Effects in Liver

Advances in Pharmacology

Volumn 52, Issue , 2005, Pages 229-234

  Young, Andrew ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; AMYLOID; ANTIDIABETIC AGENT; PRAMLINTIDE;

ANIMAL; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; GLUCONEOGENESIS; HUMAN; LIVER; METABOLISM; REVIEW; SPECIES DIFFERENCE;

AMYLOID; ANIMALS; GLUCONEOGENESIS; HUMANS; HYPOGLYCEMIC AGENTS; LIVER; SPECIES SPECIFICITY;

EID: 33645219871     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(05)52012-X     Document Type: Review

References (33)

1. Betts J.J., Lupien J.R., and Horton E.S. Amylin induces in vivo insulin resistance in rats. Diabetes 40 (1991) 35A
2. Choi S.B., Frontoni S., and Rossetti L. Mechanism by which calcitonin gene-related peptide antagonizes insulin action in vivo. Am. J. Physiol. 260 (1991) E321-E325
3. Fillers W.S., Cohen D.K., and Bell P.A. Amylin sensitivity in isolated hepatocytes. Diabetes 40 (1991) 21A
4. Frontoni S., Choi S.B., Banduch D., and Rossetti L. In vivo insulin resistance induced by amylin primarily through inhibition of insulin-stimulated glycogen synthesis in skeletal muscle. Diabetes 40 (1991) 568-573
5. Gedulin B., Larson E., Young A.A., and Rink T.J. Combined hyperlactemic and hyperglycemic clamps in anesthetized rats with acute pancreatectomy or somatostatin infusion; effects of amylin on endogenous lactate and glucose production. Program and Abstracts, the Endocrine Society, 76th Annual Meeting (1994) 373
6. Holder J.C., Cawthorne M.A., Cooper G.J.S., Coyle P.J., Rink T.J., and Smith S.A. Acute effects of amylin on hepatic and peripheral insulin action in the rat. Diabetologia 34 (1991) A104
7. Koopmans S.J., vanMansfeld A.D.M., Jansz H.S., Krans H.M.J., Radder J.K., Frolich M., deBoer S.F., Kreutter D.K., Andrews G.C., and Maassen J.A. Pancreatic amylinamide induces in vivo hepatic and peripheral insulin resistance in the rat. Diabetes 39 (1990) 101A
8. Koopmans S.J., vanMansfeld A.D.M., Jansz H.S., Krans H.M.J., Radder J.K., Frölich M., deBoer S.F., Kreutter D.K., Andrews G.C., and Maassen J.A. Amylin-induced in vivo insulin resistance in conscious rats: The liver is more sensitive to amylin than peripheral tissues. Diabetologia 34 (1991) 218-224
9. Molina J.M., Cooper G.J.S., and Olefsky J.M. Calcitonin gene-related peptide causes insulin resistance in vivo. Clin. Res. 37 (1989) 456A
10. Molina J.M., Cooper G.J.S., Leighton B., and Olefsky J.M. Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide. Diabetes 39 (1990) 260-265
11. Morishita T., Yamaguchi A., Yamatani T., Nakamura A., Arima N., Yamashita Y., Nakata H., Fujita T., and Chiba T. Effects of islet amyloid polypeptide (amylin) and calcitonin gene-related peptide (CGRP) on glucose metabolism in the rat. Diabet. Res. Clin. Pract. 15 (1992) 63-69
12. Nishimura S., Sanke T., Machida K., Bessho H., Nakai K., Negoro T., Kondo M., and Nanjo K. Effects of islet amyloid polypeptide (IAPP/amylin) on glucose output in perfused rat liver. Diabetes 40 (1991) 242A
13. Nishimura S., Sanke T., Machida K., Bessho H., Hanabusa T., Nakai K., and Nanjo K. Lack of effect of islet amyloid polypeptide on hepatic glucose output in the in situ perfused rat liver. Metabolism 41 (1992) 431-434
14. Nouspikel T., Gjinovci A., Li S.L., and Iynedjian P.B. Unimpaired effect of insulin on glucokinase gene expression in hepatocytes challenged with amylin. FEBS Lett. 301 (1992) 115-118
