Heterotopic ossification and acetabular fractures

Current Opinion in Orthopaedics

Volumn 17, Issue 1, 2006, Pages 34-37

  Matityahu, Amir ^a   Bruck, Nathan ^a   Miclau, Theodore ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acetabular fracture; Heterotopic ossification; Heterotopic ossification prophylaxis; Indomethacin; Low dose radiation; Postoperative complication

Indexed keywords

INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT;

ACETABULUM FRACTURE; BLOOD CLOTTING DISORDER; CONFERENCE PAPER; DRUG HYPERSENSITIVITY; FRACTURE NONUNION; GENETIC DISORDER; HETEROTOPIC OSSIFICATION; HUMAN; INFERTILITY; KIDNEY FAILURE; LOW ENERGY RADIATION; MALIGNANT TRANSFORMATION; NONHUMAN; PATIENT; PRIORITY JOURNAL; PROPHYLAXIS; RADIOGRAPHY; RISK FACTOR; STOMACH ULCER; SURGICAL TECHNIQUE;

EID: 33645099237     PISSN: 10419918     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.bco.0000192520.48411.fa     Document Type: Conference Paper

References (34)

1. Tile M, Helfet DL, Kellam JF. Fractures of the Pelvis and Acetabulum. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 2003.
2. Moore KD, Goss K, Anglen JO. Indomethacin versus radiation therapy for prophylaxis against heterotopic ossification in acetabular fractures: a randomised, prospective study. J Bone Joint Surg Br 1998; 80:259-263.
3. Moed BR, Karges DE. Prophylactic indomethacin for the prevention of heterotopic ossification after acetabular fracture surgery in high-risk patients. J Orthop Trauma 1994; 8:34-39.
4. Moed BR, Maxey JW. The effect of indomethacin on heterotopic ossification following acetabular fracture surgery. J Orthop Trauma 1993; 7:33-38.
5. McLaren AC. Prophylaxis with indomethacin for heterotopic bone. After open reduction of fractures of the acetabulum. J Bone Joint Surg Am 1990; 72:245-247.
6. Letournel E, Judet R. Fractures of the Acetabulum. 2nd ed. New York: Springer-Verlag; 1993.
7. Burd TA, Lowry KJ, Anglen JO. Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures. J Bone Joint Surg Am 2001; 83-A:1783-1788.
8. Rath EM, Russell GV Jr, Washington WJ, Routt ML Jr. Gluteus minimus necrotic muscle debridement diminishes heterotopic ossification after acetabular fracture fixation. Injury 2002; 33:751-756.
9. Sawyer JR, Myers MA, Rosier RN, Puzas JE. Heterotopic ossification: clinical and cellular aspects. Calcif Tissue Int 1991; 49:208-215.
10. Chiu FY, Chen CM, Lo WH. Surgical treatment of displaced acetabular fractures - 72 cases followed for 10 [6-14] years. Injury 2000; 31:181-185.
11. Stockle U, Hoffmann R, Sudkamp NP, et al. Treatment of complex acetabular fractures through a modified extended iliofemoral approach. J Orthop Trauma 2002; 16:220-230.
12. Starr AJ, Watson JT, Reinert CM, et al. Complications following the "T extensile" approach: a modified extensile approach for acetabular fracture surgery-report of forty-three patients. J Orthop Trauma 2002; 16:535-542.
13. Kinik H, Armangil M. Extensile triradiate approach in the management of combined acetabular fractures. Arch Orthop Trauma Surg 2004; 124:476-482.
14. Cole JD, Bolhofner BR. Acetabular fracture fixation via a modified Stoppa limited intrapelvic approach. Description of operative technique and preliminary treatment results. Clin Orthop Relat Res 1994; 305:112-123.
15. Neal B, Gray H, MacMahon S, Dunn L. Incidence of heterotopic bone formation after major hip surgery. ANZ J Surg 2002; 72:808-821.
16. Matta JM, Siebenrock KA. Does indomethacin reduce heterotopic bone formation after operations for acetabular fractures? A prospective randomised study. J Bone Joint Surg Br 1997; 79:959-963.
17. Brooker AF, Bowerman JW, Robinson RA, Riley LH Jr. Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am 1973; 55:1629-1632.
18. Borrelli J Jr, Goldfarb C, Ricci W, et al. Functional outcome after isolated acetabular fractures. J Orthop Trauma 2002; 16:73-81.
19. Siebenrock KA, Gautier E, Woo AK, Ganz R. Surgical dislocation of the femoral head for joint debridement and accurate reduction of fractures of the acetabulum. J Orthop Trauma 2002; 16:543-552.
20. Kumar A, Shah NA, Kershaw SA, Clayson AD. Operative management of acetabular fractures. A review of 73 fractures. Injury 2005; 36:605-612. This paper describes fractures and the incidence of heterotopic ossification with the Kocher-Langenbach approach.
21. Morgan SJ, Jeray KJ, Phieffer LS, et al. Attitudes of orthopaedic trauma surgeons regarding current controversies in the management of pelvic and acetabular fractures. J Orthop Trauma 2001; 15:526-532.
22. Anglen JO, Moore KD. Prevention of heterotopic bone formation after acetabular fracture fixation by single-dose radiation therapy: a preliminary report. J Orthop Trauma 1996; 10:258-263.
23. Dudkiewicz I, Cohen I, Horowitz S, et al. Colchicine inhibits heterotopic ossification: experimental study in rabbits. Isr Med Assoc J 2005; 7:31-34. This paper describes animal models with a small case series.
24. Simon LS, Mills JA. Drug therapy: nonsteroidal antiinflammatory drugs (first of two parts). N Engl J Med 1980; 302:1179-1185.
25. Burd TA, Hughes MS, Anglen JO. Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion. J Bone Joint Surg Br 2003; 85:700-705.
26. Haas ML, Kennedy AS, Copeland CC, et al. Utility of radiation in the prevention of heterotopic ossification following repair of traumatic acetabular fracture. Int J Radiat Oncol Biol Phys 1999; 45:461-466.
27. Cornes PG, Shahidi M, Glees JP. Heterotopic bone formation: irradiation of high risk patients. Br J Radiol 2002; 75:448-452.
28. Childs HA 3rd, Cole T, Falkenberg E, et al. A prospective evaluation of the timing of postoperative radiotherapy for preventing heterotopic ossification following traumatic acetabular fractures. Int J Radiat Oncol Biol Phys 2000; 47:1347-1352.
29. Pellegrini VD Jr, Gregoritch SJ. Preoperative irradiation for prevention of heterotopic ossification following total hip arthroplasty. J Bone Joint Surg Am 1996; 78:870-881.
30. Schneider DJ, Moulton MJ, Singapuri K, et al. The Frank Stinchfield Award. Inhibition of heterotopic ossification with radiation therapy in an animal model. Clin Orthop Relat Res 1998; 355:35-46.
31. Kinsella TJ. Effects of radiation therapy and chemotherapy on testicular function. Prog Clin Biol Res 1989; 302:157-171 (discussion 172-7).
32. Holloway L, Hoban P, Metcalfe P. Radiobiological indices that consider volume: a review. Australas Phys Eng Sci Med 2002; 25:47-57.
33. Spinelli R. The role of scintigraphy in the diagnosis of late complications of total prosthesis of the hip. (Infection, loosening, ossification). Ital J Orthop Traumatol 1976; 2:79-87.
34. Abrahamsson SO, Ahlgren SA, Dahlstrom JA, et al. Ectopic bone after hip replacement. Excision and free fat transplants in four cases. Acta Orthop Scand 1984; 55:589-592.