Functional and molecular alterations in T cells induced by CCL5

Immunological Investigations

Volumn 35, Issue 1, 2006, Pages 115-132

  Cridge, T J ^a   Horowitz, K M ^a   Marinucci, M N ^a   Rose, K M ^a   Wells, M ^a   Werner, M T ^a   Kurt, Robert A ^a  

^a LAFAYETTE COLLEGE   (United States)

Author keywords

CCL5; Lipid Rafts; RANTES; T cells; TCR translocation

Indexed keywords

CD3 ANTIBODY; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHOLERA TOXIN B SUBUNIT; CYTOKINE; DNA; F ACTIN; G ACTIN; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; RANTES; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; LIPID RAFT; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE;

ACTINS; ANIMALS; CHEMOKINES, CC; CYTOKINES; FEMALE; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED BALB C; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, T-CELL; SPLEEN; T-LYMPHOCYTES;

EID: 33644978128     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.1080/08820130500514365     Document Type: Article

References (35)

1. Adler, E. P., Lemken, C. A., Katchen, N. S., Kurt, R. A. (2003). A dual role for tumor-derived RANTES (CCL5). Immunol. Lett. 90:187-194.
2. Antes, P., Schwarzmann, G., Sandhoff, K. (1992). Detection of protein mediated glycosphingolipid clustering by the use of resonance energy transfer between fluorescent labelled lipids. A method established by applying the system ganglioside GM1 and cholera toxin B subunit. Chem. Phys. Lipids. 62:269-280.
3. Azenshtein, E., Luboshits, G., Shina, S., Neumark, E., Shahbazian, D., Weil, M., Wigler, N., Keydar, I., Ben-Baruch, A. (2002). The CC chemokine RANTES in breast carcinoma progression: regulation of expression and potential mechanisms of promalignant activity. Cancer Res 62:1093-1102.
4. Bacon, K. B., Premack, B. A., Gardner, P., Schall, T. J. (1995). Activation of dual T cell signaling pathways by the chemokine RANTES. Science 269:1727-1730.
5. Barnden, M. J., Allison, J., Heath, W. R., Carbone, F. R. (1998). Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76:34-40.
6. de Lamos, C., Christensen, J. E., Nansen, A., Moos, T., Lu, B., Gerard, C., Christensen, J. P., Thomsen, A. R. (2005). Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice. J. Immunol. 175:1767-1775.
7. Fischer, F. R., Luo, Y., Luo, M., Santambrogio, L., Dorf, M. E. (2001). RANTES-induced chemokine cascade in dendritic cells. J. Immunol. 167:1637-1643.
8. Ieki, K., Matsukura, S., Kokubu, F., Kimura, T., Kuga, H., Kawaguchi, M., Odaka, M., Suzuki, S., Watanabe, S., Takeuchi, H., Schleimer, R. P., Adachi, M. (2004). Double-stranded RNA activates RANTES gene transcription through co-operation of nuclear factor-kappaB and interferon regulatory factors in human airway epithelial cells. Clin. Exp. Allergy. 34:745-752.
9. Jung, S., Littman, D. R. (1999). Chemokine receptors in lymphoid organ homeostasis. Curr. Opin. Immunol. 11:319-325.
10. Kameyoshi, Y., Dorschner, A., Mallet, A. I., Chrisophers, E., Schroder, J. M. (1992). Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. J. Exp. Med. 176:587-592.
11. Kurt, R. A., Baher, A., Wisner, K. P., Tackitt, S., Urba, W. J. (2001). Chemokine receptor desensitization in tumor-bearing mice. Cell. Immunol. 207:81-88.
12. Kurt, R. A., Bauck, M., Harma, S., Adler, E., Vitiello, P., Wisner, K. P., Tackitt, S., Urba, W. J. (2003). Altered chemokine receptor sensitivity in FVBN202 rat neu transgenic mice. Breast Cancer Res. Treat. 77:225-232.
13. Locati, M., Deuschle, U., Massardi, M. L., Martinez, F. O., Sironi, M., Sozzani, S., Bartfai, T., Mantovani, A. (2002). Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes. J. Immunol. 168:3557-3562.
14. Luboshits, G., Shina, S., Kaplan, O., Engelberg, S., Nass, D., Lifshitz-Mercer, B., Chaitchik, S., Keydar, I., Ben-Baruch, A. (1999). Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma. Cancer Res 59:4681-4687.
15. Makino, Y., Cook, D. N., Smithies, O., Hwang, O. Y., Neilson, E. G., Turka, L. A., Sato, H., Wells, A. D., Danoff, T. M. (2002). Impaired T cell function in RANTES-deficient mice. Clin. Immunol. 102:302-309.
