General microwave-assisted protocols for the expedient synthesis of furo[3,2-c]chromen-4-ones

Chemistry Letters

Volumn 35, Issue 1, 2006, Pages 118-119

  Wu, Jie ^a,b  

^a VivoQuest Inc   (United States)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33645124216     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2006.118     Document Type: Article

References (28)

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28. General procedure: 4-hydroxycoumarin (0.25 mmol), aldehyde (0.25 mmol), and isocyanide (0.25 mmol) in DMF (3.0 mL) were reacted under microwave irradiation in a sealed vial (300 W and 150 °C) for 5 min (automated microwave synthesizer, Initiator Eight™, Biotage). After washed with water (10 mL) and extracted with ethyl acetate (10 mL), the solvent was evaporated. The resulting residue was purified via preparative TLC to afford the desired product.