The role of residue stability in transient protein-protein interactions involved in enzymatic phosphate hydrolysis. A computational study

Proteins: Structure, Function and Genetics

Volumn 63, Issue 1, 2006, Pages 65-77

  Bonet, Jaume ^a   Caltabiano, Gianluigi ^a   Khan, Abdul Kareem ^a   Johnston, Michael A ^a   Corbí, Carles ^a   Gómez, Àlex ^a   Rovira, Xavier ^a   Teyra, Joan ^a   Villà Freixa, Jordi ^a  

^a INST MUNIC D INVESTIGACIO MEDICA   (Spain)

Author keywords

Enzyme phosphate hydrolysis; Residue stability; Transient protein protein interactions

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE 2; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHOSPHATE; RAS PROTEIN; WATER;

AMINO ACID SEQUENCE; ARTICLE; CALCULATION; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CORRELATION COEFFICIENT; DIPOLE; ELECTRICITY; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; HYDROLYSIS; MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SURFACE PROPERTY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; COMPUTATIONAL BIOLOGY; CYCLIN A; CYCLIN-DEPENDENT KINASE 2; CYCLINS; ELECTROSTATICS; ENZYMES; GTP PHOSPHOHYDROLASES; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHOSPHATES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEINS; PROTEOMICS; SOFTWARE; THERMODYNAMICS;

EID: 33645021132     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.20791     Document Type: Article

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