Anti-PCNA autoantibodies preferentially recognize C-terminal of PCNA in patients with chronic hepatitis B virus infection

Clinical and Experimental Immunology

Volumn 144, Issue 1, 2006, Pages 110-116

  Hsu, T C ^a   Tsay, G J ^a,b   Chen, T Y ^b   Liu, Y C ^c   Tzang, B S ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Antigenic regions; Autoantibody; Hepatitis B virus (HBV); Hepatitis C virus (HCV); Proliferating cell nuclear antigen (PCNA)

Indexed keywords

AUTOANTIBODY; CYCLINE ANTIBODY; PROTEIN ANTIBODY; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIBODY DETECTION; ANTIGEN BINDING; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONSTRUCT; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN PURIFICATION; SYSTEMIC LUPUS ERYTHEMATOSUS; WILD TYPE;

ABSORPTION; AUTOANTIBODIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HEPATITIS B ANTIBODIES; HEPATITIS B, CHRONIC; HEPATITIS C ANTIBODIES; HEPATITIS C, CHRONIC; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LUPUS ERYTHEMATOSUS, SYSTEMIC; MUTATION; PROLIFERATING CELL NUCLEAR ANTIGEN; RECOMBINANT PROTEINS;

EID: 33645107578     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2006.03046.x     Document Type: Article

References (32)

1. Hansen KE Arnason J Bridges AJ Autoantibodies and common viral illnesses Semin Arthritis Rheum 1998 27 263 71
2. Buskila D Sikuler E Shoenfeld Y Hepatitis C virus, autoimmunity and rheumatic disease Lupus 1997 6 685 9
3. Schattner A Rager-Zisman B Virus-induced autoimmunity Rev Inf Dis 1990 12 204 21
4. Panasiuk A Autoantibodies in chronic liver diseases Rocz Akad Med Bialymst 2001 46 106 12
5. Abu-Shakra M El-Sana S Margalith M Sikuler E Neumann L Buskila D Hepatitis B and C viruses serology in patients with SLE Lupus 1997 6 543 4
6. Inman R Rheumatic manifestations of hepatitis B virus infection Semin Arthritis Rheum 1982 11 406 20
7. Prieto J Yuste JR Beloqui O Civeira MP Riezu JI Augirre B Sangro B Anticardiolipin antibodies in chronic hepatitis C. implication of hepatitis C virus as the cause of the antiphospholipid syndrome Hepatology 1996 23 199 204
8. Sung JL Prevention of hepatitis B and C virus infection for prevention of cirrhosis and hepatocellular carcinoma J Gastroenterol Hepatol 1997 12 S370 6
9. Hsu HY Chang MH Chen DS et al. 1984: baseline seroepidemiology of hepatitis B virus infection in children in Taipei. A study just before the mass hepatitis B viral vaccination program in Taiwan J Med Virol 1986 18 301 7
10. Sun CA Chen HC Lu CF et al. Transmission of hepatitis C virus in Taiwan: prevalence and risk factors based on a nationwide survey J Med Virol 1999 59 290 6
11. Miyachi K Fritzler MJ Tan EM Autoantibody to a nuclear antigen in proliferating cells J Immunol 1978 121 2228 34
12. Takasaki Y Fishwild D Tan EM Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera J Exp Med 1984 159 981 92
13. Tan EM Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology Adv Immunol 1989 44 93 151
14. Yeo JP Toh BH Cell cycle-associated autoantibodies: markers for autoimmunity and probes for molecular cell biology Autoimmunity 1994 18 291 300
15. Kurki P Vanderlaan M Dolbeare F Gray J Tan EM Expression of proliferating cell nuclear antigen (PCNA/cyclin) during the cell cycle Exp Cell Res 1986 166 209 19
16. Shivji KK Kenny MK Wood RD Proliferating cell nuclear antigen is required for DNA excision repair Cell 1992 69 367 74
17. Krishna TS Kong XP Gary S Burgers PM Kuriyan J Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA Cell 1994 79 1233 43
18. Fritzler MJ McCarty GA Ryan JP Kinsella TD Clinical features of patients with antibodies directed against proliferating cell nuclear antigen Arthritis Rheum 1983 26 140 5
19. Ohata N Clinical significance of antibodies to proliferating cell nuclear antigen (PCNA) Ryumachi 1987 27 79 87
20. Murashima A Takasaki Y Ohgaki M Hashimoto H Shirai T Hirose S Activated peripheral blood mononuclear cells detected by murine monoclonal antibodies to proliferating cell nuclear antigen in active lupus patients J Clin Immuno 1990 10 28 37
21. Ogata K Ogata Y Takasaki Y Tan EM Epitopes on proliferating cell nuclear antigen recognized by human lupus autoantibody and murine monoclonal antibody J Immunol 1987 139 2943 6
22. Huff JP Roos G Peebles CL Houghten R Sullivan KF Tan EM Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products J Immunol 1990 172 419 29
23. Kogure T Takasaki Y Takeuchi K et al. Autoimmune responses to proliferating cell nuclear antigen multiprotein complexes involved in cell proliferation are strongly associated with their structure and biologic function in patients with systemic lupus erythematosus Arthritis Rheum 2002 46 2946 56
24. Tsai WM Roos G Hugli TE Tan EM Influences of free thiol groups on autoantibody-defined epitopes of proliferating cell nuclear antigen J Immunol 1992 149 2227 33
25. Brand SR Bernstein RM Mathews MB Autoreactive epitope profiles of the proliferating cell nuclear antigen define two classes of autoantibodies J Immunol 1994 153 3070 8
26. Tzang BS Chen TY Hsu TC Liu YC Tsay GJ Presentation of autoantibody to proliferating cell nuclear antigen in patients with chronic hepatitis B and C virus infection Ann Rheum Dis 1999 58 630 4
27. Jonsson ZO Podust VN Podust LM Hubscher U Tyrosine114 is essential for the trimeric structure and functional activities of human proliferating cell nuclear antigen EMBO J 1995 14 5745 51
28. Tan EM Cohen AS Fries JF et al. The revised criteria for the classification of systemic lupus erythematosus Arthritis Rheum 1982 25 1271 7
29. Rubin RL Joslin FG Tan EM An improved ELISA for anti-native DNA by elimination of interference by antihistone antibodies J Immunol Meth 1983 63 359 66
30. Sambrook J Fritsch E Maniatis T Molecular cloning Detection and Analysis of Proteins Expressed from Cloned Genes, Molecular Cloning Vol. 3 Cold Spring Habor Cold Spring Habor Press 1989 18.47 18 75
31. Bootsma H Spronk PE Borg EJ Hummel EJ de Boer G Limburg PC Kallenberg CG The predictive value of fluctuations in IgM and IgG class anti-dsDNA antibodies for relapses in systemic lupus erythematosus. A prospective long term observation Ann Rheum Dis 1997 56 661 6
32. Colaco CB Male DK Anti-phoshpholipid antibodies in syphilis and athrombotic subset of SLE. distinect profiles of epitopes specificity Clin Exp Immunol 1985 59 449 56