Continuous infusion of 0.5% bupivacaine for local analgesia: What are "toxic" blood levels? [6]

Regional Anesthesia and Pain Medicine

Volumn 31, Issue 2, 2006, Pages 184-

  White, Paul F ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE;

DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; HEART ARRHYTHMIA; HEART DISEASE; HUMAN; LETTER; LOCAL ANESTHESIA; PRIORITY JOURNAL; TOTAL KNEE REPLACEMENT;

ANESTHESIA, CONDUCTION; ANESTHETICS, LOCAL; BUPIVACAINE; HUMANS; INFUSION PUMPS; RANDOMIZED CONTROLLED TRIALS;

EID: 33644976912     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rapm.2005.08.005     Document Type: Letter

References (4)

1. M.A. Hoeft, J.P. Rathmell, M.R. Dayton, P. Lee, J.G. Howe, S.J. Incavo, J.F. Lawlis Continuous, intra-articular infusion of bupivacaine after total-knee arthroplasty may lead to potentially toxic serum levels of local anesthetic Reg Anesth Pain Med 30 2005 414 415
2. L.J. Hasselstrøm, T. Morgensen Toxic reaction of bupivacaine at low plasma concentration Anesthesiology 61 1984 99 100
3. D.C. Moore, G.E. Thompson, R.D. Crawford Long acting local anesthetic drugs and convulsions with hypoxia and acidosis Anesthesiology 56 1982 230 232
4. P.F. White, S. Rawal, P. Latham, S. Markowitz, T. Issioui, L. Chi, S. Dellaria, C. Shi, L. Morse, C. Ing Use of a continuous local anesthetic infusion for pain management after median sternotomy Anesthesiology 99 2003 918 923