Age-related changes in trabecular bone microstructures: Global and local morphometry

Osteoporosis International

Volumn 17, Issue 4, 2006, Pages 616-626

  Stauber, M ^a   Muller R ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Age related changes; Local morphometry; Osteoporosis; Trabecular bone; Trabecular plates; Trabecular rods

Indexed keywords

AGED; AGING; ANALYSIS OF VARIANCE; ANALYTIC METHOD; ARTICLE; AUTOPSY; BONE DENSITY; BONE PLATE; BONE STRUCTURE; CONTROLLED STUDY; FEMALE; FEMUR HEAD; FRACTURE; HUMAN; HUMAN TISSUE; LINEAR SYSTEM; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MORPHOMETRICS; OSTEOLYSIS; PARAMETERS OF MEASUREMENT AND ANALYSIS; PATHOGENESIS; PERFORATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEX DIFFERENCE; THICKNESS; TRABECULAR BONE;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CADAVER; FEMALE; FEMUR HEAD; HUMANS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED;

EID: 33645231999     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-005-0025-6     Document Type: Article

References (70)

1. Beck JS, Nordin BE (1960) Histological assessment of osteoporosis by iliac crest biopsy. J Pathol Bacteriol 80:391-397
2. Caldwell RA (1962) Observations on the incidence, aetiology, and pathology of senile osteoporosis. J Clin Pathol 15:421-431
3. Lindahl O, Lindgren AG (1962) Grading of osteoporosis in autopsy specimens. A new method. Acta Orthop Scand 32:85-100
4. Riggs BL (1991) Overview of osteoporosis. West J Med 154 (1):63-77
5. Consensus development conference (1991) Prophylaxis and treatment of osteoporosis (1991). Am J Med 90(1):107-110
6. Consensus development conference (1993) Diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med 94(6):646-650
7. Consensus Development Conference (2000) Osteoporosis prevention, diagnosis, and therapy. NIH consensus statement 17 (1):1-45
8. Trotter M, Broman GE, Peterson RR (1960) Densities of bones of white and Negro skeletons. Am J Orthop 42-A:50-58
9. Bromley RG, Dockum NL, Arnold JS, Jee WS (1966) Quantitative histological study of human lumbar vertebrae. J Gerontol 21(4):537-543
10. Chalmers J, Weaver JK (1966) Cancellous bone: its strength and changes with aging and an evaluation of some methods for measuring its mineral content. II. An evaluation of some methods for measuring osteoporosis. J Bone Joint Surg Am 48 (2):299-308
11. Dunnill MS, Anderson JA, Whitehead R (1967) Quantitative histological studies on age changes in bone. J Pathol Bacteriol 94(2):275-291
12. Wakamatsu E, Sissons HA (1969) The cancellous bone of the iliac crest. Calcif Tissue Res 4(2):147-61
13. Ellis HA, Peart KM (1972) Quantitative observations on mineralized and non-mineralized bone in the iliac crest. J Clin Pathol 25(4):277-86
14. Arnold JS, Wei LT (1972) Quantitative morphology of vertebral trabecular bone. In: Stover B, Jee WS (eds) Radiobiology of plutonium, JW Press, Salt Lake City, pp 333-354
15. Merz WA, Schenk RK (1970) Quantitative structural analysis of human cancellous bone. Acta Anat (Basel) 75(1):54-66
16. Melsen F, Melsen B, Mosekilde L, Bergmann S (1978) Histomorphometric analysis of normal bone from the iliac crest. Acta Pathol Microbiol Scand, A 86(1):70-81
17. Vedi S, Compston JE, Webb A, Tighe JR (1982) Histomorphometric analysis of bone biopsies from the iliac crest of normal British subjects. Metab Bone Dis Relat Res 4(4):231-236
18. Atkinson PJ (1967) Variation in trabecular structure of vertebrae with age. Calcif Tissue Res 1(1):24-32
19. Carter DR, Hayes WC (1977) The compressive behavior of bone as a two-phase porous structure. J Bone Joint Surg Am 59 (7):954-962
20. Rice JC, Cowin SC, Bowman JA (1988) On the dependence of the elasticity and strength of cancellous bone on apparent density. J Biomech 21(2):155-168
