Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons

Journal of Neuroscience

Volumn 26, Issue 12, 2006, Pages 3256-3268

  Soundararajan, Prabakaran ^a   Miles, Gareth B ^a   Rubin, Lee L ^b   Brownstone, Robert M ^a   Rafuse, Victor F ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b CURIS INC   (United States)

Author keywords

Axon guidance; Chemotropic; Development; Lhx3; Motoneuron (motor neuron); Neuromuscular; Regeneration; Sonic hedgehog; Spinal cord; Stem cells; Transcription factor

Indexed keywords

GREEN FLUORESCENT PROTEIN; NEURITE PROMOTING FACTOR; POLYSIALIC ACID; TRANSCRIPTION FACTOR;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL MIGRATION; EMBRYONIC STEM CELL; GENE EXPRESSION; HOMEOBOX; IN VITRO STUDY; MESENCHYME CELL; MOTONEURON; MUSCLE INNERVATION; NEURAL TUBE; NONHUMAN; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE VESICLE;

ACTION POTENTIALS; ANIMALS; BODY PATTERNING; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; CHEMOTACTIC FACTORS; CHICK EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GRAFT SURVIVAL; GREEN FLUORESCENT PROTEINS; GROWTH CONES; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; MOTOR NEURONS; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; PATCH-CLAMP TECHNIQUES; PHENOTYPE; PLURIPOTENT STEM CELLS; SPINAL CORD; STEM CELL TRANSPLANTATION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRETINOIN;

EID: 33645219877     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5537-05.2006     Document Type: Article

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