Endocrine disrupting chemical atrazine causes degranulation through Gq/11 protein-coupled neurosteroid receptor in mast cells

Toxicological Sciences

Volumn 90, Issue 2, 2006, Pages 362-368

  Mizota, Kaori ^a   Ueda, Hiroshi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Degranulation; Endocrine disrupting chemical; Extravasation; Mast cell; Neurosteroid

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ANTISENSE OLIGODEOXYNUCLEOTIDE; ATRAZINE; BETA N ACETYLHEXOSAMINIDASE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; DIPHENHYDRAMINE; ENDOCRINE DISRUPTOR; HERBICIDE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; LANTHANUM CHLORIDE; LIPOCORTIN 5; PERTUSSIS TOXIN; PHOSPHATIDYLSERINE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PROGESTERONE; PROGESTERONE RECEPTOR; STEROID RECEPTOR; XESTOSPONGIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME RELEASE; EXTRAVASATION; FOOT PAD; IN VITRO STUDY; INFLAMMATION; MALE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PAIN; PROTEIN BINDING; RECEPTOR INTRINSIC ACTIVITY; STATISTICAL ANALYSIS;

ANIMALS; ATRAZINE; BETA-N-ACETYLHEXOSAMINIDASE; CELL DEGRANULATION; CELL LINE; ENDOCRINE DISRUPTORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HERBICIDES; MALE; MAST CELLS; MICE; RECEPTORS, G-PROTEIN-COUPLED;

ALEXA; ANIMALIA;

EID: 33645125051     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj087     Document Type: Article

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