Effective treatment with cyclosporine A of a child with systemic lupus erythematosus resistant to cyclophosphamide pulse therapy

Tohoku Journal of Experimental Medicine

Volumn 208, Issue 4, 2006, Pages 355-359

  Suzuki, Koichi ^a   Tanaka, Hiroshi ^a   Tsugawa, Koji ^a   Ito, Eturo ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Cyclosporine A; Intermittent intravenous cyclophosphamide pulse resistant; Systemic lupus erythematosus

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DOUBLE STRANDED DNA ANTIBODY; METHYLPREDNISOLONE; MIZORIBINE; PREDNISOLONE;

ANTIBODY TITER; AREA UNDER THE CURVE; ARTICLE; CASE REPORT; CLINICAL EFFECTIVENESS; CLINICAL FEATURE; COMPLEMENT BLOOD LEVEL; COUGHING; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; DRUG PULSE THERAPY; ECHOCARDIOGRAPHY; ELECTRON MICROSCOPY; FATIGUE; FEMALE; FEVER; GLUCOSURIA; HUMAN; HYPOCOMPLEMENTEMIA; JAPAN; KIDNEY BIOPSY; LONG TERM CARE; LUPUS ERYTHEMATOSUS NEPHRITIS; OBESITY; OSTEOPOROSIS; PANCYTOPENIA; PERICARDIAL EFFUSION; PERICARDITIS; PRESCHOOL CHILD; REMISSION; SYSTEMIC LUPUS ERYTHEMATOSUS;

CHILD; CYCLOPHOSPHAMIDE; CYCLOSPORINE; DRUG RESISTANCE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, INTRAVENOUS; LUPUS ERYTHEMATOSUS, SYSTEMIC; PULSE THERAPY, DRUG; TREATMENT OUTCOME;

EID: 33645230413     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.208.355     Document Type: Article

References (14)

1. Balow, J.E. & Austin, H.A. (2004) Treatment of proliferative lupus nephritis. Am. J. Kidney Dis., 43, 383-385.
2. Boletis, J., Ioannidis, J. & Boki, K. (1999) Intravenous immunoglobulin compared with cyclophosphamide for proliferative lupus nephritis. Lancet, 354, 569-570.
3. Boumpas, D.T., Austin, H.A., Vaughn, E.M., Klippel, J.H., Steinberg, A.D., Yarboro, C.H. & Balow, J.E. (1992) Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet, 340, 741-745.
4. Caccavo, D., Lagana, B., Mitterhofer, A.P., Ferri, G.M., Afeltra, A., Amoroso, A. & Bonomo, L. (1997) Long-term treatment of systemic lupus erythematosus with cyclosporine A. Arthritis Rheum., 40, 27-35.
5. Ferrario, L., Bellone, M., Bozzolo, E., Baldissera, E. & Sabbadini, M.D. (1999) Remission from lupus nephritis resistant to cyclophosphamide after additional treatment with cyclosporine A. Rheumatol., 39, 218-220.
6. Gourley, M.F., Austin, H.A., III., Scott, D., Yarboro, C.H., Vaughan E.M., Muir, J., Boumpas, D.T., Klippel, J.H., Balow, J.E. & Steinberg, A.D. (1996) Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomised, controlled trial. Ann. Intern. Med., 125, 549-557.
7. Griffiths, B. & Emery, P. (2001) The treatment of lupus with cyclosporine A. Lupus, 10, 165-170.
8. Lebman, T.A. & Onel, K. (2000) Intermittent intravenous cyclophosphamide arrests progression of the renal chronicity index in childhood systemic lupus erythematosus. J. Pediatr., 136, 243-247.
9. Lee, Y.M., Fujiwara, J., Munakata, Y., Ishii, T., Sugawara, A., Kaku, M., Kokubun, S., Sasaki, T. & Funato, T. (2004) A mutation of the glucocorticoid receptor gene in patients with systemic lupus erythematosus. Tohoku J. Exp. Med., 203, 69-76.
10. 2 point monitoring of low-dose cyclosporine A given as a single daily dose in children with steroid-dependent relapsing nephritic syndrome. Clin. Nephrol., 64, 258-263.
11. Sakano, T., Ohta, T., Kinoshita, Y., Fujiwara, M. & Wakai, M. (2004) Treatment of steroid-resistant systemic lupus erythematosus with extremely low dose of cyclosporine A. Pediatr. Int., 46, 468-470.
12. Tanaka, H., Tateyama, T. & Waga, S. (2001) Methylprednisolone pulse therapy in Japanese children with severe lupus nephritis. Pediatr. Nephrol., 16, 817-819.
13. Tanaka, H., Suzuki, K., Nakahata, T., Tsugawa, K., Ito, E. & Waga, S. (2003) Mizoribine oral pulse therapy for patients with disease flare of lupus nephritis. Clin. Nephrol., 60, 390-394.
14. Uchida, K., Tominaga, Y., Haba, T., Katayama, A., Matsuoka, S., Goto, N., Ueki, T., Kimata, T., Takeda, A., Morozumi, K., Takagi, H. & Nakao, A. (2004) Clinical success of Neoral absorption profile. Transplant Proc., 36, 461-464.