Platelet function of newborns as tested by cone and plate(let) analyzer correlates with gestational age

Acta Haematologica

Volumn 115, Issue 3-4, 2006, Pages 152-156

  Levy Shraga, Y ^a   Maayan Metzger, A ^a   Lubetsky, A ^b,c   Shenkman, B ^b,c   Kuint, J ^a   Martinowitz, U ^b,c   Kenet, G ^b,c  

^a Edmond and Lily Safra Children's Hospital   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Cone and plate(let) analyzer; Platelet function

Indexed keywords

POLYSTYRENE;

ANALYZER; ARTICLE; BIRTH; CONTROLLED STUDY; CORRELATION ANALYSIS; GESTATIONAL AGE; HUMAN; HUMAN CELL; INFANT; LABORATORY; MATERNAL HYPERTENSION; MOTHER; NEWBORN; PERINATAL PERIOD; PREMATURITY; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; UMBILICAL CORD BLOOD;

ADULT; BLOOD PLATELETS; FEMALE; GESTATIONAL AGE; HUMANS; HYPERTENSION; INFANT, NEWBORN; INFANT, PREMATURE; MALE; PLATELET ADHESIVENESS; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR;

EID: 33645118805     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090928     Document Type: Article

References (35)

1. Nathan D, Orkin S: Nathan and Oski's Hematology of Infancy and Childhood, ed 6. Philadelphia, WB Saunders, 2003.
2. Andrew M, Paes B, Milner M: Development of human coagulation system in the full term infant. Blood 1987;70:165-172.
3. Andrew M, Paes B, Milner M: Development of human coagulation system in healthy premature infant. Blood 1988;72:1651-1657.
4. Aballi AJ, de Lamerens S: Coagulation changes in the neonatal period and in early infancy. Pediatr Clin North Am 1962;9:785-817.
5. Andrew M, Kelton J: Neonatal thrombocytopenia. Clin Perinatal 1984;11:359-391.
6. Arad ID, Alpan G, Sznajderrman SD, Eldor A: The mean platelet volume in the neonatal period. Am J Perinatal 1986;3:1-3.
7. Mankin P, Marngos J, Akhand M, Saving KL: Impaired platelet dense granules release in neonate. J Pediatr Hematol Oncol 2000;22:143-147.
8. Rajasekhar D, Kestin A, Bednarek F: Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood. Thromb Haemost 1994;72:957-963.
9. Rajasekhar D, Barnard M, Francis J, Bednarek F: Platelet hyporeactivity in very low birth weight neonates. Thromb Haemost 1997;77: 1002-1007.
10. Simak J, Holada K, Janota J, Stranak Z: Surface expression of major membrane glycoproteins on resting and TRAP-activated neonatal platelets. Pediatr Res 1999;46 445-449.
11. Hezard N, Potron G, Schlegel N, Amory C, Leroux B, Nguyen P: Unexpected persistence of platelet hyporeactivity beyond the neonatal period: a flow cytometric study in neonates, infants and older children. Thromb Haemost 2003;90:116-123.
12. Varon D, Dardik R, Shenkman B, Kotev-Emeth S, Farzame N, Tamarin I, Savion N: A new method for quantitative analysis of whole blood platelet interaction with extracellular matrix under flow conditions. Thromb Res 1997;85:283-294.
13. Knobler H, Savion N, Shenkman B, Kotev-Emeth S, Varon D: Shear induced platelet adhesion and aggregation on subendothelium are increased in diabetic patients. Thromb Res 1998;90:181-190.
14. Kennet G, Lubetsky A, Shenkman B, Tamarin I, Dardik R, Rechavi A, Barzilai A, Martinowitz U, Savion N, Varon D: Cone and platelet analyzer (CPA): a new test for prediction of bleeding among thrombocytopenic patients. Br J Haematol 1998;101:255-259.
15. Shenkman B, Rubinstein E, Tamarin I, Dardik R, Savion N, Varon D: Activated platelets mediate Staphylococcus aureus deposition on subendothelial extracellular matrix: the role of glycoprotein Ib. Platelets 1999;10:36-44.
16. Dardik R, Kaufmann Y, Savion N, Rosenberg N, Shenkman B, Varon D: Platelets mediate tumor cell adhesion to the subendothelium under flow conditions: involvement of platelet GPIIbIIIa and tumor cell integrins. Int J Cancer 1997;70:201-207.
