Synaptic hyperexcitability of deep layer neocortical cells in a genetic model of absence seizures

Genes, Brain and Behavior

Volumn 5, Issue 1, 2006, Pages 73-84

  D'Antuono, M ^a,b   Inaba, Y ^c   Biagini, G ^d   D'Arcangelo, G ^e   Tancredi, V ^e   Avoli, M ^a,b,c,f  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

^f NONE   (Canada)

Author keywords

Absence epilepsy; Neocortex; NMDA receptors; Pyramidal cells; WAG Rij rat

Indexed keywords

3,3 (2 CARBOXYPIPERAZIN 4 YL)PROPYL 1 PHOSPHONATE; GLUTAMATE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; 3,3 (2 CARBOXYPIPERAZINE 4 YL)PROPYL 1 PHOSPHONATE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN SLICE; CELL SHAPE; CONTROLLED STUDY; DENDRITIC CELL; ELECTRODE; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; EPILEPTIC DISCHARGE; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; IN VIVO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; INTRACELLULAR RECORDING; ION CONDUCTANCE; NEOCORTEX; NONHUMAN; PIA MATER; PRIORITY JOURNAL; RAT; RAT STRAIN; SEIZURE; SYNAPSE; WHITE MATTER; ABSENCE; DENDRITIC SPINE; GENETIC MODEL; HYPERPOLARIZATION; MICROELECTRODE; NERVE CELL; NERVE CELL EXCITABILITY; NERVE POTENTIAL; SPIKE WAVE; SYNAPTIC POTENTIAL;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGY; EPILEPSY, ABSENCE; MATCHED-PAIR ANALYSIS; NEOCORTEX; NEURAL PATHWAYS; NEURONS; RATS; RATS, INBRED STRAINS; RATS, WISTAR; SOMATOSENSORY CORTEX; SYNAPTIC TRANSMISSION;

ANIMALIA;

EID: 33645071575     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2005.00146.x     Document Type: Article

References (48)

