A trial of fresh autologous whole blood to treat dilutional coagulopathy following cardiopulmonary bypass in infants

Paediatric Anaesthesia

Volumn 16, Issue 4, 2006, Pages 429-435

  Friesen, Robert H ^a,c   Perryman, Kathy M ^b   Weigers, Kim R ^a   Mitchell, Max B ^a   Friesen, Richard M ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b CHILDREN S MERCY HOSPITAL   (United States)

^c CHILDREN S HOSPITAL   (United States)

Author keywords

Acute normovolemic hemodilution; Anesthesia; Cardiac: cardiopulmonary bypass; Dilutional coagulopathy; Infant

Indexed keywords

ALBUMIN; FIBRINOGEN; HEPARIN;

ARTICLE; BLOOD AUTOTRANSFUSION; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD CLOTTING TEST; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTAINER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DILUTION; HEMODILUTION; HEPARINIZATION; HUMAN; INFANT; INFUSION; INTERMETHOD COMPARISON; OPEN HEART SURGERY; OUTCOME ASSESSMENT; PEDIATRIC SURGERY; POSTOPERATIVE COMPLICATION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTHROMBIN TIME; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE COUNT;

ANTICOAGULANTS; BLOOD COAGULATION DISORDERS; BLOOD TRANSFUSION, AUTOLOGOUS; CARDIOPULMONARY BYPASS; FEMALE; FIBRINOGEN; HEMODILUTION; HEPARIN; HUMANS; INFANT; MALE; PLATELET COUNT; POSTOPERATIVE COMPLICATIONS; PROTHROMBIN TIME; TREATMENT OUTCOME;

EID: 33645105273     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2005.01805.x     Document Type: Article

References (24)

1. Bevan DH. Cardiac bypass haemostasis: putting blood through the mill Br J Haematol 1999 104 208 219
2. Kern FH Morana NJ Sears JJ et al. Coagulation defects in neonates during cardiopulmonary bypass Ann Thorac Surg 1992 54 541 546
3. Mohr R Golan M Martinowitz U et al. Effect of cardiac operation on platelets J Thorac Cardiovasc Surg 1986 92 434 441
4. Chan AKC Leaker M Burrows FA et al. Coagulation and fibrinolytic profile of paediatric patients undergoing cardiopulmonary bypass Thromb Haemost 1997 77 270 277
5. Friesen RH Tornabene MA Coleman SP. Blood conservation during pediatric cardiac surgery: ultrafiltration of the extracorporeal circuit volume after cardiopulmonary bypass Anesth Analg 1993 77 702 707
6. Manno CS Hedberg KW Kim HC et al. Comparison of the hemostatic effects of fresh whole blood, stored whole blood, and components after open heart surgery in children Blood 1991 77 930 936
7. McKenna R Bachmann F Whittaker B et al. The hemostatic mechanism after open-heart surgery. II. Frequency of abnormal platelet functions during and after extracorporeal circulation J Thorac Cardiovasc Surg 1975 70 298 308
8. Harker LA. Bleeding after cardiopulmonary bypass N Engl J Med 1986 314 1446 1448
9. Spiess BD. The contribution of fibrinolysis to postbypass bleeding J Cardiothorac Vasc Anesth 1991 5 (Suppl. 1) 13 17
10. Naik SK Knight A Elliott MJ. A successful modification of ultrafiltration for cardiopulmonary bypass in children Perfusion 1991 6 41 50
11. Friesen RH Campbell DN Clarke DR et al. Modified ultrafiltration attenuates dilutional coagulopathy in pediatric open heart operations Ann Thorac Surg 1997 64 1787 1789
12. Lavee J Martinowitz U Mohr R et al. The effect of transfusion of fresh whole blood versus platelet concentrates after cardiac operations J Thorac Cardiovasc Surg 1989 97 204 212
13. Mohr R Martinowitz U Lavee J et al. The hemostatic effect of transfusing fresh whole blood versus platelet concentrates after cardiac operations J Thorac Cardiovasc Surg 1988 96 530 534
14. Naik SK Knight A Elliott M. A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery Circulation 1991 84 Suppl. III 422 431
15. Shen I Giacomuzzi C Ungerleider RM. Current strategies for optimizing the use of cardiopulmonary bypass in neonates and infants Ann Thorac Surg 2003 75 S729 S734
16. D'Errico CC Shayevitz JR Martindale SJ et al. The efficacy and cost of aprotonin in children undergoing reoperative open heart surgery Anesth Analg 1996 83 1193 1199
17. Reid RW Zimmerman AA Laussen PC et al. The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery Anesth Analg 1997 84 990 996
18. Eisses MJ Seidel K Aldea GS et al. Reducing hemostatic activation during cardiopulmonary bypass: a combined approach Anesth Analg 2004 98 1208 1216
19. Kahraman S Altunkaya H Celebioglu B et al. The effect of acute normovolemic hemodilution on homologous blood requirements and total estimated red blood cell volume lost Acta Anaesthesiol Scand 1997 41 614 617
20. Casati V Benussi S Sandrelli L et al. Intraoperative moderate acute normovolemic hemodilution associated with a comprehensive blood-sparing protocol in off-pump coronary surgery Anesth Analg 2004 98 1217 1223
21. Martin E Ott E. Extreme hemodilution in the Harrington procedure Bibl Haematol 1981 47 322 337
22. Adzick NS deLorimier AA Harrison MR et al. Major childhood tumor resection using normovolemic hemodilution anesthesia and hetastarch J Pediatr Surg 1985 20 372 375
23. Murray DJ Pennell BJ Weinstein SL et al. Packed red cells in acute blood loss: dilutional coagulopathy as a cause of surgical bleeding Anesth Analg 1995 80 336 342
24. Hiippala ST Myllylä GJ Vahtera EM. Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates Anesth Analg 1995 81 360 365