21. Hui SL, Slemenda CW, Johnston CC, Jr (1988) Age and bone mass as predictors of fracture in a prospective study. J Clin Invest 81(6):1804-1809
22. Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS (1983) Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss. J Clin Invest 72(4):1396-1409
23. Kleerekoper M, Villanueva AR, Stanciu J, Rao DS, Parfitt AM (1985) The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int 37(6):594-597
24. Parfitt AM (1984) Age-related structural changes in trabecular and cortical bone: cellular mechanisms and biomechanical consequences. Calcif Tissue Int 36 (Suppl 1):S123-8
25. Mosekilde L (1988) Age-related changes in vertebral trabecular bone architecture-assessed by a new method. Bone 9(4):247-250
26. Mosekilde L (1989) Sex differences in age-related loss of vertebral trabecular bone mass and structure-biomechanical consequences. Bone 10(6):425-432
27. Thomsen JS, Ebbesen EN, Mosekilde LI (2002) Age-related differences between thinning of horizontal and vertical trabeculae in human lumbar bone as assessed by a new computerized method. Bone 31(1):136-142
28. Bergot C, Laval-Jeantet AM, Preteux F, Meunier A (1988) Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis. Calcif Tissue Int 43(3):143-149
29. McCalden RW, McGeough JA, Court-Brown CM (1997) Age-related changes in the compressive strength of cancellous bone. The relative importance of changes in density and trabecular architecture. J Bone Joint Surg Am 79(3):421-427
30. Weinstein RS, Hutson MS (1987) Decreased trabecular width and increased trabecular spacing contribute to bone loss with aging. Bone 8(3):137-142
31. Rüegsegger P, Koller B, Müller R (1996) A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int 58(1):24-29
32. Müller R, Hildebrand T, Rüegsegger P (1994) Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys Med Biol 39 (1):145-164
33. Müller R (2002) The Zürich experience: one decade of three-dimensional high-resolution computed tomography. Top Magn Reson Imaging 13(5):307-322
34. Wehrli FW, Saha PK, Gomberg BR, Song HK, Snyder PJ, Benito M, Wright A, Weening R (2002) Role of magnetic resonance for assessing structure and function of trabecular bone. Top Magn Reson Imaging 13(5):335-355
35. Majumdar S (1998) A review of magnetic resonance (MR) imaging of trabecular bone micro-architecture: contribution to the prediction of biomechanical properties and fracture prevalence. Technol Health Care 6(5-6):321-327
36. Majumdar S (2002) Magnetic resonance imaging of trabecular bone structure. Top Magn Reson Imaging 13(5):323-334
37. Hildebrand T, Rüegsegger P (1997) A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc 185:67-75
38. Hildebrand T, Rüegsegger P (1997) Quantification of bone microarchitecture with the structure model index. Comput Methods Biomech Biomed Eng 1(1):15-23
39. Jinnai H, Watashiba H, Kajihara T, Nishikawa Y, Takahashi M, Ito M (2002) Surface curvatures of trabecular bone microarchitecture. Bone 30(1):191-194
40. Odgaard A, Gundersen HJ (1993) Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions. Bone 14(2):173-182
41. Ding M (2000) Age variations in the properties of human tibial trabecular bone and cartilage. Acta Orthop Scand 292:1-45
42. Ding M, Odgaard A, Linde F, Hvid I (2002) Age-related variations in the microstructure of human tibial cancellous bone. J Orthop Res 20(3):615-621
43. Kinney JH, Ladd AJ (1998) The relationship between three-dimensional connectivity and the elastic properties of trabecular bone. J Bone Miner Res 13(5):839-845
44. Stauber M, Nazarian A, Müller R (2002) Element based morphometric characterization of trabecular bone. Trans Europ Orthop Res Soc 12, pp O89
45. Stauber M, Rapillard L, Zysset PK, Müller R (2003) Element based morphometry - a new tool for the assessment of mechanostructure relationships in trabecular bone. Trans Orthop Res Soc 28:109 New Orleans
