Dual effect of flurbiprofen on cell proliferation and agonist-induced Ca2+ movement in human osteosarcoma cells

Basic and Clinical Pharmacology and Toxicology

Volumn 98, Issue 2, 2006, Pages 160-167

  Tseng, Li Ling ^a   Cheng, He Hsiung ^b   Huang, Chun Jen ^c,d   Liu, Shiuh Inn ^a   Kuo, Chun Chi ^e   Chen, Wei Chuan ^f   Huang, Jong Khing ^a   Hsu, Shu Shong ^a   Chang, Hong Tai ^a   Kao, Cheng Hsing ^b   Ho, Chin Man ^a   Jan, Chung Ren ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^e TZU HUI INSTITUTE OF TECHNOLOGY   (Taiwan)

^f Kaoahsiung Veterans General Hospital ^*

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; ADENOSINE TRIPHOSPHATE; BRADYKININ; CALCIUM; FLURBIPROFEN; HISTAMINE; THAPSIGARGIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL ORGANELLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; HUMAN; HUMAN CELL; INCUBATION TIME; INHIBITION KINETICS; METASTASIS; METASTASIS INHIBITION; OSTEOSARCOMA; OSTEOSARCOMA CELL; PRIORITY JOURNAL; REGULATORY MECHANISM;

ADENOSINE TRIPHOSPHATE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRADYKININ; CALCIUM; CELL LINE, TUMOR; CELL PROLIFERATION; FLURBIPROFEN; HISTAMINE; HUMANS; OSTEOSARCOMA; THAPSIGARGIN;

EID: 33645104321     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2006.pto_279.x     Document Type: Article

References (29)

1. Annunziato L. S. Amoroso A. Pannaccione M. Cataldi G. Pignataro A. D'Alessio R. Sirabella A. Secondo L. Sibaud G.F. Di Renzo Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions Toxicol. Lett. 2003 139 125 133
2. Barry E. L. Expression of mRNAs for the alpha 1 subunit of voltage-gated calcium channels in human osteoblast-like cell lines and in normal human osteoblasts Calcif. Tissue Int. 2000 66 145 150
3. Berridge M. J. Inositol trisphosphate and calcium signaling Nature 1993 361 315 325
4. Berridge M. J. Elementary and global aspects of calcium signalling J. Physiol. 1997 499 291 306
5. Bootman M. D. M. J. Berridge P. Lipp Cooking with calcium: the recipes for composing global signals from elementary events Cell 1993 91 367 373
6. Doroschak A. M. W. R. Bowles K. M. Hargreaves Evaluation of the combination of flurbiprofen and tramadol for management of endodontic pain J. Endod. 1999 25 660 663
7. Duncan R. L. K. A. Akanbi M. C. Farach-Carson Calcium signals and calcium channels in osteoblastic cells Semin. Nephrol. 1998 18 178 190
8. Fujimori A. M. Tsutsumi M. Fukase T. Fujita Cyclooxygenase inhibitors enhance cell growth in an osteoblastic cell line, MC3T3-E1 J. Bone Miner. Res. 1989 4 697 704
9. 2+ indicators with greatly improved fluorescence properties J. Biol. Chem. 1985 260 3440 3750
10. Gu Y. M. R. Preston A. J. El Haj J. Hamid G. W. Zamponi J. Howl S. J. Publicover Osteoblasts derived from load-bearing bones of the rat express both L- and T-like voltage-operated calcium channels and mRNA for alpha 1C, alpha 1D and alpha 1G subunits Pflügers Arch. 1999 438 553 560
11. 2+ channels in osteocytic (MLO-Y4) cells Biochem. Biophys. Res. Commun. 2001 282 536 542
12. 2+ increase in human osteosarcoma cells Pharmacology 2002 66 120 127
13. Jeffcoat M. K. M. S. Reddy S. Haigh W. Buchanan M. J. Doyle M. P. Meredith S. L. Nelson M. B. Goodale K. R. Wehmeyer A comparison of topical ketorolac, systemic flurbiprofen, and placebo for the inhibition of bone loss in adult periodontitis J. Periodontol. 1995 66 329 338
14. King J. G K. Khalili Jr.. Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen Oncogene 2001 20 6864 6870
15. Kuo S. Y. B. P. Jiann Y. C. Lu H. T. Chang W. C. Chen J. K. Huang C. R. Jan Thiol oxidation by 2,2′-dithiodipyridine induced calcium mobilization in MG63 human osteosarcoma cells Life Sci. 2003 72 1733 1743
16. Lee H. M. S. G. Ciancio G. Tuter M. E. Ryan E. Komaroff L. M. Golub Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug J. Periodontol. 2004 75 453 463
17. 2+ entry in MG63 human osteosarcoma cells Biochem. Pharmacol. 2001 61 1537 1541
18. 2+ movement in human osteosarcoma cells Pharmacology Toxicology 2002 91 34 39
19. MacNeil R. L. J. D'Errico C. Strayhorn H. Pickrum M. J. Somerman Agents with periodontal regenerative potential regulate cell-mediated collagen lattice contraction in vitro J. Dent. Res. 1996 75 903 911
20. McCracken J. D. W. J. Wechter Y. Liu R. L. Chase D. Kantoci E. D. Jr.. Murray D. D. Quiggle Y. Mineyama Antiproliferative effects of the enantiomers of flurbiprofen J. Clin. Pharmacol. 1996 36 540 545
21. 2+ channel in cultured bone marrow stromal cells by dexamethasone Calcif. Tissue Int. 1994 54 125 132
22. Putney J. W. Jr.. A model for receptor-regulated calcium entry Cell Calcium 1986 7 1 12
23. Rezzonico R. A. Schmid-Alliana G. Romey I. Bourget-Ponzio V. Breuil V. Breittmayer S. Tartare-Deckert B. Rossi H. Schmid-Antomarchi Prostaglandin E2 induces interaction between hSlo potassium channel and Syk tyrosine kinase in osteosarcoma cells J. Bone Miner. Res. 2002 17 869 878
24. Rogers H. J. R. G. Spector P. J. Morrison I. D. Bradbrook Comparative steady state pharmacokinetic study of piroxicam and flurbiprofen in normal subjects Eur. J. Rheumatol. Inflamm. 1981 4 303 308
25. Salvi G. E. N. P. Lang The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases Curr. Pharm. Des. 2005 11 1757 1769
26. Suresh D. K. K. L. Vandana D. S. Mehta Intracrevicular application of 0.3% Flurbiprofen gel and 0.3% Triclosan gel as antiinflammatory agent. A comparative clinical study Indian J. Dent. Res. 2001 12 105 112
27. Tegeder I. J. Pfeilschifter G. Geisslinger Cyclooxygenase-independent actions of cyclooxygenase inhibitors FASEB J. 2001 15 2057 2072
28. 2+-ATPase Proc. Natl. Acad. Sci. USA. 1990 87 2466 2470
29. 2+ mobilization in MG63 human osteosarcoma cells Horm. Res. 2001 55 265 270