ultrasound EurRadiol 2004 14 1100 8
14. Ikeda K Saitoh S Suzuki Y et al. Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle actin in small hepatocellular carcinoma JGastroenterolHepatol 1998 13 1266 73
15. Morinaga S Imada T Shimizu A et al. Angiogenesis in hepatocellular carcinoma as evaluated by alpha-smooth muscle actin immunohistochemistry Hepatogastroenterology 2001 48 224 8
16. International Working Party. Terminology of nodular hepatocellular lesions Hepatology 1995 22 983 93
17. Edmondson HA Steiner PE. Primary carcinoma of the liver. A study of 100 cases among 48 9 00 necropsies Cancer 1954 7 462 503
18. Skalli O Ropraz P Trzeciak A Benzonznz G Gillessen D Gabbiani G. A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation JCell Biol 1986 2787 96
19. Schmitt-Graff A Kruger S Bochard F Gabbiani G Denk H. Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers AmJPathol 1991 138 1233 42
20. Johnson SJ Hines JE Burt AD. Phenotypic modulation of perisinusoidal cells following acute liver injury: a quantitative analysis IntJExpPathol 1992 73 765 72
21. Yu E Choe C Gong G Lee I. Expression of alpha-smooth muscle actin in liver diseases JKorean MedSci 1993 8 367 73
22. Hines JE Johnson SJ Burt AD. In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury AmJPathol 1993 142 51 8
23. Himeno H Enzan H Saibara T Onishi S Yamamoto Y. Hitherto unrecognized arterioles within hepatocellular carcinoma JPathol 1994 174 217 22
24. Terada T Nakanuma Y. Arterial elements and perisinusoidal cells in borderline hepatocellular nodules and small hepatocellular carcinomas Histopathology 1995 27 333 9
25. Nakano M Saito A Yamamoto M Doi M Takasaki K. Stromal and blood vessel wall invasion in well-differentiated hepatocellular carcinoma Liver 1997 17 41 6
26. Matsui O Kadoya M Suzuki M et al. Work in progress: dynamic sequential computed tomography during portography in the detection of hepatic neoplasms Radiology 1983 146 721 7
27. 2 microbubbles Radiology 1986 161 701 5
28. Maksan SM Paulo H Ryschich E et al. In vivo assessment of angioarchitecture and microcirculation in experimental liver cancer: a new model in rats DigDisSci 2003 48 279 90
29. Chen WX Min PQ Song B Xiao BL Liu Y Ge YH. Single-level dynamic spiral CT of hepatocellular carcinoma: correlation between imaging features and density of tumor microvessels World JGastroenterol 2004 10 67 72
30. Ryschich E Schmidt E Maksan SM Klar E Schmidt J. Expansion of endothelial surface by an increase of vessel diameter during tumor angiogenesis in experimental and hepatocellular and pancreatic cancer World JGastroenterol 2004 10 3171 4
31. Kanematsu M Semelka RC Leonardou P et al. Angiogenesis in hepatocellular nodules: correlation of MR imaging and vascular endothelial growth factor JMagnResonImaging 2004 20 426 34