17. Shenkman B, Linder N, Savion N, Dardik R, Kennet G, German B, Varon D: Increased neonatal platelet deposition on subendothelium under flow conditions: the role of plasma von Willebrand factor. Pediatr Res 1999;45:270-275.
18. Linder N, Shenkman B, Levin E, Sirota L, Tamarin I, Dardik R, Lubin D, Savion N, Varon D: Deposition of whole blood platelet on extracellular matrix under flow conditions in preterm infants. Arch Dis Child 2002;86:127-130.
19. Finkelstein Y, Shenkman B, Sirota L, Vishne TH, Dardik R, Varon D, Linder N: Whole blood platelet deposition on extracellular matrix under flow conditions in preterm neonatal sepsis. Eur J Pediatr 2002;161:270-274.
20. Shenkman B, Savion N, Tamarin I, Dardik R, Varon D: Testing of platelet deposition on polystyrene surface under flow conditions by cone and platelet analyzer: the role of platelet activation, fibrinogen and von Willebrand factor. Thromb Res 2000;99:353-361.
21. Kuhne T, Ryan G, Blanchette V, Kuhne T, Ryan G, Blanchette V, Semple JW, Hornstein A, Mody M, Chang W, McWhirter L, Freedman J: Platelet surface glycoproteins in healthy and preeclamptic mothers and their newborn infants. Pediatr Res 1996;40:876-880.
22. Sitaru AG, Holzhauer S, Speer GP, Singer D, Obergfell A, Waller U, Grossman R: Neonatal platelets from cord blood and peripheral blood. Platelets 2005;16:203-210.
23. Corby DG, O'Barr TP: Decreased alpha-adrenergic receptors in newborn platelets: cause of abnormal response to epinephrine. Dev Pharmacol Ther 1981;2:215-225.
24. Israels SJ, Odaibo FS, Robertson C, McMillan EM, McNicol A: Deficient thromboxane synthesis and response in platelets from premature infants. Pediatr Res 1997;41:218-223.
25. Israels SJ, Cheang T, Robertson C, McMillanWard EM, McNicol A: Impaired signal transduction in neonatal platelets. Pediatr Res 1999;45:687-691.
26. Gelman B, Setty BNY, Chen D, Amin-Hanjani S, Stuart MJ: Impaired mobilization of intracellular calcium in neonatal platelets. Pediatr Res 1996;39:692-696.
27. Katz JA, Moake JL, McPherson PD, Weinstein MJ, Moise KJ, Carpenter RJ, Sala DJ: Relationship between human development and disappearance of unusually large von Willebrand factor multimers from plasma. Blood 1989;73:1851-1858.
28. Weinstein MJ, Blanchard R, Moake JL, Vosburgh E, Moise K: Fetal and neonatal von Willebrand factor (VWF) is unusually large and similar to the VWF in patients with thrombotic thrombocytopenic purpura. Br J Haematol 1989;72:68-72.
29. Aronis S, Platokouki H, Photopoulos S, Adamtziki E, Xanthou M: Indications of coagulation and/or fibrinolytic system activation in healthy and sick very low birth weight infants. Biol Neonate 1998;74:337-344.
30. Yoffe G, Buchanan GR: Intracranial hemorrhage in newborn and young infants with hemophilia. J Pediatr 1988;113:333.
31. Abbondanzo SL, Gootenbeg JE, Lofts R, McPherson R: Intracranial hemorrhage in congenital deficiency of FXIII. Am J Pediatr Hematol Oncol 1988;10:65-68.
32. Struwe FE: Intracranial hemorrhage and occlusive hydrocephalus in hereditary bleeding disorders. Dev Med Child Neurol 1970;12:165.
33. Pet J, Hiltunen L, Felman V: Increased risk of intraventricular hemorrhage in preterm infants with thrombophilia. Pediatr Res 2001;49:643-646.
34. Riikonen R, Kekomaki R: Resistance to activated protein C in childhood hydrocephalus. Thromb Haemost 1998;79:1059-1060.
35. Kenet G, Maayan-Metzger A, Rosenberg N, Sela BA, Mazkereth R, Ifrah A, Kuint J: Thrombophilia does not increase risk for neonatal complications in preterm infants. Thromb Haemost 2003;90:823-828.