-
1
-
-
1542376173
-
The transfer of a laboratory-based hypothesis to a clinically useful therapy: The development of anti-TNF therapy of rheumatoid arthritis
-
M. Feldmann et. al. The transfer of a laboratory-based hypothesis to a clinically useful therapy: The development of anti-TNF therapy of rheumatoid arthritis Best Pract. Res. Clin. Rheumatol. 18 2004 59-80
-
(2004)
Best Pract. Res. Clin. Rheumatol.
, vol.18
, pp. 59-80
-
-
Feldmann, M.1
-
2
-
-
0025274640
-
Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
-
W.P. Arend J.M. Dayer Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis Arthritis Rheum. 33 1990 305-315
-
(1990)
Arthritis Rheum.
, vol.33
, pp. 305-315
-
-
Arend, W.P.1
Dayer, J.M.2
-
3
-
-
0024314554
-
Inhibitory effect of TNF-alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
-
F.M. Brennan et. al. Inhibitory effect of TNF-alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis Lancet 2 1989 244-247
-
(1989)
Lancet
, vol.2
, pp. 244-247
-
-
Brennan, F.M.1
-
4
-
-
0028143211
-
Randomised double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
-
M.J. Elliott et. al. Randomised double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis Lancet 344 1994 1105-1110
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
-
5
-
-
17244364098
-
Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study
-
J.S. Smolen et. al. Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study Arthritis Rheum. 52 2005 1020-1030
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 1020-1030
-
-
Smolen, J.S.1
-
6
-
-
1642503128
-
IL-17 in rheumatoid arthritis: A new target for treatment or just another cytokine?
-
P. Miossec IL-17 in rheumatoid arthritis: A new target for treatment or just another cytokine? Joint Bone Spine 71 2004 87-90
-
(2004)
Joint Bone Spine
, vol.71
, pp. 87-90
-
-
Miossec, P.1
-
7
-
-
18644375615
-
Increased AP-1 and NF-kappaB activation and recruitment with the combination of the proinflammatory cytokines IL-1beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
-
C. Granet et. al. Increased AP-1 and NF-kappaB activation and recruitment with the combination of the proinflammatory cytokines IL-1beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes Arthritis Res. Ther. 6 2004 R190-R198
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Granet, C.1
-
8
-
-
13444254086
-
Interleukin-18: A therapeutic target in rheumatoid arthritis?
-
I.B. McInnes et. al. Interleukin-18: A therapeutic target in rheumatoid arthritis? Arthritis Res. Ther. 7 2005 38-41
-
(2005)
Arthritis Res. Ther.
, vol.7
, pp. 38-41
-
-
McInnes, I.B.1
-
9
-
-
0038685647
-
Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice
-
R.L. Smeets et. al. Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice Gene Ther. 10 2003 1004-1011
-
(2003)
Gene Ther.
, vol.10
, pp. 1004-1011
-
-
Smeets, R.L.1
-
10
-
-
0032939156
-
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by rheumatoid synovium
-
M. Chabaud et. al. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by rheumatoid synovium Arthritis Rheum. 42 1999 963-970
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
-
11
-
-
13444256307
-
The role of T cell interleukin-17 in conducting destructive arthritis: Lessons from animal models
-
E. Lubberts et. al. The role of T cell interleukin-17 in conducting destructive arthritis: Lessons from animal models Arthritis Res. Ther. 7 2005 29-37
-
(2005)
Arthritis Res. Ther.
, vol.7
, pp. 29-37
-
-
Lubberts, E.1
-
12
-
-
2942585608
-
Chemokine blockade: A new era in the treatment of rheumatoid arthritis?
-
J.J. Haringman P.P. Tak Chemokine blockade: A new era in the treatment of rheumatoid arthritis? Arthritis Res. Ther. 6 2004 93-97
-
(2004)
Arthritis Res. Ther.
, vol.6
, pp. 93-97
-
-
Haringman, J.J.1
Tak, P.P.2
-
13
-
-
4544222573
-
Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression
-
G. Page P. Miossec Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression J. Pathol. 204 2004 28-38
-
(2004)
J. Pathol.
, vol.204
, pp. 28-38
-
-
Page, G.1
Miossec, P.2
-
14
-
-
0242574700
-
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
-
J.M. Kremer et. al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig N. Engl. J. Med. 349 2003 1907-1915
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 1907-1915
-
-
Kremer, J.M.1
-
15
-
-
0037165261
-
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma
-
B. Coiffier et. al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma N. Engl. J. Med. 346 2002 235-242
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 235-242
-
-
Coiffier, B.1
-
16
-
-
2942537697
-
Efficacy of B cell-targeted therapy with rituximab in patients with rheumatoid arthritis
-
J.C. Edwards et. al. Efficacy of B cell-targeted therapy with rituximab in patients with rheumatoid arthritis N. Engl. J. Med. 350 2004 2572-2581
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2572-2581
-
-
Edwards, J.C.1
-
17
-
-
2442676277
-
Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor
-
L.F. Bovin et. al. Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor Immunol. Lett. 93 2004 217-226
-
(2004)
Immunol. Lett.
, vol.93
, pp. 217-226
-
-
Bovin, L.F.1
-
18
-
-
1942532229
-
Technical validation of cDNA-based microarray as screening technique to identify candidate genes in synovial tissue biopsy specimens from patients with spondyloarthropathy
-
M. Rihl et. al. Technical validation of cDNA-based microarray as screening technique to identify candidate genes in synovial tissue biopsy specimens from patients with spondyloarthropathy Ann. Rheum. Dis. 63 2004 498-507
-
(2004)
Ann. Rheum. Dis.
, vol.63
, pp. 498-507
-
-
Rihl, M.1
-
19
-
-
0031445542
-
Th1/Th2 cytokine balance in arthritis
-
P. Miossec W. van den Berg Th1/Th2 cytokine balance in arthritis Arthritis Rheum. 40 1997 2105-2115
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 2105-2115
-
-
Miossec, P.1
van den Berg, W.2
-
20
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF-alpha therapy
-
M.R. Ehrenstein et. al. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF-alpha therapy J. Exp. Med. 200 2004 277-285
-
(2004)
J. Exp. Med.
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
|