Synthesis and antiinflammatory activity of 4-amino-2-aryl-5-cyano-6-{3- and 4-(N-phthalimidophenyl)} pyrimidines

European Journal of Medicinal Chemistry

Volumn 41, Issue 2, 2006, Pages 276-282

  Falcão, Emerson Peter Da S ^a   De Melo, Sebastião J ^a   Srivastava, Rajendra M ^a   Catanho, Maria Tereza Jansen De A ^a   Do Nascimento, Silene Carneiro ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Antiinflammatory activity; Bisnitriles; Pyrimidines

Indexed keywords

4 AMINO 2 (4 ANISYL) 5 CYANO 6 (4 NITROPHENYL)PYRIMIDINE; 4 AMINO 2 (4 ANISYL) 5 CYANO 6 [4 (N PHTHALIMIDOPHENYL)]PYRIMIDINE; 4 AMINO 2 (4 ANISYL) 6 (4 ANISYL) 5 CYANOPYRIMIDINE; 4 AMINO 2 (4 CHLOROPHENYL) 5 CYANO 6 (4 NITROPHENYL)PYRIMIDINE; 4 AMINO 2 (4 CHLOROPHENYL) 5 CYANO 6 [3 (N PHTHALIMIDOPHENYL)]PYRIMIDINE; 4 AMINO 5 CYANO 2 (4 CHLOROPHENYL) 6 (3 NITROPHENYL)PYRIMIDINE; 4 AMINO 5 CYANO 2 (4 CHLOROPHENYL) 6 [4 (N PHTHALIMIDOPHENYL)]PYRIMIDINE; 4 AMINO 5 CYANO 2 (4 FLUOROPHENYL) 6 (4 NITROPHENYL)PYRIMIDINE; 4 AMINO 5 CYANO 2 (4 FLUORPHENYL) 6 [4 (N PHTHALIMIDOPHENYL)]PYRIMIDINE; 4 AMINO 5 CYANO 2 (PHENYL) 6 [4 (N PHTHALIMIDOPHENYL)]PYRIMIDINE; 4 AMINO 5 CYANO 6 (4 NITROPHENYL) 2 (4 PHENYL)PYRIMIDINE; ACETIC ACID ETHYL ESTER; ACETYLSALICYLIC ACID; AMIDINE; HETEROCYCLIC COMPOUND; INDOMETACIN; NITRILE; PALLADIUM; PHTHALIC ANHYDRIDE; PHTHALIMIDE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LARYNX TUMOR; MASS SPECTROMETRY; MOUSE; NONHUMAN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; TUMOR CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CYTOTOXICITY TESTS, IMMUNOLOGIC; MICE; MICROBIAL SENSITIVITY TESTS; PHTHALIMIDES; PYRIMIDINES; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 33644933323     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.09.009     Document Type: Article

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