15. Orskov L., Nyholm B., Hove K., Gravholt C., Moller N., Kolterman O., Alberti K., and Schmitz O. Effects of the amylin analogue pramlintide on the glucose response to a glucagon challenge in IDDM. Diabetologia 40 (1997) A355
16. Orskov L., Nyholm B., Hove K.Y., Gravholt C.H., Moller O., Kolterman O., Alberti K.G.M.M., and Schmitz O. Effects of the amylin analogue pramlintide on the glucose response to a glucagon challenge in IDDM. Diabetes 46 (1997) 155A
17. Orskov L., Nyholm B., Hove K.Y., Gravholt C.H., Moller N., and Schmitz O. Effects of the amylin analogue pramlintide on hepatic glucagon responses and intermediary metabolism in type 1 diabetic subjects. Diabet. Med. 16 (1999) 867-874
18. Pittner R.A. Lack of effect of calcitonin gene-related peptide and amylin on major markers of glucose metabolism in hepatocytes. Eur. J. Pharmacol. 325 (1997) 189-197
19. Pittner R., Wolfe-Lopez D., Beaumont K., and Rink T. Lack of effect of amylin on major markers of glycogenolysis and gluconeogenesis on isolated rat hepatocytes. Diabetes 45 (1996) 235A
20. Rink T., and Gedulin B. Lactate clamp: A new technique for studying carbohydrate metabolism in vivo. Diabetes 42 suppl. 1 (1993) 245A
21. Rink T.J., Larson E., Young A.A., and Gedulin B. Effects of amylin on lactate metabolism in the rat: Studies using hyperactemic/hyperglycemic clamps. Diabetologia 37 (1994) A117
22. Roden M., Kothbauer I., Vierhapper H., and Waldhäusl W. Failure of amylin to affect insulin sensitivity in the isolated perfused rat liver. Diabetologia 33 (1990) A39
23. Roden M., Fürnsinn C., Vierhapper H., and Waldhäusl W. Amylin does not cause hepatic insulin-resistance in the perfused rat liver. Diabetes 40 (1991) 36A
24. Roden M., Liener K., Furnsinn C., Nowotny P., Hollenstein U., Vierhapper H., and Waldhausl W. Effects of islet amyloid polypeptide on hepatic insulin resistance and glucose production in the isolated perfused rat liver. Diabetologia 35 (1992) 116-120
25. Stephens T.W., and Hermeling R.N. Liver amylin/CGRP receptors are present only in non-parenchymal cells and do not directly regulate liver glucose metabolism in the rat. Diabetes 40 (1991) 300A
26. Stephens T.W., Heath W.F., and Hermeling R.N. Presence of liver CGRP/amylin receptors in only nonparenchymal cells and absence of direct regulation of rat liver glucose metabolism by CGRP/amylin. Diabetes 40 (1991) 395-400
27. Wolfe R.R. "Tracers in Metabolic Research: Radioisotope and Stable Isotope/Mass Spectometry Methods." (1984), A. R. Liss, New York
28. Young A.A., Crocker L.B., Wolfe-Lopez D., and Cooper G.J.S. Daily amylin replacement reverses hepatic glycogen depletion in insulin-treated streptozotocin diabetic rats. FEBS Lett. 287 (1991) 203-205
29. Young A.A., Wang M.W., and Cooper G.J.S. Amylin injection causes elevated plasma lactate and glucose in the rat. FEBS Lett. 291 (1991) 101-104
30. Young A.A., Wang M.-W., Rink T.J., and Cooper G.J.S. Effects of intravenous injections of amylin in the fasted, anaesthetized rat. J. Physiol. 438 (1991) 250P
31. Young A.A., Carlo P., Smith P., Wolfe-Lopez D., Pittner R., Wang M.W., and Rink T. Evidence for release of free glucose from muscle during amylin-induced glycogenolysis in rats. FEBS Lett. 334 (1993) 317-321
32. Young A.A., Cooper G.J.S., Carlo P., Rink T.J., and Wang M.W. Response to intravenous injections of amylin and glucagon in fasted, fed, and hypoglycemic rats. Am. J. Physiol. 264 (1993) E943-E950
33. Young D.A., Deems R.O., Deacon R.W., McIntosh R.H., and Foley J.E. Effects of amylin on glucose metabolism and glycogenolysis in vivo and in vitro. Am. J. Physiol. 259 (1990) E457-E461