Sleep apnoea-hypopnoea index is an independent predictor of high-sensitivity C-reactive protein elevation

Respiration

Volumn 73, Issue 2, 2006, Pages 243-246

  Boudjeltia, Karim Zouaoui ^a   Van Meerhaeghe, Alain ^b   Doumit, Sonia ^b   Guillaume, Michel ^b   Cauchie, Philippe ^a   Brohée, Dany ^a   Vanhaeverbeek, Michel ^a   Kerkhofs, Myriam ^b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Atherosclerosis; C reactive protein; Cardiovascular disease; Cardiovascular risk; High sensitivity C reactive protein; Hypopnoea index; Sleep apnoea

Indexed keywords

C REACTIVE PROTEIN; LIPID;

ADULT; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; FEMALE; HUMAN; HYPERTENSION; LEUKOCYTE; LINEAR REGRESSION ANALYSIS; MALE; MULTIVARIATE ANALYSIS; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SLEEP APNEA SYNDROME; SMOKING HABIT; STEP WISE MULTIPLE REGRESSION; UNIVARIATE ANALYSIS;

C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYSOMNOGRAPHY; SEVERITY OF ILLNESS INDEX; SLEEP APNEA SYNDROMES;

EID: 33645225972     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090201     Document Type: Article

References (17)

1. Peker Y, Hedner J, Kraiczi H, Loth S: Respiratory disturbance index A independent predictor of mortality in coronary artery disease. Am J Respir Crit Care Med 2000;162:81-86.
2. Poredos P: Endothelial dysfunction in the pathogenesis of atherosclerosis. Int Angiol 2002;21:109-116.
3. Ridker PM: High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation 2001;103:1813-1818.
4. Shamsuzzaman ASM, Winnicki M, Lanfranchi P, Wolk R, Kara T, Accurso V, Somers VK: Elevated C-reactive protein in patients with obstructive sleep apnea. Circulation 2002;105:2462-2464.
5. Guilleminault C, Kirisoglu C, Ohayon M: C-reactive protein and sleep-disordered breathing. Sleep 2004;27:1507-1511.
6. Wang Y, Yang H, Dong M: Study on the levels of C-reactive protein and fibrinolytic activity in patients with obstructive sleep apnea syndrome. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2004;18:147-148.
7. Tauman R, Ivanenko A, O'Brien LM, Gozal D: Plasma C-reactive protein levels among children with sleep-disordered breathing. Pediatrics 2004;113:564-569.
8. Kaditis AG, Alexopoulos EI, Kalampouka E, Kostadima E, Germenis A, Zintzaras E, Gourgoulianis K: Morning levels of C-reactive protein in children with obstructive sleep disordered breathing. Am J Respir Crit Care Med 2005;171:282-286.
9. Yokoe T, Minoguchi K, Matsuo H, Oda N, Minoguchi H, Yoshino G, Hirano T, Adachi M: Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 2003;107:1129-1134.
10. Larkin EK, Rosen CL, Kirchner HL, Storfer-Isser A, Emancipator JL, Johnson NL, Zambito AM, Tracy RP, Jenny NS, Redline S: Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation 2005;111:1978-1984.
11. Olivares R, Ducimetiere P, Claude JR: Monocyte count: a risk factor for coronary heart disease? Am J Epidemiol 1993;137:49-53.
12. Scols AM, Buurman WA, Staal-van den Brekel AJ, Dentener MA, Wouters EF: Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease. Thorax 1996;51:819-824.
13. Fröhlich M, Imhof AA, Berg G: Association between C-reactive protein and features of the metabolic syndrome. Diabetes Care 2000;23:1835-1839.
14. Cheng TO: Could elevated C-reactive protein in patients with obstructive sleep apnea be due to obesity per se? Circulation 2003;107:9.
15. Ridker PM, Hennekens CH, Buring JE, Rifai N: C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000;342:836-843.
16. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR: Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002;347:1557-1565.
17. Hatipoglu U, Rubinstein I: Inflammation and obstructive sleep apnea syndrome pathogenesis: a working hypothesis. Respiration 2003;70:665-671.