In vivo monitoring of DNA vaccine gene expression using firefly luciferase as a naked DNA

Vaccine

Volumn 24, Issue 16, 2006, Pages 3057-3062

  Jeon, Yong Hyun ^a   Choi, Yun ^a   Kang, Joo Hyun ^a   Chung, June Key ^a   Lee, Yong Jin ^a   Kim, Chul Woo ^a   Jeong, Jae Min ^a   Lee, Dong Soo ^a   Lee, Myung Chul ^a  

^a Seoul National University   (South Korea)

Author keywords

DNA vaccine gene expression; Firefly luciferase; In vivo visualization

Indexed keywords

DNA VACCINE; FIREFLY LUCIFERASE; MESSENGER RNA; NAKED DNA;

ANIMAL EXPERIMENT; ARTICLE; BIOLUMINESCENCE; FEMALE; GENE EXPRESSION; IN VIVO STUDY; INGUINAL LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; FEMALE; GENE EXPRESSION; GENES, REPORTER; IMAGE PROCESSING, COMPUTER-ASSISTED; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; LYMPH NODES; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VACCINES, DNA;

EID: 33645077606     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.01.033     Document Type: Article

References (20)

1. M. Manthorpe, F. Cornefert-Jensen, J. Hartikka, J. Felgner, A. Rundell, and M. Margalith Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice Hum Gene Ther 4 4 1993 419 431
2. J.B. Ulmer, J.J. Donnelly, S.E. Parker, G.H. Rhodes, P.L. Felgner, and V.J. Dwarki Heterologous protection against influenza by injection of DNA encoding a viral protein Science 259 5102 1993 1745 1749
3. J.A. Wolff, R.W. Malone, P. Williams, W. Chong, Q. Acsadi, and A. Jani Direct gene transfer into mouse muscle in vivo Science 247 4949 Pt 1 1990 1465 1468
4. K.K. Peachman, M. Rao, and C.R. Alving Immunization with DNA through the skin Methods 31 3 2003 232 242
5. M. Dupuis, K. Denis-Mize, C. Woo, C. Goldbeck, M.J. Selby, and M. Chen Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice J Immunol 165 5 2000 2850 2858
6. P. Forg, P. von Hoegen, W. Dalemans, and V. Schirrmacher Superiority of the ear pinna over muscle tissue as site for DNA vaccination Gene Ther 5 6 1998 789 797
7. U.R. Hengge, P.S. Walker, and J.C. Vogel Expression of naked DNA in human, pig, and mouse skin J Clin Invest 97 12 1996 2911 2916
8. S. Maeda, K. Ohmori, K. Kurata, M. Sakaguchi, K. Masuda, and K. Ohno Expression of LacZ gene in canine muscle by intramuscular inoculation of a plasmid DNA J Vet Med Sci 66 3 2004 337 339
9. T. Wilson, and J.W. Hastings Bioluminescence. Annu Rev Cell Dev Biol 14 1998 197 230
10. A. Honigman, E. Zeira, P. Ohana, R. Abramovitz, E. Tavor, and I. Bar Imaging transgene expression in live animals Mol Ther 4 3 2001 239 249
11. A. De, X.Z. Lewis, and S.S. Gambhir Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice Mol Ther 7 5 Pt 1 2003 681 691
12. P. Ray, E. Bauer, M. Iyer, J.R. Barrio, N. Satyamurthy, and M.E. Phelps Monitoring gene therapy with reporter gene imaging Semin Nucl Med 31 4 2001 312 320
13. P. Ray, A. De, J.J. Min, R.Y. Tsien, and S.S. Gambhir Imaging tri-fusion multimodality reporter gene expression in living subjects Cancer Res 64 4 2004 1323 1330
14. C.H. Contag, D. Jenkins, P.R. Contag, and R.S. Negrin Use of reporter genes for optical measurements of neoplastic disease in vivo Neoplasia 2 1-2 2000 41 52
15. D.E. Jenkins, Y.S. Hornig, Y. Oei, J. Dusich, and T. Purchio Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice Breast Cancer Res 7 4 2005 R444 R454
16. C.D. Scatena, M.A. Hepner, Y.A. Oei, J.M. Dusich, S.F. Yu, and T. Purchio Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer Prostate 59 3 2004 292 303
17. D.E. Jenkins, S.F. Yu, Y.S. Hornig, T. Purchio, and P.R. Contag In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer Clin Exp Metastasis 20 8 2003 745 756
18. C. Trimble, C.T. Lin, C.F. Hung, S. Pai, J. Juang, and L. He Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe Vaccine 21 25-26 2003 4036 4042
19. U.R. Hengge, B. Dexling, and A. Mirmohammadsadegh Safety and pharmacokinetics of naked plasmid DNA in the skin: studies on dissemination and ectopic expression J Invest Dermatol 116 6 2001 979 982
20. S. Satkauskas, M.F. Bureau, A. Mahfoudi, and L.M. Mir Slow accumulation of plasmid in muscle cells: supporting evidence for a mechanism of DNA uptake by receptor-mediated endocytosis Mol Ther 4 4 2001 317 323