Partial delipidation improves the T-cell antigenicity of hepatitis B virus surface antigen

Journal of Virology

Volumn 80, Issue 7, 2006, Pages 3506-3514

  Desombere, Isabelle ^a   Willems, Annick ^a   Gijbels, Yvonne ^a   Leroux Roels, Geert ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; LIPID; VIRUS ANTIGEN; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; INBRED STRAIN; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEROLOGY; T LYMPHOCYTE; VIRUS HEPATITIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL PROLIFERATION; CENTRIFUGATION, DENSITY GRADIENT; DETERGENTS; DNA, VIRAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FREUND'S ADJUVANT; GLUCOSIDES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; INJECTIONS, INTRAMUSCULAR; MALE; MEMBRANE LIPIDS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MIDDLE AGED; RECOMBINANT PROTEINS; T-LYMPHOCYTES;

ANIMALIA; DNA VIRUSES; HEPATITIS B VIRUS;

EID: 33645222014     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.7.3506-3514.2006     Document Type: Article

References (36)

1. Berting, A., J. Hahnen, M. Kroger, and W. H. Gerlich. 1995. Computer-aided studies on the spatial structure of the small hepatitis B surface protein. Intervirology 38:8-15.
2. Brewer, J. M., C. W. Roberts, W. H. Stimson, and J. Alexander. 1995. Accurate determination of adjuvant-associated protein or peptide by ninhydrin assay. Vaccine 13:1441-1444.
3. Celis, E., and R. W. Karr. 1989. Presentation of an immunodominant T-cell epitope of hepatitis B surface antigen by the HLA-DPw4 molecule. J. Virol. 63:747-752.
4. Desombere, I., T. Cao, Y. Gijbels, and G. Leroux-Roels. 2005. Non-responsiveness to hepatitis B surface antigen vaccines is not caused by defective antigen presentation or a lack of B7 co-stimulation. Clin. Exp. Immunol. 140:126-137.
5. Desombere, I., Y. Gijbels, A. Verwulgen, and G. Leroux-Roels. 2000. Characterization of the T cell recognition of hepatitis B surface antigen (HBsAg) by good and poor responders to hepatitis B vaccines. Clin. Exp. Immunol. 122:390-399.
6. Desombere, I., P. Hauser, R. Rossau, J. Paradijs, and G. Leroux-Roels. 1995. Nonresponders to hepatitis B vaccine can present envelope particles to T lymphocytes. J. Immunol. 154:520-529.
7. Desombere, I., A. Willems, and G. Leroux-Roels. 1998. Response to hepatitis B vaccine: multiple HLA genes are involved. Tissue Antigens 51:593-604.
8. Diminsky, D., N. Moav, M. Gorecki, and Y. Barenholz. 1999. Physical, chemical and immunological stability of CHO-derived hepatitis B surface antigen (HBsAg) particles. Vaccine 18:3-17.
9. Gavilanes, F., J. Gomez-Gutierrez, M. Aracil, J. M. Gonzalez-Ros, J. A. Ferragut, E. Guerrero, and D. L. Peterson. 1990. Hepatitis B surface antigen. Role of lipids in maintaining the structural and antigenic properties of protein components. Biochem. J. 265:857-864.
10. Godkin, A., M. Davenport, and A. V. Hill. 2005. Molecular analysis of HLA class II associations with hepatitis B virus clearance and vaccine nonresponsiveness. Hepatology 41:1383-1390.
11. Gomez-Gutierrez, J., I. Rodriguez-Crespo, D. L. Peterson, and F. Gavilanes. 1995. Antigenicity of hepatitis B surface antigen proteins reconstituted with phospholipids. Biochim. Biophys. Acta 1233:205-212.
12. Goudeau, A., F. Barin, P. Coursaget, P. Sizaret, M. André, and P. Maupas. 1978. Effect of deoxycholate on ultrastructure and antigenicity of hepatitis B surface antigen (HBsAg), p. 707. In G. N. Vyas, S. N. Cohen, and R. Schmid (ed.), Viral hepatitis. The Franklin Institute Press, Philadelphia, Pa.
13. Heukeshoven, J., and R. Dernick. 1988. Improved silver staining procedure for fast staining in PhastSystem Development Unit. I. Staining of sodium dodecyl sulfate gels. Electrophoresis 9:28-32.
14. Hollingcr, B. L., E. Adam, D. Heiberg, and L. J. Melnick. 1982. Responses to hepatitis B vaccine in a young adult population. Franklin Institute Press, Philadelphia, Pa.
15. Howard, C. R., H. J. Stirk, S. E. Brown, and M. W. Steward. 1988. Towards the development of synthetic hepatitis B vaccines, p. 1094-1101. In A. J. Zuckerman (ed.), Viral hepatitis and liver disease. Liss, New York, N.Y.