1. Agmon A. Connors B.W. 1991 Correlation between intrinsic firing patterns and thalamocortical synaptic responses of neurons in mouse barrel cortex J Neurosci 12 319 329
2. Andersson O. Stenqvist A. Attersand A. von Euler G. 2001 Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B Genomics 78 178 184
3. Avoli M. Gloor P. Kostopoulos G. Gotman J. 1983 An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons J Neurophysiol 50 819 837
4. Avoli M. Rogawski M.A. Avanzini G. 2001 Generalized epileptic disorders: an update Epilepsia 42 445 457
5. Chagnac-Amitai Y. Luhmann H.J. Prince D.A. 1990 Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological features J Comp Neurol 296 598 613
6. Coenen A.M. van Luijtelaar E.L. 2003 Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats Behav Genet 33 635 655
7. Contreras D. Steriade M. 1995 Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships J Neurosci 15 604 622
8. Crunelli V. Leresche N. 2002 Childhood absence epilepsy: genes, channels, neurons and networks Nat Rev Neurosci 3 371 382
9. D'Antuono M. Biagini G. Tancredi V. Avoli M. 2001 Electrophysiology of regular firing cells in the rat perirhinal cortex Hippocampus 11 662 672
10. D'Arcangelo G. D'Antuono M. Biagini G. Warren R. Tancredi V. Avoli M. 2002 Thalamocortical oscillations in a genetic model of absence seizures Eur J Neurosci 16 2383 2393
11. Deschênes M. Veinante P. Zhang Z.W. 1998 The organization of corticothalamic projections: reciprocity versus parity Brain Res Brain Res Rev 28 286 308
12. Drinkenburg W.H. van Luijtelaar E.L. van Schaijk W.J. Coenen A.M. 1993 Aberrant transients in the EEG of epileptic rats: a spectral analytical approach Physiol Behav 54 779 783
13. Gallitto G. Mugolino R. Aliquo G. Bruno A. De Domenico P. Marlara C.E. Marabello L. Pugliesi R.M. Sturniolo R. Di Perri R. 1987 Pentylenetetrazol- induced spike wave discharges in rats: a polygraphic study Ital J Neurol Sci 8 143 150
14. Gauguier D. van Luijtelaar G. Bihoreau M.T. Wilder S.P. Godfrey R.F. Vossen J. Coenen A. Cox R.D. 2004 Chromosomal mapping of genetic loci controlling absence epilepsy phenotypes in the WAG/Rij rat Epilepsia 45 908 915
15. Gloor P. 1969 Neurophysiological bases of generalized seizures termed centrencephalic. In Gastaut H. Jasper H. Bancaud J. Waltregny A. (eds) The Physiopathogenesis of the Epilepsies Charles C Thomas Springfield, IL, pp. 209 236
16. Kita H. Armstrong W. 1991 A biotin-containing compound N-(2-aminoethyl) biotinamide for intracellular labeling and neuronal tracing studies: comparison with biocytin J Neurosci Methods 37 141 150
17. Klioueva I.A. van Luijtelaar E.L. Chepurnova N.E. Chepurnov S.A. 2001 PTZ-induced seizures in rats: effects of age and strain Physiol Behav 72 421 426
18. Kostopoulos G. Avoli M. Gloor P. 1983 Participation of cortical recurrent inhibition in the genesis of spike and wave discharges in feline generalized penicillin epilepsy Brain Res 267 101 112
19. Larkman A. Mason A. 1990 Correlations between morphology and electrophysiology of pyramidal neurons in slices of rat visual cortex. I. Establishment of cell classes J Neurosci 10 1407 1414
20. Lennox W.G. Lennox M.A. 1960 Epilepsy and Related Disorders Little Brown Boston
21. Luhmann H.J. Mittmann T. van Luijtelaar G. Heinemann U. 1995 Impairment of intracortical GABAergic inhibition in a rat model of absence epilepsy Epilepsy Res 22 43 51
22. van Luijtelaar E.L.J.M. Coenen A.M.L. 1986 Two types of electrocortical paroxysms in an inbred strain of rats Neurosci Lett 70 393 397
23. Manning J.P. Richards D.A. Leresche N. Crunelli V. Bowery N.G. 2003 Cortical-area specific block of genetically determined absence seizures by ethosuximide Neuroscience 123 5 9
24. Marescaux C. Micheletti G. Vergnes M. Depaulis A. Rumbach L. Warter J.M. 1985 A model of chronic spontaneous petit mal-like seizures in the rat: comparison with pentylenetetrazol-induced seizures Epilepsia 25 326 331
25. Mason A. Larkman A. 1990 Correlations between morphology and electrophysiology of pyramidal neurons in slices of rat visual cortex. II. Electrophysiology J Neurosci 10 1415 1428
26. McCormick D.A. Connors B.W. Lighthall J.W. Prince D.A. 1985 Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex J Neurophysiol 54 782 806
27. Meeren H.K. Pijn J.P. van Luijtelaar E.L. Coenen A.M. Lopes da Silva F. 2002 Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats J Neurosci 22 1480 1495
28. Metrakos K. Metrakos J.D. 1961 Genetics of convulsive disorders, II: genetic and electroencephalographic studies in centrencephalic epilepsy Neurology (Minneap) 11 464 483
29. Midzianovskaia I.S. Kuznetsova G.D. Coenen A.M. Spiridonov A.M. van Luijtelaar E.L. 2001 Electrophysiological and pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats Brain Res 911 62 70
30. Mock B. Kozak C. Seldin M.F. Ruff N. D'Hoostelaere L. Szpirer C. Levan G. Seuanez H. O'Brien S. Banner C. 1989 A glutaminase (gis) gene maps to mouse chromosome 1, rat chromosome 9, and human chromosome 2 Genomics 5 291 297
31. Neckelmann D. Amzica F. Steriade M. 1998 Spike-wave complexes and fast components of cortically generated seizures. III. Synchronizing mechanisms J Neurophysiol 80 1480 1494
32. Noebels J.L. 2003 Exploring new gene discoveries in idiopathic generalized epilepsy Epilepsia 44 16 21
33. Panayiotopoulos C.P. 1999 Typical absence seizures and their treatment Arch Dis Child 81 351 355
34. Paxinos G. Watson C. 1998 The Rat Brain in Stereotaxic Coordinates 4th edn Academic Press San Diego
35. Peeters B.W.M.M. van Rijn C.M. van Luijtelaar E.L.J.M. Coenen A.M.L. 1989 Antiepileptic and behavioural actions of MK-801 in an animal model of spontaneous absence epilepsy Epilepsy Res 3 178 181
36. Peeters B.W.M.M. van Rijn C.M. Vossen J.M.H. Coenen A.M.L. 1990 Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats Life Sci 47 523 529
37. Peeters B.W.M.M. Kerbusch J.M. Coenen A.M. Vossen J.M. van Luijtelaar E.L. 1992 Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: a classical mendelian crossbreeding study Behav Genet 22 361 368
38. Pinault D. 2003 Cellular interactions in the rat somatosensory thalamocortical system during normal and epileptic 5-9 Hz oscillations J Physiol (Lond) 552 881 905
39. Pumain R. Louvel J. Gastard M. Kurcewicz I. Vergnes M. 1992 Responses to N-methyl-D-aspartate are enhanced in rats with Petit-mal-like seizures J Neural Transm Suppl 35 97 108
40. Seidenbecher T. Staak R. Pape H.C. 1998 Relations between cortical and thalamic cellular activities during absence seizures in rats Eur J Neurosci 10 1103 1112
41. Steriade M. Contreras D. 1998 Spike-wave complexes and fast components of cortically generated seizures. I. Role of neocortex and thalamus J Neurophysiol 80 1439 1455
42. Steriade M. Amzica F. Neckelmann D. Timofeev I. 1998 Spike-wave complexes and fast components of cortically generated seizures. II. Extra- and intracellular patterns J Neurophysiol 80 1456 1479
43. Szpirer C. Riviere M. Szpirer J. Genet M. Dreze P. Islam M.Q. Levan G. 1990 Assignment of 12 loci to rat chromosome 5: evidence that this chromosome is homologous to mouse chromosome 4 and to human chromosomes 9 and 1 (1p arm) Genomics 6 679 684
44. Thomson A.M. West D.C. 1986 N-methylaspartate receptors mediate epileptiform activity evoked in some, but not all, conditions in rat neocortical slices Neuroscience 19 1161 1177
45. Timofeev I. Grenier F. Steriade M. 1998 Spike-wave complexes and fast components of cortically generated seizures. IV. Paroxysmal fast runs in cortical and thalamic neurons J Neurophysiol 80 1495 1513
46. Tolmacheva E.A. van Luijtelaar G. Chepurnov S.A. Kaminskij Y. Mares P. 2004 Cortical and limbic excitability in rats with absence epilepsy Epilepsy Res 62 189 198
47. Veinante P. Lavallee P. Deschenes M. 2000 Corticothalamic projections from layer 5 of the vibrissal barrel cortex in the rat J Comp Neurol 424 197 204
48. Vergnes M. Marescaux C. Depaulis A. Micheletti G. Warter J.M. 1990 Spontaneous spike-wave discharges in wistar rats: a model of genetic generalized convulsive epilepsy. In Avoli M. Gloor P. Kostopoulos G. Naquet R. (eds) Generalized Epilepsy: Neurobiological Approaches Birkhäuser Boston, pp. 238 253