Erythropoietin activates caspase-3 and downregulates CAD during erythroid differentiation in TF-1 cells - A protection mechanism against DNA fragmentation

FEBS Letters

Volumn 580, Issue 8, 2006, Pages 1965-1970

  Lui, Julian Chun Kin ^a   Kong, Siu Kai ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; DNA fragmentation; Erythroid differentiation

Indexed keywords

CASPASE 3; CASPASE ACTIVATED DEOXYRIBONUCLEASE; DEOXYRIBONUCLEASE; DNA FRAGMENT; ENZYME INHIBITOR; INHIBITOR OF CASPASE ACTIVATED DEOXYRIBONUCLEASE; PHOSPHATIDYLSERINE; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYMATIC ASSAY; ENZYME ACTIVATION; ENZYME DEGRADATION; ERYTHROID CELL; ERYTHROPOIESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CELLS, CULTURED; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; DOWN-REGULATION; ENZYME ACTIVATION; ERYTHROID CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN, RECOMBINANT; GENE EXPRESSION; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; RNA, MESSENGER;

EID: 33645225982     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.02.059     Document Type: Article

References (24)

1. P.K. Ho, and C.J. Hawkins Mammalian initiator apoptotic caspases FEBS J. 272 2005 5436 5453
2. G.W. Carlile, D.H. Smith, and M. Wiedmann Caspase-3 has a nonapoptotic function in erythroid maturation Blood 103 2004 4310 4316
3. U. Testa Apoptotic mechanisms in the control of erythropoiesis Leukemia 18 2004 1176 1199
4. Y. Zermati, C. Garrido, S. Amsellem, S. Fishelson, D. Bouscary, F. Valensi, B. Varet, E. Solary, and O. Hermine Caspase activation is required for terminal erythroid differentiation J. Exp. Med. 193 2001 247 254
5. S. Nagata DNA degradation in development and programmed cell death Annu. Rev. Immunol. 23 2005 853 875
6. S. Launay, O. Hermine, M. Fontenay, G. Kroemer, E. Solary, and C. Garrido Vital functions for lethal caspases Oncogene 24 2005 5137 5148
7. A. Kolbus, S. Pilat, Z. Husak, E.M. Deiner, G. Stengl, H. Beug, and M. Baccarini Raf-1 antagonizes erythroid differentiation by restraining caspase activation J. Exp. Med. 196 2002 1347 1353
8. R. De Maria, U. Testa, L. Luchetti, A. Zeuner, G. Stassi, E. Pelosi, R. Riccioni, N. Felli, P. Samoggia, and C. Peschle Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis Blood 93 1999 796 803
9. R. De Maria, A. Zeuner, A. Eramo, C. Domenichelli, D. Bonci, F. Grignani, S.M. Srinivasula, E.S. Alnemri, U. Testa, and C. Peschle Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 Nature 401 1999 489 493
10. P.A. Gregoli, and M.C. Bondurant Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors J. Cell Physiol. 178 1999 133 143
11. S.M. Jacobs-Helber, and S.T. Sawyer Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines Blood 104 2004 670 696
12. M. Uchida, T. Watanabe, M. Kunitama, M. Mori, S. Kikuchi, K. Yoshida, K. Kirito, T. Nagai, K. Ozawa, and N. Komatsu Erythropoietin overcomes imatinib-induced apoptosis and induces erythroid differentiation in TF-1/bcr-abl cells Stem Cells 22 2004 609 616
13. M.Y. Zhang, S.C. Sun, L. Bell, and B.A. Miller NF-kappa B transcription factors are involved in normal erythropoiesis Blood 91 1998 4136 4144
14. M.J. Koury, S.T. Sawyer, and S.J. Brandt New insights into erythropoiesis Curr. Opin. Hematol. 9 2002 93 100
15. M. Garcia-Calvo, E.P. Peterson, B. Leiting, R. Ruel, D.W. Nicholson, and N.A. Thornberry Inhibition of human caspases by peptide-based and macromolecular inhibitors J. Biol. Chem. 273 1998 32608 32613
16. A. Rosen, and L. Casciola-Rosen Macromolecular substrates for the ICE-like proteases during apoptosis J. Cell Biochem. 64 1997 50 54
17. A. Zeuner, A. Eramo, U. Testa, N. Felli, E. Pelosi, G. Mariani, S.M. Srinivasula, E.S. Alnemri, G. Condorelli, C. Peschle, and R. De Maria Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1 Cell Death Differ. 10 2003 905 913
18. R.V. Talanian, C. Quinlan, S. Trautz, M.C. Hackett, J.A. Mankovich, D. Banach, T. Ghayur, K.D. Brady, and W.W. Wong Substrate specificities of caspase family proteases J. Biol. Chem. 272 1997 9677 9682
19. M. Enari, H. Sakahira, H. Yokoyama, K. Okawa, A. Iwamatsu, and S. Nagata A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD Nature 391 1998 43 50
20. H. Sakahira, M. Enari, and S. Nagata Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis Nature 391 1998 96 99
21. X. Liu, H. Zou, C. Slaughter, and X. Wang DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis Cell 89 1997 175 184
22. D. Lechardeur, L. Drzymala, M. Sharma, D. Zylka, R. Kinach, J. Pacia, C. Hicks, N. Usmani, J.M. Rommens, and G.L. Lukacs Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD) J. Cell Biol. 150 2000 321 334
23. P. Widlak The DFF40/CAD endonuclease and its role in apoptosis Acta Biochim. Pol. 47 2000 1037 1044
24. D.A. Le, Y. Wu, Z. Huang, K. Matsushita, N. Plesnila, J.C. Augustinack, B.T. Hyman, J. Yuan, K. Kuida, R.A. Flavell, and M.A. Moskowitz Caspase activation and neuroprotection in caspase-3-deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation Proc. Natl. Acad. Sci. USA 99 2002 15188 15193