16. Kim, C. Y., and D. M. Bissell. 1971. Stability of the lipid and protein of hepatitis-associated (Australia) antigen. J. Infect. Dis. 123:470-476.
17. Kruskall, M. S., C. A. Alper, Z. Awdeh, E. J. Yunis, and D. Marcus-Bagley. 1992. The immune response to hepatitis B vaccine in humans: inheritance patterns in families. J. Exp. Med. 175:495-502.
18. Leroux-Roels, G., I. Desombere, L. Cobbaut, M. A. Petit, P. Desmons, P. Hauser, A. Delem, D. De Grave, and A. Safary. 1997. Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences. 2. Immunogenicity in poor responders to hepatitis B vaccines. Vaccine 15:1732-1736.
19. Leroux-Roels, G., I. Desombere, G. De Tollenaere, M. A. Petit, P. Desmons, P. Hauser, A. Delem, D. De Grave, and A. Safary. 1997. Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences. 1. Safety and immunogenicity in young, healthy adults. Vaccine 15:1724-1731.
20. Leroux-Roels, G., E. Van Hecke, W. Michielsen, P. Voet, P. Hauser, and J. Petre. 1994. Correlation between in vivo humoral and in vitro cellular immune responses following immunization with hepatitis B surface antigen (HBsAg) vaccines. Vaccine 12:812-818.
21. McDermott, A. B., J. N. Zuckerman, C. A. Sabin, S. G. Marsh, and J. A. Madrigal. 1997. Contribution of human leukocyte antigens to the antibody response to hepatitis B vaccination. Tissue Antigens 50:8-14.
22. McMahon, B. J., D. L. Bruden, K. M. Petersen, L. R. Bulkow, A. J. Parkinson, O. Nainan, M. Khristova, C. Zanis, H. Peters, and H. S. Margolis. 2005. Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up. Ann. Intern. Med. 142:333-341.
23. Milich, D. R., and F. V. Chisari. 1982. Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). I. H-2 restriction of the murine humoral immune response to the a and d determinants of HBsAg. J. Immunol. 129:320-325.
24. Milich, D. R., and G. G. Leroux-Roels. 2003. Immunogenetics of the response to HBsAg vaccination. Autoimmun. Rev. 2:248-257.
25. Milich, D. R., G. G. Leroux-Roels, R. E. Louie, and F. V. Chisari. 1984. Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions. J. Exp. Med. 159:41-56.
26. Peterson, D. L. 1981. Isolation and characterization of the major protein and glycoprotein of hepatitis B surface antigen. J. Biol. Chem. 256:6975-6983.
27. Petre, J., F. Van Wijnendaele, B. De Neys, K. Conrath, O. Van Opstal, P. Hauser, T. Rutgers, T. Cabezon, C. Capiau, N. Harford, et al. 1987. Development of a hepatitis B vaccine from transformed yeast cells. Postgrad. Med. J. 63(Suppl. 2):73-81.
28. Prange, R., and R. E. Streeck. 1995. Novel transmembrane topology of the hepatitis B virus envelope proteins. EMBO J. 14:247-256.
29. Rehermann, B., and M. Nascimbeni. 2005. Immunology of hepatitis B virus and hepatitis C virus infection. Nat. Rev. Immunol. 5:215-229.
30. Skelly, J., C. R. Howard, and A. J. Zuckerman. 1981. Hepatitis B polypeptide vaccine preparation in micelle form. Nature 290:51-54.
31. Sonveaux, N., K. Conrath, C. Capiau, R. Brasseur, E. Goormaghtigh, and J. M. Ruysschaert. 1994. The topology of the S protein in the yeast-derived hepatitis B surface antigen particles. J. Biol. Chem. 269:25637-25645.
32. Sonveaux, N., J. M. Ruysschaert, and R. Brasseur. 1995. Proposition of a three-dimensional representation of the constitutive protein of the hepatitis B surface antigen particles. J. Protein Chem. 14:477-486.
33. Sonveaux, N., D. Thines, and J. M. Ruysschaert. 1995. Characterization of the HBsAg particle lipid membrane. Res. Virol. 146:43-51.
34. Stirk, H. J, J. M. Thornton, and C. R. Howard. 1992. A topological model for hepatitis B surface antigen. Intervirology 33:148-158.
35. Van der Meeren, P., W. Van Criekinge, J. Vanderdeelen, and L. Baert. 1994. Phospholipid composition of r-DNA hepatitis B surface antigens. Int. J. Pharm. 106:89-92.
36. West, D. J., and G. B. Calandra. 1996. Vaccine induced immunologic memory for hepatitis B surface antigen: implications for policy on booster vaccination. Vaccine 14:1019-1027.