46. Stauber M, Müller R (2006) Volumetric spatial decomposition of trabecular bone into rods and plates - A new method for local bone morphometry. Bone in press
47. Hildebrand T, Laib A, Müller R, Dequeker J, Rüegsegger P (1999) Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res 14(7):1167-1174
48. Dequeker J (1994) Assessment of quality of bone in osteoporosis-BIOMED I: fundamental study of relevant bone. Clin Rheumatol 13 (Suppl 1):7-12
49. Melton LJ, 3rd (2000) Who has osteoporosis? A conflict between clinical and public health perspectives. J Bone Miner Res 15(12):2309-2314
50. Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359(9319):1761-1767
51. Aerssens J, Boonen S, Joly J, Dequeker J (1997) Variations in trabecular bone composition with anatomical site and age: potential implications for bone quality assessment. J Endocrinol 155(3):411-421
52. Dequeker J, Boonen S, Breemans S (1995) Assessment of quality of bone in osteoporosis: clinical characteristics of patient material. Clin Rheumatol 14:596
53. Müller R, Rüegsegger P (1997) Micro-tomographic imaging for the nondestructive evaluation of trabecular bone architecture. Stud Health Technol Inform 40:61-79
54. Hahn M, Vogel M, Pompesius-Kempa M, Delling G (1992) Trabecular bone pattern factor - a new parameter for simple quantification of bone microarchitecture. Bone 13(4):327-330
55. Bernard TM, Manzanera A (1999) Improved Low Complexity Fully Parallel Thinning Algorithm 10th International Conference on Image Analysis and Processing (ICIAP '99), Venice, Italy
56. Manzanera A, Bernard TM, Prêteux F, Longuet B (1999) Medial faces from a concise 3D thinning algorithm International Conference on Computer Vision (ICCV '99), Kerkyra, Greece, pp 337-343
57. Saha PK, Chaudhuri BB (1996) 3D digital topology under binary transformation with applications. Comput Vis Image Underst 63(3):418-429
58. Cleveland WS (1979) Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc 74(368):829-836
59. Cleveland WS (1981) Lowess - a program for smoothing scatterplots by robust locally weighted regression. Am Stat 35 (1):54-54
60. Ding M, Hvid I (2000) Quantification of age-related changes in the structure model type and trabecular thickness of human tibial cancellous bone. Bone 26(3):291-295
61. Cummings SR, Black DM, Nevitt MC, Browner WS, Cauley JA, Genant HK, Mascioli SR, Scott JC, Seeley DG, Steiger P, et al. (1990) Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. JAMA 263(5):665-668
62. Riggs BL, Melton Iii LJ, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S (2004) Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res 19(12):1945-1954
63. Parfitt AM (1989) Plasma calcium control at quiescent bone surfaces: a new approach to the homeostatic function of bone lining cells. Bone 10(2):87-88
64. Müller R (2005) Long-term prediction of three-dimensional bone architecture in simulations of pre-, peri- and post-menopausal microstructural bone remodeling. Osteoporos Int 16 (Suppl 2):S25-S35
65. Hayes WC, Carter DR (1976) Postyield behavior of subchondral trabecular bone. J Biomed Mater Res 10(4):537-544
66. Turner CH (1989) Yield behavior of bovine cancellous bone. J Biomech Eng 111(3):256-260
67. Michel MC, Guo XD, Gibson LJ, McMahon TA, Hayes WC (1993) Compressive fatigue behavior of bovine trabecular bone. J Biomech 26(4-5):453-463
68. Müller R, Gerber SC, Hayes WC (1998) Micro-compression: a novel technique for the nondestructive assessment of local bone failure. Technol Health Care 6(5-6):433-444
69. Nazarian A, Müller R (2004) Time-lapsed microstructural imaging of bone failure behavior. J Biomech 37(1):55-65
70. Gibson LJ (2005) Biomechanics of cellular solids. J Biomech 38(3):377-399