Informed consent and collaborative research: Perspectives from the developing world

Developing World Bioethics

Volumn 6, Issue 1, 2006, Pages 33-40

  Hyder, Adnan A ^a   Wali, Salman A ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Developing world; Empirical ethics; Health systems; Informed consent; Research ethics

Indexed keywords

DEVELOPING COUNTRY; ETHICS; HEALTH EDUCATION; HUMAN; INFORMED CONSENT; INTERVIEW; MEDICAL RESEARCH; PRIORITY JOURNAL; QUESTIONNAIRE; RESEARCH; REVIEW; RISK;

BIOMEDICAL AND BEHAVIORAL RESEARCH; EMPIRICAL APPROACH; NATIONAL BIOETHICS ADVISORY COMMISSION;

ATTITUDE; CLINICAL PROTOCOLS; COMMUNITY-INSTITUTIONAL RELATIONS; COOPERATIVE BEHAVIOR; DATA COLLECTION; DEVELOPING COUNTRIES; DISCLOSURE; FOCUS GROUPS; HUMAN EXPERIMENTATION; HUMANS; INFORMED CONSENT; INTERNATIONAL COOPERATION; INTERVIEWS; RESEARCH PERSONNEL; THIRD-PARTY CONSENT; UNITED STATES;

EID: 33645099411     PISSN: 14718731     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-8847.2006.00134.x     Document Type: Review

References (27)

1. M. Angell Ethics of Clinical Research in Third World N Engl J Med 1997 337 847 499
2. P.E. Cleaton-Jones An Ethical Dilemma: Availability of Antiretroviral Therapy After Clinical Trials with HIV Infected Patients Are Ended BMJ 1997 314 887 891
3. M. Barry Ethical Considerations of Human Investigation in Developing Countries: the AIDS Dilemma N Engl J Med 1988 319 1083
4. M. Angell Ethical Imperialism-ethics in International Collaborative Clinical Research N Engl J Med 1988 319 1081 1083
5. P. Lurie S.M. Wolfe Unethical Trials of Interventions to Reduce Perinatal Transmission of the Human Immunodeficiency Virus in Developing Countries N Engl J Med 1997 337 853 855
6. Officefor Protection from Research Risks (OPRR). 1983. Protection of Human Subjects, 45 CFR 46. Washington, D.C. Department of Heath and Human Services. (GPO publication no. 0-406-756).
7. th ed. Oxford. Oxford University Press.
8. Councilof International Organizations of Medical Sciences (CIOMS). 2002. International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva. CIOMS in collaboration with the World Health Organisation (WHO).
9. Barry, op. cit. note 3.
10. N.A. Christakis The Ethical Design of an AIDS Vaccine Trial in Africa Hastings Cent Rep 1988 18 31 37
11. Barry, op. cit. note 3.
12. Christakis, op. cit. note 10.
13. Angell, op. cit. note 4.
14. C.B. Ijsselmuiden R.R. Faden Research and Informed Consent in Africa - Another Look N Engl J Med 1992 326 830 833
15. Adityanjee Informed consent: Issues Involved for Developing Countries Med Sci Law 1986 26 305 307
16. W. Holmes Informed Consent in Medical Research Minimum Ethical Standards Should Not Vary Among Countries. BMJ 1997 314 1479
17. N. Kass & A. Hyder. 2001. Attitudes and Experiences of U.S. and Developing Country Investigators Regarding U.S. Human Subject Regulations. Bethesda, MD. National Bioethics Advisory Commission.
18. Kass and Hyder, op. cit. note 17.
19. MicrosoftAccess 2000, © 1992-1999, Microsoft Corporation.
20. Epi-Infoversion 6.04(b), © 1997, Centers for Disease Control and Prevention, Atlanta, GA.
21. StataIntercooled, version 6.0, © 1984-1999, Stata Corporation, College Station, TX.
22. R.H. Bernard. 1994. Research Methods in Anthropology: Qualitative and Quantitative Approaches. Thousand Oaks, CA. Sage.
23. Atlas.ti, version 4.1, © 1997, Thomas Muhr, Scientific Software Development, Berlin.
24. Althoughthe survey population represented researchers from nearly ninety countries, it is not possible to present the complete list in current text. We have, however, listed a few countries from different regions that had a higher representation in the survey population. Initial cross-continent comparisons did not reveal any significant differences in responses from the researchers in respective regions.
25. Z.A. Bhutta Ethics in International Health Research: A Perspective from the Developing World Bull World Health Organ 2002 80 114 1120
26. G.B. Tangwa Globalisation or Westernisation? Ethical Concerns in the Whole Bio-business Bioethics 1999 13 218 226
27. L. London Ethical Oversight of Public Health Research: Can Rules and IRBs make a Difference in Developing Countries? Am J Public Health 2002 92 1079 1084