Arterial ischemic stroke and cerebral venous thrombosis in children: A 12-year Argentinean registry

Acta Haematologica

Volumn 115, Issue 3-4, 2006, Pages 180-185

  Bonduel, Mariana ^a   Sciuccati, Gabriela ^a   Hepner, Mirta ^a   Pieroni, Graciela ^a   Torres, Aurora Feliú ^a   Frontroth, Juan Pablo ^a   Tenembaum, Silvia ^a  

^a HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

Author keywords

Acenocoumarol; Children; Stroke; Thrombophilia

Indexed keywords

ACENOCOUMAROL; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN; PROTHROMBIN A;

ADOLESCENT; ARGENTINA; ARTICLE; BRAIN CORTEX; CHILD; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MORTALITY; PEDIATRIC HOSPITAL; PERIPHERAL ISCHEMIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; REGISTER; VEIN THROMBOSIS;

ADOLESCENT; ARGENTINA; BRAIN ISCHEMIA; CEREBRAL INFARCTION; CHILD; CHILD, PRESCHOOL; FACTOR V; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INFANT; INTRACRANIAL THROMBOSIS; MALE; POINT MUTATION; REGISTRIES; RETROSPECTIVE STUDIES;

EID: 33645111224     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090932     Document Type: Article

References (28)

1. Andrew M, Monagle PT, Brooker L: Stroke; in Andrew M, Monagle PT, Brooker L (eds): Thromboembolic Complications during Infancy and Childhood. London, Decker, 2000, pp 47-110.
2. Schoenberg BS, Mellinger JF, Schoenberg DF: Cerebrovascular disease in infants and children: a study of incidence, clinical features, and survival. Neurology 1978;28:763-768.
3. deVeber G, Andrew M, Adams C, Bjornson B, Booth F, Buckley DJ, Camfield CS, David M, Humphreys P, Langevin P, MacDonald EA, Meaney B, Shevell M, Sinclair DB, Yager J, Gillett J: Cerebral sinovenous thrombosis in children. N Engl J Med 2001;345:417-423.
4. Heller C, Heinecke A, Junker R, Knöfler R, Kosch A, Kurnik K, Schobess R, von Eckardstein A, Sträter R, Zieger B, Nowak-Göttl U; Childhood Stroke Study Group: Cerebral venous thrombosis in children. A multifactorial origin. Circulation 2003;108:1362-1367.
5. Bonduel M, Sciuccati G, Hepner M, Torres AF, Pieroni G, Frontroth JP: Prethrombotic disorders in children with arterial ischemic stroke and sinovenous thrombosis. Arch Neurol 1999;56:967-971.
6. Bonduel M, Sciuccati G, Hepner M, Pieroni G, Torres AF, Mardaraz C, Frontroth JP: Factor V Leiden and prothrombin gene G20210A mutation in children with cerebral thromboembolism. Am J Hematol 2003;73:81-86.
7. deVeber G, Monagle P, Chan A, MacGregor D, Curtis R, Lee S, Vegh P, Adams M, Marzinotto V, Leaker M, Massicotte P, Lillicrap D, Andrew M: Prothrombotic disorders in infants and children with cerebral thromboembolism. Arch Neurol 1998;55:1539-1543.
8. Nowak-Göttl U, Sträter R, Heinecke A, Junker R, Koch HG, Schuierer G, von Eckardstein A: Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in children. Blood 1999;94:3678-3682.
9. Ganesan V, McShane MA, Liesner R, Cookson J, Hann I, Kirkham FJ: Inherited prothrombotic states and ischaemic stroke in childhood. J Neurol Neurosurg Psychiatry 1998;65:508-511.
10. Ganesan V, Prengler M, McShane MA, Wade AM, Kirkham FJ: Investigation of risk factors in children with arterial ischemic stroke. Ann Neurol 2003;53:167-173.
11. Kenet G, Sadetzki S, Murad H, Martinowitz U, Rosenberg N, Gitel S, Rechavi G, Inbal A: Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children. Stroke 2000;31:1283-1288.
12. Kenet G, Waldman D, Lubetsky A, Kornbrut N, Khalil A, Koren A, Wolach B, Fattal A, Kapelushnik J, Tamary H, Yacobovitch J, Raveh E, Revel-Vilk S, Toren A, Brenner B: Paediatric cerebral sinus vein thrombosis. A multi-center, case-controlled study. Thromb Haemost 2004;92:713-718.
13. Hézard N, Cornillet-Lefebvre P, Gillot L, Potron L, Nguyen P: Multiplex ASA PCR for a simultaneous determination of factor V Leiden gene, G→A 20210 prothrombin gene and C→T 677 MTHFR gene mutations. Thromb Haemost 1998;79:1054-1055.
14. Laurell CB: Electroimmuno assay Scand J Clin Lab Invest 1972;29:21-37.
15. Comp PC, Nixon RR, Cooper MR, Esmon CT: Familial protein S deficiency is associated with thrombosis. J Clin Invest 1984;74:2082-2088.
16. Brandt JT, Triplett DA, Alvin B, Scharrer I: Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardization Committee of the ISTH. Thromb Haemost 1995;74:1185-1190.
17. Triplett DA, Brandt JT, Kaczor D, Schaeffer J: Laboratory diagnosis of lupus inhibitors: a comparison of the tissue thromboplastin inhibition procedure with a new platelet neutralization procedure. Am J Clin Pathol 1983;79:678-682.
18. Harris EN, Gharavi AE, Patel SP, Hughes GR: Evaluation of the anticardiolipin antibody test: report of an international workshop held 4 April 1986. Clin Exp Immunol 1987;68:215-222.
19. Harris EN, Khamashta MA, Hughes GRV: Antiphospholipid antibody syndrome; in Mc Carthy DJ, Koopman WJ (eds): Arthritis and Allied Conditions, ed 12. Philadelphia, Lea & Febiger, 1991, pp 1201-1212.
20. Amitage P, Berry G: Statistical methods in medical research; in Further Analysis of Categorical Data. Oxford, Blackwell, 1994.
21. Rothman K, Greenland S: Case control studies; in Rothman K, Greenland S (eds): Modern Epidemiology, ed 2. Philadelphia, Lippincott-Raven, 1998, pp 93-114.
22. Bonduel M, Sciuccati G, Hepner M, Feliú Torres A, Sackmann Muriel F: Thrombosis in children with acute lymphoblastic leukaemia (ALL) and L-asparaginase (ASP) therapy (abstract). Blood 1997;90:3756.
23. McColl MD, Chalmers EA, Thomas A, Sproul A, Healey C, Rafferty I, McWilliam R, Eunson P: Factor V Leiden, prothrombin 20210G→A and the MTHFR C677T mutations in childhood stroke. Thromb Haemost 1999;81:690-694.
24. Riikonen RS, Santavuori P: Hereditary and acquired risk factors for childhood stroke. Neuropediatrics 1994;25:227.
25. Riikonen RS, Vahtera EM, Kekomäki RM: Physiological anticoagulants and activated protein C resistance in childhood stroke. Acta Paediatr 1996;85:242-244.
26. Becker S, Heller C, Gropp F, Scharrer I, Kreuz W: Thrombophilic disorders in children with cerebral infarction. Lancet 1998;352:1756-1757.
27. Monagle P, Chan A, Massicotte P, Chalmers E, Michelson AD: Antithrombotic therapy in children: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004;126:645S-687S.
28. Bonduel M, Sciuccati G, Hepner M, Torres AF, Pieroni G, Frontroth JP, Serviddio RM: Acenocoumarol therapy in pediatric patients. J Thromb Haemost 2003;1:740-743.