Nonspecific binding removal from protein microarrays using thickness shear mode resonators

IEEE Sensors Journal

Volumn 6, Issue 2, 2006, Pages 254-261

  Meyer, Grant D ^b   Morán Mirabal, José M ^b   Branch, Darren W ^c,d,e   Craighead, Harold G ^a  

^a IEEE   (United States)

^b School of Chemical and Molecular Engineering   (United States)

^c SANDIA NATIONAL LABORATORIES   (United States)

^d SANDIA NATIONAL LABORATORIES   (United States)

^e Microsensor Science and Technology Department   (United States)

Author keywords

Nonspecific binding; Protein microarray; Quartz crystal resonator; Ultrasonic

Indexed keywords

NONSPECIFIC BINDING; PROTEIN MICROARRAYS; QUARTZ CRYSTAL RESONATOR; SPECIFICITY;

ANTIBODIES; ATOMIC FORCE MICROSCOPY; BIOASSAY; DESORPTION; FLUORESCENCE; PROTEINS; QUARTZ; RESONATORS; SENSITIVITY ANALYSIS; ULTRASONIC WAVES;

BIOSENSORS;

EID: 33645141797     PISSN: 1530437X     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSEN.2006.870172     Document Type: Article

References (8)

1. A. W. Liew, H. Yan, and M. Yang, "Robust adaptive spot segmentation of DNA microarray images," Pattern Recognit., vol. 36, pp. 1251-1254, 2003.
2. Y. Chen et al., "Ratio statistics of gene expression levels and applications to microarray data analysis," Bioinformatics, vol. 18, no. 9, pp. 1207-1215, 2002.
3. L. Jespers, O. Schon, K. Famm, and G. Winter, "Aggregation resistant domain antibodies selected on phage by heat denaturation," Nature Biotechnol., vol. 22, no. 9, pp. 1161-1165, Sep. 2004.
4. L. McKenna, MI. Newton, G. McHale, R. Lockland, and J. Schroeder, "Compressional acousit wave generation in microdroplets of water in contact with quartz crystal resonators," J. Appl. Phys., vol. 89, no. 1, pp. 676-680.
5. B. Ilic and H. G. Craighead, "Topographical patterning of chemically sensitive biological materials using a polymer based dry lift off," Biomed. Microdevices, vol. 2, no. 4, pp. 317-322, 2000.
6. B. Åkerström and L. Björck, "A physicochemical study of protein G, a molecule with unique immunoglobulin G-binding properties," J. Biol. Chem., vol. 261, no. 22, pp. 10240-10247, Aug. 1986.
7. N. Otsu, "A threshold selection method from gray level histograms," IEEE Trans. Syst., Man, Cybern., vol. SMC-9, no. 1, pp. 62-66, Jan. 1979.
8. R. Vijayendran and D. Leckband, "A quantitative assessment of heterogeneity for surface-immobilized proteins," Anal. Chem., vol. 73, pp. 471-480, 2001.