16. Mashikian, M. V., Ryan, T. C., Seman, A., Brazer, W., Center, D. M., Cruikshank, W. W. (1999). Reciprocal desensitization of CCR5 and CD4 is mediated by IL-16 and macrophage-inflammatory protein-1beta, respectively. J. Immunol. 163:3123-3130.
17. Morris, A. J., Malbon, C. C. (1999). Physiological regulation of G protein-linked signaling. Physiol. Rev. 79:1373-1430.
18. Niwa, Y., Akamatsu, H., Niwa, H., Sumi, H., Ozaki, Y., Abe, A. (2001). Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer. Clin. Cancer. Res. 7:285-289.
19. Proudfoot, A. E. I., Buser, R., Borlat, F., Alouani, S., Soler, D., Offord, R. E., Schroder, J., Power, C. A., Wells, T. N. C. (1999). Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors. J. Biol. Chem. 274:32478-32485.
20. Riffo-Vasquez, Y., Spina, D. (2002). Role of cytokines and chemokines in bronchial hyperresponsiveness and airway inflammation. Pharmacol. Ther. 94:185-211.
21. Rosa, G., Longo, N., Rodriguez-Fernandez, J. L., Puig-Kroger, A., Pineda, A., Corbi, A. L., Sanchez-Mateos, P. (2003). Migration of human blood dendritic cells across endothelial cell monolayers: adhesion molecules and chemokines involved in subset-specific transmigration. J. Leukoc. Biol. 73:639-649.
22. Roth, S. J., Carr, M. W., Springer, T. A. (1995). C-C chemokines, but not the C-X-C chemokines interleukin-8 and interferon-gamma inducible protein-10, stimulate transendothelial chemotaxis of T lymphocytes. Eur. J. Immunol. 25:3482-3488.
23. Sanzenbacher, R., Kabelitz, D., Janssen, O. (1999). SLP-76 binding to p56lck: a role for SLP-76 in CD4-induced desensitization of the TCR/CD3 signaling complex. J. Immunol. 163:3143-3152.
24. Schall, T. J., Bacon, K., Toy, K. J., Goeddel, D. V. (1990). Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669-671.
25. Schall, T. J., Jongstra, J., Dyer, B. J., Jorgensen, J., Clayberger, C., Davis, M. M., Krensky, A. M. (1988). A human T cell-specific molecule is a member of a new gene family. J. Immunol. 141:1018-1025.
26. Shakoory, B., Fitzgerald, S. M., Lee, S. A., Chi, D. S., Krishnaswamy, G. (2004). The role of human mast cell-derived cytokines in eosinophil biology. J. Interferon Cytokine Res. 24:271-281.
27. Siveke, J. T., Hamann, A. (1998). T helper 1 and T helper 2 cells respond differentially to chemokines. J. Immunol. 160:550-554.
28. Staudinger, R., Phogat, S. K., Xiao, X., Wang, X., Dimitrov, D. S., Zolla-Pazner, S. (2003). Evidence for CD4-enhanced signaling through the chemokine receptor CCR5. J. Biol. Chem. 278:10389-10392.
29. Stormes, K. A., Lemken, C. A., Lepre, J. V., Marinucci, M. N., Kurt, R. A. (2005). Inhibition of metastasis by inhibition of tumor-derived CCL5. Breast Cancer Res. Treat. 89:209-212.
30. Szekanecz, Z., Kim, J., Koch, A. E. (2003). Chemokines and chemokine receptors in rheumatoid arthritis. Semin. Immunol. 15:15-21.
31. Taub, D. D., Sayers, T. J., Carter, C. R., Ortaldo, J. R. (1995). Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J. Immunol. 155:3877-3888.
32. Ticchioni, M., Charvet, C., Noraz, N., Lamy, L., Steinberg, M., Bernard, A., Deckert, M. (2002). Signaling through ZAP-70 is required for CXCL12-mediated T-cell transen-dothelial migration. Blood 99:3111-3118.
33. Van Drenth, C., Jenkins, A., Ledwich, L., Ryan, T. C., Mashikian, M. V., Brazer, W., Center, D. M., Cruikshank, W. W. (2000). Desensitization of CXC chemokine receptor 4, mediated by IL-16/CD4, is independent of p56lck enzymatic activity. J. Immunol. 165:6356-6363.
34. Welniak, L. A., Wang, Z., Sun, K., Kuziel, W., Anver, M. R., Blazar, B. R., Murphy, W. J. (2004). An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease. Exp. Hematol. 32:318-324.
35. Xiao, X., Wu, L., Stantchev, T. S., Feng, Y. R., Ugolini, S., Chen, H., Shen, Z., Riley, J. L., Broder, C. C., Sattentau, Q. J., Dimitrov, D. S. (1999). Constitutive cell surface association between CD4 and CCR5. Proc. Natl. Acad. Sci. USA. 96:7496-7501.